P62623 is a cross-reference for ZP_05439211.1, which is represented by XP_002366385.1 in NRDB40.
| Set | Shortcuts | Acc.No. | Identifier | Database | Description |
|---|---|---|---|---|---|
| NRDB | IBP | ZP_05439211.1 | 256025346 | RefSeq | 4-hydroxy-3-methylbut-2-enyl diphosphate reductase [Escherichia sp. 4_1_40B] |
| NRDB40 | IBP | XP_002366385.1 | 237834175 | RefSeq | lytB domain-containing protein [Toxoplasma gondii ME49] |
PSI-BLAST Results for XP_002366385.1 against NRDB40
Filtering conditions for the hit sequences
- E-value is less than
Matches:
[1-50][51-94]
Match Overview
| Score | E-value | Shortcuts | Acc.No. | Description | ||
|---|---|---|---|---|---|---|---|
  | - | IBP | XP_002366385.1 | lytB domain-containing protein [Toxoplasma gondii ME49] | |||
  | 1066 | 1E-113 | IBP | C0ER49 | Lipoprotein signal peptidase - Neisseria flavescens NRL30031/H210 | ||
| 1059 | 1E-112 | IBP | C4DLI4 | 4-hydroxy-3-methylbut-2-enyl diphosphate reductase - Stackebrandtia nassauensis DSM 44728 | ||
| 1053 | 1E-112 | IBP | ZP_05048201.1 | 4-hydroxy-3-methylbut-2-enyl diphosphate reductase [Nitrosococcus oceani AFC27] | ||
| 1037 | 1E-110 | IBP | ZP_04940758.1 | LytB protein [Burkholderia cenocepacia PC184] | ||
| 1035 | 1E-110 | IBP | ZP_02537792.1 | 4-hydroxy-3-methylbut-2-enyl diphosphate reductase [Endoriftia persephone 'Hot96_1+Hot96_2'] | ||
| 1041 | 1E-110 | IBP | C4DRE0 | 4-hydroxy-3-methylbut-2-enyl diphosphate reductase - Stackebrandtia nassauensis DSM 44728 | ||
| 1005 | 1E-106 | IBP | ZP_01874889.1 | LytB protein [Lentisphaera araneosa HTCC2155] | ||
| 992 | 1E-105 | IBP | XP_002257762.1 | LytB protein [Plasmodium knowlesi strain H] | ||
| 995 | 1E-105 | IBP | YP_003160713.1 | hydroxymethylbutenyl pyrophosphate reductase [Jonesia denitrificans DSM 20603] | ||
| 992 | 1E-105 | IBP | ZP_03150701.1 | hydroxymethylbutenyl pyrophosphate reductase [Clostridium thermocellum DSM 4150] | ||
| 986 | 1E-104 | IBP | YP_002957672.1 | 4-hydroxy-3-methylbut-2-enyl diphosphate reductase [Micrococcus luteus NCTC 2665] | ||
| 981 | 1E-103 | IBP | XP_728969.1 | (E)-4-hydroxy-3-methylbut-2-enyl diphosphate reductase [Plasmodium yoelii yoelii str. 17XNL] | ||
| 968 | 1E-102 | IBP | XP_762798.1 | 4-hydroxy-3-methylbut-2-enyl diphosphate reductase LytB [Theileria parva strain Muguga] | ||
| 958 | 1E-101 | IBP | YP_153988.1 | 4-hydroxy-3-methylbut-2-enyl diphosphate reductase [Anaplasma marginale str. St. Maries] | ||
| 955 | 1E-100 | IBP | Q9BJX6 | LytB - Plasmodium falciparum | ||
| 957 | 1E-100 | IBP | XP_001611301.1 | LytB protein [Babesia bovis T2Bo] | ||
| 950 | 1E-100 | IBP | XP_002118841.1 | hypothetical protein TRIADDRAFT_62844 [Trichoplax adhaerens] | ||
| 934 | 4E-98 | IBP | YP_360744.1 | 4-hydroxy-3-methylbut-2-enyl diphosphate reductase [Carboxydothermus hydrogenoformans Z-2901] | ||
| 931 | 9E-98 | IBP | C0FBJ3 | Putative uncharacterized protein - Clostridium sp. M62/1 | ||
| 917 | 4E-96 | IBP | YP_001509968.1 | hydroxymethylbutenyl pyrophosphate reductase [Frankia sp. EAN1pec] | ||
| 912 | 1E-95 | IBP | ZP_03304220.1 | hypothetical protein ANHYDRO_00628 [Anaerococcus hydrogenalis DSM 7454] | ||
| 911 | 2E-95 | IBP | NP_697503.1 | 4-hydroxy-3-methylbut-2-enyl diphosphate reductase [Brucella suis 1330] | ||
| 911 | 2E-95 | IBP | C1SLB2 | 4-hydroxy-3-methylbut-2-enyl diphosphate reductase; SSU ribosomal protein S1P - Denitrovibrio acetiphilus DSM 12809 | ||
| 906 | 7E-95 | IBP | C2CFD8 | 4-hydroxy-3-methylbut-2-enyl diphosphate reductase - Anaerococcus tetradius ATCC 35098 | ||
| 899 | 5E-94 | IBP | YP_002432866.1 | hydroxymethylbutenyl pyrophosphate reductase [Desulfatibacillum alkenivorans AK-01] | ||
| 893 | 2E-93 | IBP | C0W9T3 | 4-hydroxy-3-methylbut-2-enyl diphosphate reductase - Acidaminococcus sp. D21 | ||
| 889 | 8E-93 | IBP | Q1Q304 | Putative uncharacterized protein - Candidatus Kuenenia stuttgartiensis | ||
| 886 | 1E-92 | IBP | YP_002573200.1 | hydroxymethylbutenyl pyrophosphate reductase [Anaerocellum thermophilum DSM 6725] | ||
| 887 | 1E-92 | IBP | YP_001692134.1 | fused penicillin tolerance LytB domain-containing protein/30S ribosomal protein S1 [Finegoldia magna ATCC 29328] | ||
| 877 | 2E-91 | IBP | ZP_01287160.1 | 4-hydroxy-3-methylbut-2-enyl diphosphate reductase [delta proteobacterium MLMS-1] | ||
| 875 | 3E-91 | IBP | YP_464729.1 | hydroxymethylbutenyl pyrophosphate reductase [Anaeromyxobacter dehalogenans 2CP-C] | ||
| 872 | 7E-91 | IBP | A3ERP9 | 4-hydroxy-3-methylbut-2-enyl diphosphate reductase - Leptospirillum rubarum | ||
| 868 | 2E-90 | IBP | C0QLG6 | IspH - Desulfobacterium autotrophicum (strain ATCC 43914 / DSM 3382 / HRM2) | ||
| 867 | 3E-90 | IBP | YP_001528270.1 | hydroxymethylbutenyl pyrophosphate reductase [Desulfococcus oleovorans Hxd3] | ||
| 867 | 3E-90 | IBP | YP_430185.1 | 4-hydroxy-3-methylbut-2-enyl diphosphate reductase/S1 RNA-binding domain protein [Moorella thermoacetica ATCC 39073] | ||
| 858 | 3E-89 | IBP | YP_461835.1 | 4-hydroxy-3-methylbut-2-enyl diphosphate reductase [Syntrophus aciditrophicus SB] | ||
| 856 | 5E-89 | IBP | YP_001917800.1 | hydroxymethylbutenyl pyrophosphate reductase [Natranaerobius thermophilus JW/NM-WN-LF] | ||
| 846 | 7E-88 | IBP | ZP_02081698.1 | hypothetical protein CLOLEP_03182 [Clostridium leptum DSM 753] | ||
| 846 | 8E-88 | IBP | C0GLE4 | Hydroxymethylbutenyl pyrophosphate reductase - Desulfonatronospira thiodismutans ASO3-1 | ||
| 841 | 3E-87 | IBP | YP_845932.1 | hydroxymethylbutenyl pyrophosphate reductase [Syntrophobacter fumaroxidans MPOB] | ||
| 832 | 3E-86 | IBP | A3AMD8 | Putative uncharacterized protein - Oryza sativa subsp. japonica | ||
| 829 | 6E-86 | IBP | NP_602581.1 | 4-hydroxy-3-methylbut-2-enyl diphosphate reductase [Fusobacterium nucleatum subsp. nucleatum ATCC 25586] | ||
| 828 | 8E-86 | IBP | XP_001758369.1 | predicted protein [Physcomitrella patens subsp. patens] | ||
| 824 | 2E-85 | IBP | C1TMG2 | 4-hydroxy-3-methylbut-2-enyl diphosphate reductase - Dethiosulfovibrio peptidovorans DSM 11002 | ||
| 825 | 2E-85 | IBP | YP_001741287.1 | putative bifunctional Cytidylate kinase / 4-hydroxy-3-methylbut-2-enyl diphosphate reductase (Cytidine monophosphate kinase / Isopentenyl-diphosphate:NAD(P)+ oxidoreductase) (cmk/ispH-like) [Candidatus Cloacamonas acidaminovorans] | ||
| 819 | 9E-85 | IBP | YP_001875303.1 | hydroxymethylbutenyl pyrophosphate reductase [Elusimicrobium minutum Pei191] | ||
| 819 | 1E-84 | IBP | A9P332 | Type 2 1-hydroxy-2-methyl-2-(E)-butenyl-4-phosphate reductase - Pinus taeda | ||
| 817 | 2E-84 | IBP | A9CBE5 | 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate reductase type 2 - Ginkgo biloba PE=2 SV=1 | ||
| 816 | 2E-84 | IBP | A9P331 | Type 1 1-hydroxy-2-methyl-2-(E)-butenyl-4-phosphate reductase - Pinus taeda |
Stacked Multiple Aligment
1 1 1 1 1 1 1 1 1 1 2 2 2 2 2 2 2 2 2 2 3 3 3 3 3 3 3 3 3 3 4 4 4 4 4 4 4 4 4 4 5 5 5 5 5 5 5 5 5 5 6 6 6 6 6 6 6 6 6 6 7 7
1 2 3 4 5 6 7 8 9 0 1 2 3 4 5 6 7 8 9 0 1 2 3 4 5 6 7 8 9 0 1 2 3 4 5 6 7 8 9 0 1 2 3 4 5 6 7 8 9 0 1 2 3 4 5 6 7 8 9 0 1 2 3 4 5 6 7 8 9 0 1
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The representative sequence for the query: MQMSVQLGGGEPDGGCAVSREIGSPHDVETSLVLSSSSPPSLRDECESFPDSQLSTTALVSLPHTHASSMRSSRCLEVNPTRGWTLPSVSPLSAPSSSPSSPCSIASSSLCSSALSSPASSAPSSSLSACFVSCRSSQSPSFSPSFCLSFPPAVSLSFGQLLSLLVLALILLFPEMRGGPLCSEAVLHHFARQAAPEVSRSARPILSPDLPSASPSSSHTSPLTAPPPRFFSSSFSSILAPSPRYSRHSSLSSSASAPFWVTSEAVRGIKVACARPAPLAFAFAPSVRVSSRPYSPFLGHASRSPFSFSSSPPSSSSSSRFGVSYSASSACSLSPRPLRNTSPSSSLRLSSSSHSSSPPSPSSPPSASSPASGKEESEGISLLLSKPRGFCAGVSRAVGIVEEALRIWGPPVYVKHSIVHNEVVCEAMRKKGAVFVEEISDIPRGAVAVFSAHGVSPAVRAEAEARQLQVVDATCPLVTKVHVYVKQKAEQGYHIILIGHKNHVEVIGTQGEAPGAVTVVESVEDVEQLSFSDSQKLFYATQTTLSLDDCGAIRQALIEKYPKIETIPSGSICYATTNRQTALQRLAPETDLTIVVGSEASSNAKRLVETAQRRGTTAYLVNDPNAIDPRWLENVKRISLTSSASTPEETTGAVVRRLEELGVAVVSEHEGILERVPKWKFPKNLLEAGKKKLDDTSRQTALGVETLVARDS
XP_002366385.1 lytB domain-containing pro MQMSVQLGGGEPDGGCAVSREIGSPHDVETSLVLSSSSPPSLRDECESFPDSQLSTTALVSLPHTHASSMRSSRCLEVNPTRGWTLPSVSPLSAPSSSPSSPCSIASSSLCSSALSSPASSAPSSSLSACFVSCRSSQSPSFSPSFCLSFPPAVSLSFGQLLSLLVLALILLFPEMRGGPLCSEAVLHHFARQAAPEVSRSARPILSPDLPSASPSSSHTSPLTAPPPRFFSSSFSSILAPSPRYSRHSSLSSSASAPFWVTSEAVRGIKVACARPAPLAFAFAPSVRVSSRPYSPFLGHASRSPFSFSSSPPSSSSSSRFGVSYSASSACSLSPRPLRNTSPSSSLRLSSSSHSSSPPSPSSPPSASSPASGKEESEGISLLLSKPRGFCAGVSRAVGIVEEALRIWGPPVYVKHSIVHNEVVCEAMRKKGAVFVEEISDIPRGAVAVFSAHGVSPAVRAEAEARQLQVVDATCPLVTKVHVYVKQKAEQGYHIILIGHKNHVEVIGTQGEAPGAVTVVESVEDVEQLSFSDSQKLFYATQTTLSLDDCGAIRQALIEKYPKIETIPSGSICYATTNRQTALQRLAPETDLTIVVGSEASSNAKRLVETAQRRGTTAYLVNDPNAIDPRWLENVKRISLTSSASTPEETTGAVVRRLEELGVAVVSEHEGILERVPKWKFPKNLLEAGKKKLDDTSRQTALGVETLVARDS
C0ER49 Lipoprotein signal peptida ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PSENGTHMTQKTIILANPRGFCAGVDRAISIVERALEEFGAPIYVRHEVVHNKFVVDNLRAKGAVFVDDLADVPKGATLIYSAHGVSKAVQEEAVQRGFRIFDATCPLVTKVHKEVARLDEQDYEIIMIGHKGHVEVEGTMGQLPGKMFLVETVEDVAGLNVKNPDKLAYVSQTTLSVDETKDIIAALNQRFPNIRNPHKEDICYATTNRQTAVKELAEECDLVIVVGSPNSSNSNRLREVAALRGVDAYMVDNASYLKKEWFENKTKVGVTAGASAPEVLVREVLQTIQDWGHETIREGEGAEESIV-FVLPKELRREGENK--------------------
C4DLI4 4-hydroxy-3-methylbut-2-en --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MTTEARTVVLASPRSFCAGVERAIEIVELALERFGAPIYVRKQIVHNTHVVARLEGEGAIFVDDLDAVPDGACVVFSAHGVAPSVRAEAESRGLDVIDATCPLVAKVHTEARRFAERGDTILLIGHSGHEEVEGTMGEAAG-IRLVESLADVDSLTVEDPSKVAYLTQTTLSVDETAEIIAALRRRFPKLRGPGGDDICYATSNRQEAIVEVAREADLVLVVGSRNSSNSRRLTEVAATAGTPAHLIEDAGQIRTEWLTGARVIGLSAGASAPPHLVEAVIAHLRGFGPVTVTERHTVEENVT-FSLPLVVRQPLGVLLAPFLERLRLGVDEL-----
ZP_05048201.1 4-hydroxy-3-methylbut-2-en ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------APSNNRIKLMKVTLAQPRGFCAGVVRAIDIVEHALEIYGAPIYVLHEIVHNQHVVEDLQRRGVIFTEDLASIPAGSVTIFSAHGVSTAVVETAKKNDLQVIDATCPLVTKVHLQAKKYYRQGDELIIIGHAGHPEVEGTRGRVKGTVYVLDSVAEVENLAVKDPEHIAYVTQTTLSIDDTRDVVDALKKRFPKIHGPGLDDICYATQNRQNAVREMSKKVDILLVVGARNSSNSNRLREVGEQNGITAHLIQDAKDLDSSWFTSQSRVGITAGASTPEILVQGVLNELRSYGVEEVMDLDGVQESI-SFRLPTMLPRAKLRQKQ------------------
ZP_04940758.1 LytB protein [Burkholderia ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ILLAQPRGFCAGVDRAIEIVERAIAMHGAPIYVRHEIVHNKYVVEDLKKKGAIFVEELEEVPAGNTVIFSAHGVSKAVRDEADVRGLRIYDATCPLVTKVHVEVAKMRQDGVDIVMIGHKGHPEVEGTMGQVERGMHLVESVEDVQKLELADPERIALVTQTTLSVDDAAEIIGALKAKYPKIREPKKQDICYATQNRQDAVKFMAPQCDVVIVVGSPNSSNSSRLREVAEKRGVAAYMVDAPDQIDPAWVAGKRRIGVTAGASAPEVLAQAVIARLRELGVRNVRALDGIEENV-SFPLPRGL---------------------------
ZP_02537792.1 4-hydroxy-3-methylbut-2-en ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------IILANPRGFCAGVDRAIEIVQRALDMLGAPIYVRHEVVHNRFVVESLRQRGAIFVDELSDIPDGNTVIFSAHGVSQTVRQEAQRRDLRIFDATCPLVTKVHLEVARRCRDGYEVILIGHRGHPEVVGTMGQCRSRIHLVVTPSDVEQLQISDSSRVAFVTQTTLSIDDTALVIAALQQRFPNIEGPKKNDICYATQNRQDAVKELAEQCDLVLVVGSPNSSNSNRLCEIARRHSTPAYLIDGAEDIDRSWLAGKARIGVSAGASAPEVLVERVLERLQEWGADQINEGAGKTEEVV-FSLPE-----------------------------
C4DRE0 4-hydroxy-3-methylbut-2-en -----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------RPRTVLLASPRSYCAGVERAIEVVERALERHGQPVYVRKQIVHNAHVVAELEKRGAVFVDELDQVPDGATVIFSAHGVSPAVRDDADSRGLAAIDATCPLVTKVHAEARRFADRGDTVVLIGHDGHEEVEGTMGEAPESMVLVESVADVERLRVPDPRRLAYLTQTTLAVEETEEIIAALRARFPALRGPGSDDICYATTNRQHAVAAIVDDCDLVLVVGSANSSNSRRLVELAERHGRMARLIDSAEDIELDWLTGADTVGLSAGASAPQILMDEVVETLAGFGPIDVVERVVTAED-QSFVLPREVR--------------------------
ZP_01874889.1 LytB protein [Lentisphaera -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------KIQGKIMKLIMAAPRGFCAGVERALKIVDEALELLPHPIYVNHEIVHNSHVVEFYKKKGVIFVEEIDDVPDGSSFIFNAHGVPPSLVKASKERGMKIVDATCPLVSKVHFEAIRYAKQGYKIILIGHEGHPEVIGVMGEAPDAIYLVEKPEDVDDLEFTQDDKIAYITQTTLSVDDCAAVISSLKKRYPGVSEPKKADICYATTNRQEAVKQIAEKCDVFLIVGSPNSSNSNRLREVAKAKGLDAYMVNCAEGLDPKWFEGKQTLGLSAGASTPEKIVSAVVDRLKECGLIEVSEFISREEN-EHFALPK-----------------------------
XP_002257762.1 LytB protein [Plasmodium k ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SGGTPKEGEKILYLVSPRGFCKGVSRAIDTVEECLQMFKPPIYVKHKIVHNDIVCKRLEEKGAVFIEDINEVPDGNILIYSAHGISPQIRELAKKKKLIEIDATCPLVNKVHMYVQMKAKEGYKIILIGYKNHVEVIGTFNEAPESTYVVQNVEQIDDLPFTEKDKLFYVTQTTLSMDDCSLIVKRLKEKFPQIETIPSGSICYATTNRQTALNQICQQCDLTIVVGSQSSSNAKKLAYSSELRNTPAVLVNSVDDFDFSSLRDVKTIALTSAASTPEELTQKFVEVLKEPFHYTLRLFEPVQENVPKWKLPKNLLGLIEERRRE-----------------
YP_003160713.1 hydroxymethylbutenyl pyrop -----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------TGKRVLLAAPRGYCAGVDRAVIAVEKALEVHGAPVYVRKEIVHNKFVVETLTDRGAIFVNETDEVPEGARVVFSAHGVSPAVVASAQQRNLQTIDATCPLVTKVHKEAVRFASDDYDILLIGHDGHEEVEGTAGEAPDHIQVVNSPDEVDKVVVRDPDKVVWISQTTLSVDETMETVRRLRERFPTLQDPPSDDICYATQNRQVAMKKLAPHCDLVLVVGSTNSSNSVRLTEVALDAGARAYLIDYAKEIDETWLDGVETVGLSSGASVPEILVQDVLKFLADRGYADVQEVRTATEDLL-FSLPRELRADLKKA--------------------
ZP_03150701.1 hydroxymethylbutenyl pyrop -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MEIIVAKSAGFCFGVSNAVKTVNNLLENQKEPIYTYGPIIHNAQVVDLFTSKGVKKIDDIDEAEPNGHIVIRAHGVTPDIYKKISDKGLILEDATCPYVKKIHNLVKEKSEEGYKIIIVGDRNHPEVIGINGWCNNQAYIVDSVDDVEKFPTSD-EKVCVVAQTTITNEKWLEVNTALKKKFKNI--LKFDTICSATSRRQNEAEEIAKNVDMMIIIGGKNSSNTQKLYDICKKHCNLTYKIETSGDLPPVDIKKIKKVGISAGASTPDWVIEEVIKKMSELGMVDILENDGAFENSFVRIHAGDTVKGKIIGFNSNEVFVDLGADGII----
YP_002957672.1 4-hydroxy-3-methylbut-2-en ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PVSGEKR-----VLLAAPRGYCAGVDRAVVAVEKALEHHGAPVYVRKEIVHNRHVVDTLTERGVVFVDELDEVPEGALTVFSAHGVSPAVVEEAAQRNLRTIDATCPLVTKVHREAVRFAKQDKRILLIGHDGHEEVEGTFGEAPEHTTVINDVAEARTVQVEDPDNLIWLSQTTLSVDETLEIVSVLRERFPHLQDPPSDDICYATSNRQAAIKSISPECDLVIIVGSANSSNSVRLKEVAAEYGARAERVDFANQVDESWFEGVATVGLSSGASVPEVLVQEVLALLAEYGYGQVDEVVTAEEDII-FSLPKELR-AELKRVGDESRSL------------
XP_728969.1 (E)-4-hydroxy-3-methylbut- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LYLVNPRGFCKGVSRAIETVEECLKTFKTNIYVKHKIVHNDIVCKDLENKGAIFIEDLNEVPDGSILIYSAHGISPQIKELAKKKKLIEIDATCPLVNKVHVYVKMKAKEGYKIILIGYKNHVEVIGTYNEAPDCTYIVENVEQVNNLNFTENQKLFCVTQTTLSVDDCALILNKLKEKYPNIETIPSGSICYATTNRQRALNKICTECDITIVVGSQSSSNAKKLVYSSQIRNTDAILINTINDLDFSILKNVKKIALTSAASTPDELTQQFVKVLTNPPYNKLNIFNGVEEIVPKWKLPKELINMIKQKKEEQT---------------
XP_762798.1 4-hydroxy-3-methylbut-2-en --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------EPQTPKKVYLVKPRGFCEGVSRAIRTVEEALRVFGPPIYVKHEIVHNEAVCNRLRARGVVFIEDLNLVPENSVLIYSAHGVSPEVKELAKTRNLVEIDASCPLVNKVHVYVKNKAKEGYKIVLIGHKNHQEIIGTSGEAPEAVTVVENVADVEKLDYPEGTKLYYVTQTTLSLDDCKEIKEALVKKYPQIETIPSGSICYATTNRQTAIHKVTEFVDLVLIVGSTMSSNAKRLVEAALNRNIRSYLVFDSNDVTEELVGSARNIALSSSASTPEDLTFAVLEKLKSPPFNFLEEFDGAIERVPNWRLPRNL---------------------------
YP_153988.1 4-hydroxy-3-methylbut-2-en -----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GNVEVILARPRGFCAGVERAVRTLESVASRYAREVYALHEIVHNLHVVNSFKKMGVKFVSALHEVPEGAVLVFSAHGVSQQVKEESRRKGLTVVDATCPLVTKVHLEIQRYDKSGYQVILVGHKGHREVEGSMGQVSNPVVLVQNVQDVQSIKIPSAAKLAYVTQTTLSMDDTAEIISALKLRFPRIVGPDLRDICYATQNRQTAVKAMSQMVDVVLAIGSKNSSNSNRLLDLAKAQNARAYLIDSYRNIDLEWLIGARRIGITAGASAPEILVQEVIDYLGLHANLKVRTMDGVSENIT-FKLPE-----------------------------
Q9BJX6 LytB - Plasmodium falcipar ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LYLINPRGFCKGVSRAIETVEECLKLFKPPIYVKHKIVHNDIVCKKLEKEGAIFIEDLNDVPDGHILIYSAHGISPQIREIAKKKKLIEIDATCPLVNKVHVYVQMKAKENYDIILIGYKNHVEVIGTYNEAPHCTHIVENVNDVDKLNFPLNKKLFYVTQTTLSMDDCALIVQKLKNKFPHIETIPSGSICYATTNRQTALNKICTKCDLTIVVGSSSSSNAKKLVYSSQIRNVPAVLLNTVHDLDQQILKNVNKIALTSAASTPEQETQKFVNLLTNPPFNTLQNFDGAHENVPKWKLPKNFLHMIKEREK------------------
XP_001611301.1 LytB protein [Babesia bovi ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------VFLLEPRGFCAGVRRAIETVEEAVRIFGPPIYVKHEIVHNEFVCNTLKKKGVIFIEDIETVPEGSILVLSAHGVPPSVHEMVKKRNLVEIDASCPLVNKVHVYVRKKAEEGYKIILIGHKSHVETIGTLGEAPDVTTVVETVDDVDRLEYSRDTPLFYATQTTLSVDDCKIIKDRLLERFPWIETIPSGSICYATTNRQFAVRDACNFCDLVLVVGSSLSSNANRLVDTANLRNVRAHLIPNADAITEELIGDARKIALSASASTPDELTADVVKKLAVPPYNNIEIYHSCDERVPKWRLPRNLELYIKE---------------------
XP_002118841.1 hypothetical protein TRIAD ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------AISKIKLDKLEIFMANPRGFCAGVERAVEIVELTLAKYGAPVYVRHEIVHNRYVVENLKNKGAIFVEEIAEIPDNAVTIYSAHGVSEKVENESRFKHLKIIDATCPLVKKVHLQAQKFEKVGDKIIIIGHKNHPEIEGTSGRVKREVFIVENIQDVEKIPFSKDESISYVTQTTLSVDDTKNIIDALKNAFPNIKGPELKNICFATQNRQDAVKQLASLVDTIFVIGAKNSSNSNRLRDIAENCGTKAFLLNGETDDISDLLHNSTKLGITAGASAPEILVSNLIAKIKKMRDVKITHVEGTAFSEQERDL-FDLRGFLPPGIEDQEVQVS-----------
YP_360744.1 4-hydroxy-3-methylbut-2-en -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MEIIVAQNAGFCFGVKRAIETAQKAAENNN-PVYSLGPLIHNPQEVERLKKAG-IIPIEEIEEGNGKTIIIRSHGTTPEKLQEIVDRGYVVEDATCPFVKKAQILAQKLTDEGYQVVVVGDKKHPEVQGIVGWSGYKALVVENPEEAARLPFYP--KIAVIAQTTQKSENFWQVVEVIKKKGG--EVRPFNTICHATRTRQEESRKLATEVEVMLVVGGKNSANTKKLAQICAATNTPTYLIEEASEIKPEWFAGKAKVGITAGASTPAWIIEEVRKKVEQMASMELLEIKPVKE--------GEIVRGKVVKVLEKEVLVDIGTKG------
C0FBJ3 Putative uncharacterized p ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------AAGESQTSPIEVRVAKTAGFCFGVKRAVEQVYEQIEKGNGPIYTYGPIIHNEEVVRDLEEKGVRVIDTKEELSSKGVVIIRSHGVGREIYEILEHNGITVVDATCPFVKKIHRIVKEQGEEGRRVIIVGDESHPEVQGIKGWGNDDTLVIKTAEELERLPLRDGERLCVVAQTTFNYNKFKDIVEKIKTRYD---ILVLNTICNATQERQVEAKQIASEVDAMIVIGGKNSSNTQKLFEICRRECKNTYYIQTLSDLKPEKAGSVRSVGITAGASTPNNIIEEV----------------------------------------------------------
YP_001509968.1 hydroxymethylbutenyl pyrop ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LLLAEPRAFCAGVERAIEVVERALEIHGAPVYVRKQIVHNTHVVADLASRGAVFVEELDEVPPGATVVFSAHGVAPAIWDEAGERDLAVIDATCPLVEKVHAEARRFTARGDTVLLIGHSGHEEVDGTLGEAPGRIQLVESAAAVEDIEVADPERVTYLMQTTLAVDEAEEVVDALRDRFPAVVGPGSADICYATSNRQNAVRRVAAEAELVLVVGSENSSNSRRLVEVSERDGVAAHLVESVEDVQLDWLKGVRTVGISAGASAPPLLVEELTAALSGLGSASVSVRSVGSESI-SFHLPKEVRRPLSERR-------------------
ZP_03304220.1 hypothetical protein ANHYD -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MKVIVAKNSGFCNGVRRSVDLANKASE-KNKKTYTLGPLVHNPTQVQMLEDKGVGVIDENEVIKNDSQIVIRSHGVREELKDNIRKNQNNVIDATCPVLINIYKKIKEKENEGYKVVIVGDKNHPEIKAMASYINDGIII---KDETEAKNITNMSKLYVVSQTTNRIDFFENIAHELEK--TNDDVVIENTICNATRLRQEACKSLSKEVDCMVVVGGFNSSNTNKLYQIAQKYCKNVQRIETVKDLPLQKLSNFNIIGVIAGASTPDKVIEEVVNRMDDL---TNEELMNSIEDSMKKIYPRDVVNGTIIDVKDDEVFVDIQADGIVKLD-
NP_697503.1 4-hydroxy-3-methylbut-2-en ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------AIMTQQRPPLEIRLCGPRGFCAGVDRAIQIVVLALKKYGAPVYVRHEIVHNRYVVEGLQARGAIFVEELDEIPRNQPVVFSAHGVPKSVPADAEAKNLFYLDATCPLVSKVHKQAMRHQRLGRHVILIGHSGHPEVIGTMGQLPDGAVLIETVEDAHTCHFDDEDNLGFVTQTTLSVDDTAGIIKELQARFPNLAAPAAESICYATTNRQDAVRAAAPGCDLFLIVGAPNSSNSKRLVEVAEKAGARSMLVQRAEDIEWEQIGDISVVGLSAGASAPEIIVDEIIDAFKAHFDVKIELAETTVET-ENFLVNREIRDVELTVKD------------------
C1SLB2 4-hydroxy-3-methylbut-2-en -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------VEIFIADHAGFCFGVERAVSLVEDTSKQFTG-VYTLGPIIHNPQIVSKFAENGIGVCYNPEEVNEDNTVVVRSHGVTKETYATLASRKVNVVDATCPFVKKAQNSAKKLGNEGAVVVVYGEKNHPEVKSIVSFIDSRYVIVSDVGEASVLP--DENCYALVAQTTQNSESFDKIAEILKTKCDKL--IIKNTICNATSLRQASAIDLAKKVDIMVVIGGRNSGNTTRLYEICKNICANTHHIETKEELKKEIFDGCRKVGITAGASTPGYLVEEVIEFLKEVSMSSINNNDGMLEESFQQPEKNSIVQGTVAQINENDVLVNIGFKT------
C2CFD8 4-hydroxy-3-methylbut-2-en -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MEIIIAEFSGFCGGVRRSVDLANEALKIKGDK-FSIGPLIHNPQLVSEFEASGLKVLDKDEASNNDSTVLIRAHGESADFKKLLAENGNKILDATCPVLMNIYKKIMAKEAEGYQVVIVGDKKHPEIIAMESFLNNGIIV---SDETEAKNIKVDNKLYVVSQTTNRLDYFYDIANKLKEN--NDSVVIENTICKATENRQKAAKSLAEEVDCMIVVGGFNSSNTNKLYQVASLYCKNVFRIETVKDLPLQKLSKFKKVGIIAGASTPDKIIEEVVSSMDEF---TKEEFMNSLEDSLKKIYPKEIVKGTVIDVKDDEVFVDIQADGIIKLD-
YP_002432866.1 hydroxymethylbutenyl pyrop -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MKITIAKTSGFCMGVRRAVEMVLDTANRVKGPVYTFGPLIHNPQVMHMLAEKGVEVLEEIPEKGEG-TVLIRAHGVTPETRGRLEAAGFTVIDATCPRVIKVQRLLDKYQAEGYTPIIVGDADHPEVIGLVGHARGHAYVVRSREEA--LNLPKGEKAVLVAQTTQDQVLYLNILEAVRERFDEIK--DFNTICDSTARRQEEARGLAHQVEAMVVVGGKSSGNTQRLAQIAAGSGVPTFHVETEKELDVTKFQGMEHVGITAGASTPNWIIRRVHQAVADPGV-------------------------------------------------
C0W9T3 4-hydroxy-3-methylbut-2-en -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MQIIVADPCGFCYGVKRAIDIAQMNVKGYNTSIATLGEIVHNPRVVESLAQKGVQCKETLADFSAGDTVIFRSHGAAPQIYEEAEQKGLKIIDATCPHVRKAQKTAAALSKEGRFVIIIGEKRHPEVQSIKAWAGKDSLVIETADDLESLPVRD--KFGVVSQTTFEAGKFNLLLHLSQEK-RSGDYKVERTICTATAERQEAARKLAGNCDAFFVFGGKNSANTRHLAELARPINPRTYLLQDASEITLSMLAGAEKIGITAGASTPQEIIEEAIVAME-----TMEELLGQEESMKLHI--GMIVEGTVIDVTKDEVVVNFGYQS------
Q1Q304 Putative uncharacterized p -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LKVFVAKTAGFCMGVRRAMDILLDAANEKGAKVYTDGPLIHNPQVLEYLEKRDLHIVNDVTDLS-NSTVVIRAHGVTPSRRAEIESKGAKVCDATCPHVMRVQSIIKKYAAQGYSTIIVGDNGHAEVVGLLGYAEGRGHVVENMENIELLPPMD--KVCIVAQTTQDRHLFKRAIDEIKRRYPNSE--SFETICSSTYKRQDEVVNLCKSVDAMIVVGGRGSANTTRLVTICESQGTPTFHVETDSEIDLNKLKVFNTIGVTAGASTPNWMIKRVVDKVRTYKVNK-----------------------------------------------
YP_002573200.1 hydroxymethylbutenyl pyrop -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MIIKVAQSAGFCFGVQRAVEVLAWAKANKGKSIKVYGMLIHNSYVIDKLKDLGVKVVEDIEQIGKEDIIFIRSHGVSMEEYAEIEKRADKVYDFTCPYVKKIHEIVMEHSVNGYDIIVVGDMNHPEVKGIVGHVGNKCFVVDSIEKVKEAINQIEGKAAVVCQTTFDGKKWSEIREFL-ESHTNYKV--FDTICKATINRQKEAQELAQHVDIMLVVGDKKSSNTNKLYKLLKEI-KPTFFIEKVEDLDSIKLDSYKSIGVTAGASTSPEQIEEVVKHLEEFNEMNLKDFERLIDRSFLTVQRGEVVNGRIIKVEEDYLLVDIGAEGIIYKD-
YP_001692134.1 fused penicillin tolerance -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MNIIVQQNAGFCYGVKRAINIIENDPSEIK---YTLGQLIHNEQECKRLENLGIKQIDDYTQAEKGSTIFIRSHGATLKLKQEIINNGYKLVDLTCPSLLKIYEKINKKHDEGYKIIIIGDPNHPEIIAMKGQVENNIEVVNSIDEAKKI---KGEKLYVISQTTNLKRKFLEISDIIVE--GNTNVVIDNTICGATKSRQMACLELSKNVDCMIVIGGLNSSNTNKLYEIAKQNCKKVLRIETYKDICDDSIIESKLLGITAGASTPAWIIEEVVNLMDNYSKDFMEQV----EESMNKIYPKEIVKGEVIYVTDDEVMVNIGADGIIKLD-
ZP_01287160.1 4-hydroxy-3-methylbut-2-en -----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------EPMKVILAKHAGFCMGVRRAVETTLELVEKSRGPIATFGPLIHNPQVLTMLGQKGVEVLEEVPEQSQG-TVVIRAHGVPPARKQSLEESGAVVEDATCPRVVKVQAIIDKYRRQGYTTVIVGDRDHAEVEGLVGHAGEVGLVISSMEELDGLELKPP--YIVVSQTTQDEEMFQLITAGVLSRFPGGKV--FNTICDSTHKRQDEVREMCRQVDALVVVGGRNSANTKRLAEIARGLACPVFLVETEAELQFEQMRRYQSVGVTAGASTPVWSIRQVVDALEAL---------------------------------------------------
YP_464729.1 hydroxymethylbutenyl pyrop ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PARGAPLYRGVDVKIAKTAGFCWGVRRTVDKVMEVADQHRAPVVTLGPIIHNPQAVARFSEKGVGTVNGIGEVADGTTVVVRTHGAVREELERAEARGLEVVDGTCPYVKYPQAMAQRLSREGYHIVIVGDANHAEIKGVISYSEQPCTVVKPGGPVPEI---KAKKVAVIAQTTCIGAEFERVVGVLALRHKEVRAV--NTICNDTEERQADARALASEVDAVVVVGGKNSANTRHLAEICRAIQPRTWHVETEAELEAAWFDGCRVVGLSAGASTPDWVVEGVAAWLRALR--------------------------------------------------
A3ERP9 4-hydroxy-3-methylbut-2-en -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MDIFLPEYAGVCVGVKRAIKMAHKTAEEATGPVFILHEIVHNTHVVKDLSERGVKSVDEVKEVDKG-TLIISAHGVAPEVIADARSRNLEVVDTTCPLVWKIHRIVKALAEKNYTIFLLGERNHDEVMGVQGVAKDHIHIFHKKEEIAHLPLTEG-PVALVSQTTQSIKYFDEILDLLLERYPQLEI--HNTICDATEKRQTSALAIAGDMDVMITVGSMSSANSRRLQEVSAGLCRASYLVDSANEVSDTWFKGGERVGVTAGASTPEWLIEGVIEKLMEISRAKVTRNESSEEEFIETH--------------------------------
C0QLG6 IspH - Desulfobacterium au -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MKITIARTAGFCMGVRRAVDLVLDASNATKERICTYGPLIHNPQVLEMLEKKGIPSINTIPEKGEG-TVLIRAHGVPPQDKRQLELAGFKVIDATCPRVIRVQTIIKKHTDQGYASIILGDRDHPEVKGLLGYAGKGGVAVSSLAALEKLP--SFDRAIIVAQTTQDTHLFEQVKVWAQENHPEYKV--FDTICDSTEKRQAETRKMAQICDAVVVVGGRESGNTRRLAQVARDTGKPAFHIEDVSELDIKELAGAKHIAITAGASTPNWIINKTCRTLEN----------------------------------------------------
YP_001528270.1 hydroxymethylbutenyl pyrop -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MKVSIAKTSGFCMGVRRAVDMVLDASNRYTEPIYTFGPLIHNPQVLRLLAEKKISVMETIPEQGNG-IVLIRAHGVPPRTREKLEAAGFTVIDATCPRVVKVQTIISRNAAEGCAVIIIGDKDHPEVVGLLGYAGDRGVVADSLEALKALPA--FEKAIIVAQTTQSTRLFDEVGAWAAAHHPHYQV--FNTICPSTKNRQAETEALARQTDAMVVVGGYNSGNTQRLAQVSKKSGHPVFHVETSEELDTNALAKSDHIGITAGASTPNWIIKKIYRELE-----------------------------------------------------
YP_430185.1 4-hydroxy-3-methylbut-2-en -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MEVIVADYAGFCFGVKRAVEKAREA----PKPVASLGMLIHNRQVVDQLAREGVRPVASLDEVNCGRILI-RSHGTTPETLVRARDKGLEIIDATCPYVKRAQHLAQKMAAEGYQVIIVGDAAHPEVQGMLGWAGPGAVVVPDKKAAAALPFHPRR--AVLAQTTQPESRLEEVAAALRSNTDTL--VVHNTVCQATHQRQEAAVRLARQVDVMVVVGGKESANTRHLAELCRATGTPTYHVERAGELCRQWFINTRRVGVTGGASTPAWIIEEVVGMLTGEEKIMVPEEE------------------------------------------
YP_461835.1 4-hydroxy-3-methylbut-2-en -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSVFLAKTAGFCMGVKRAVDTVLDIARHKGEKIYTYGPLIHNPQTVEFLRERGIIPIKDIEALDQNAAIVIRAHGISPSERKKIRNKGLRIIDATCPKVTHVQAIIRQHAAKDYNILIIGDGDHPEVNGLLGHAGGHGRVIGSLQNVEELPI--MEKVCVVAQTTQNVEEYAAIVRRIRDRFP--ETVVFNTICDSTEQRQAEVRELAARMEAMVIVGGRNSANTRRLAALSSQQGTPTFHIETADELNDAKLAPYDRIGLSAGASTPNWIIDRVVDRIAE----------------------------------------------------
YP_001917800.1 hydroxymethylbutenyl pyrop -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MEILVAKGAGFCSGVNRALDKTIQAVQTDTSRVFTLGPIVHNKEVIQNLTEKGIGIIENLTQLETNNYVVIRSHGVGPETFKMLNNSNTDVIDATCPFVRKVQQKASKLYQDGYQIFIVGDPNHPEVKGIKEWTDNNAIVIEKPEQVNDIEISN--KTAVVAQTTLREEKFNEIVEKILDRNPN--TIVHNTICDATQKRQTATKELAGQVDVMIVVGGYNSSNTKKLKELAVKEGVPTYHIETAKELKTDWFLGCKKIGVTAGASTPDWTI-------------------------------------------------------------
ZP_02081698.1 hypothetical protein CLOLE ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ITVAKTAGFCFGVNRAIEIVNRLLDQ-GKRVYTLGPIIHNPQIVAALEQRGVTIVSQPGQVQPGGILVIRSHGVSLDILREIERLGIEYADATCPFVGKIHQIVFSASEKGVPVLIAGDPDHPEVRGIRGHCQGESYVFRNQNELKNLPNLESKELFVVAQTTFSVSEWENCLKILKRVYTNAAI--FDTICNATSERQAEAVRLAKQKDLMVIIGGRQSSNTAKLKSVCEPFC-RTCLIETAKELPVSEIKQAYSIGITAGASTPASIIKEALDILENKEMTEINEGEMNFEEMLEESLTDEKVHGVVVGIAPNEIYVDVG---------
C0GLE4 Hydroxymethylbutenyl pyrop ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------VLLAESAGFCMGVSLALGKLDKALENQTQRIFTYGPIIHNPQVLEYYHGKGVKIIDNWDEPRPGDMVLIRAHGVPLQVEEKLREKNIDILDATCPKVKKAQLLIYKNSAVSDRLLIYGELDHPEVKGLLSYAQCEAFLFENMQEFKKIALAPKDRYCLVSQTTQDRQEFLSIASELKHSQGN-EIITLDTICDATKDRQNETIKIAGQVECMFVVGGRNSGNTRRLYQVARKYCPRCLHIETKEEIDPEMVKGCSKVGLTAGASTPNSTIQSIYQYLHRI---------------------------------------------------
YP_845932.1 hydroxymethylbutenyl pyrop -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MKVLVAKTAGFCKGVRDALEVTLGAIKNQGENICTFGPLIHNRQVLAMLEAKGIREVNEIEGCAD-RKVVIRAHGIPPETRQTLHRLGATLLDATCKRVAKVHAAIKRHARRGYYTVIVGDADHAEVIGLMGYTEGRGVVINRVEQLNELP-AEWENVLLVAQTTQNEEVFQEIQEEFLKKYPKGKV--KNTICDSTHERQTEVREMCSLVEAMVIVGGFHSGNTLRLAQVARECEIPTYHVETEAELNPQELAKYSRVGVSAGASTPNWLIRNVVRFLESIRPEQ-----------------------------------------------
A3AMD8 Putative uncharacterized p ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------NQHTWGPVTVKLAEAYGFCWGVERAVQIAYEARKQFDDRIWLTNEIIHNPTVNKRLEDMGVQNIKDFDVVEQGDVVVLPAFGAAVEEMYTLNEKKVQIVDTTCPWVSKVWNMVEKHKKGDYTSIIHGKYSHEETVATASFA-GTYIIVKNIAEASYVPDVDLVKVGIANQTTMLKGETEEIEKTMMRRFGNDHFIAFNTICDATQERQDAMYQLVKEVDLILVVGGWNSSNTSHLQEIGELSGIPSYWIDSEQRIGPNWLEGPITIGVTSGASTPDKVVEDALQKVFEIKRQEVLQ--------------------------------------------
NP_602581.1 4-hydroxy-3-methylbut-2-en -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MEIIRAKHMGFCFGVLEAINVCNSLVEEKGRK-YILGMLVHNKQVVEDMERKGFKLVNDMDELKEDDIVVIRAHGTSKSVHEKLKERKVKVFDATCIFVNKIRQEIEIANENGYSILFMGDKNHPEVKGVISFADD-IQIFESFEEAKKLKIDLDKTYLLSTQTTLNKKKFEEIKKYFKENYKN--VVIFDKICGATAVRQKAVEDLAVKVEVMIIVGDTKSSNTKKLYEISKKLNDNSYLVENEEQLDLSIFRGKEVVGITAGASTPEETIMNIEKKVRGYKMSNVNENQNEFSLMLEEFLPNQEKRGVIESMDQNFSYLDVPGERTAVR--
XP_001758369.1 predicted protein [Physcom -----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GNVTVKLANSYGFCWGVERAVQIAYEARKQFEQKLWLTNEIIHNPTVNQKMTDMGISELKDFSVVDQGDVVILPAFGASVQEMQILDDKKVQIVDTTCPWVSKVWNTVEKHKKGTYTSVIHGKYAHEETVATASFA-GKYIIAKNIKEATYIPDTDLEKVGIANQTTMLKGETEEIEKTMMQKYGTNHFMSFNTICDATQERQDAMFKLVEKVDLILVVGGWNSSNTSHLQEIAELKGVPSYWIDTEERMKDDWLEGPITVGITSGASTPDKVVEDVLQRLFQFKREEVLQ--------------------------------------------
C1TMG2 4-hydroxy-3-methylbut-2-en -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MKVVVAEPTGLCFGVKRAIRTMEEALEEKG-RVFCIGSPIHNPQEVQRLVDKGLVVVEDDDRIPPDEPVFVRAHGISPDVHQRLQDKGARIIDGTCPFVRKAQEMAGRLSREGYYLVVLGDENHPEIKGILGYVEGPYLVVSGKKDLRAIDKIDKIGII--SQTTQQESTLKELVSEAVGSAREIKV--SNTICRATVERQEAVRRLAYKVDGIVIIGGHNSANTGKLFRIAQESGTPALWVEQADQLDGRWLSGKGTIGIAAGASTPDWLIKQLQQAM------------------------------------------------------
YP_001741287.1 putative bifunctional Cyti -----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------RKIKIRLANYLGYCFGVKRAIQMAKDA-KVTEKPVYTLGELIHNPAIVQELEEQGIHIVNKAEEV-KNSTVIIRSHGITKEEYKILKENNNEIIDATCPYVKRTHTILKHLVKENYPVLILGDKQHQEVIGIRSYGNEKTFVI---GEDDPIPKIKEKRLAIMAQTTQRIEKLQELVYKLLSNFNELRV--FNTICLATTQRQKAAEELAQESDAMFVIGGLKSSNTCALAKLSSVYC-PTYHIEDEKQLASIDISPYKCIGITAGASTPEEMIIKVYNVLLQKSGDFKTV--TSIEEIPMFK--------------------------------
YP_001875303.1 hydroxymethylbutenyl pyrop ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------VTIAKSAGFCPGVKKAIDKVLELESSGKKPIFTLGPLIHNNQVIATLEEKGITSIGHPSEVEKEGVLVIRAHGITPEFQREVESCGKEVIDATCPLVKHVHNNISKYAGEGYTTVIVGDAGHAEVIGLLGYTQGRGYVV--ADESEVLALPDFDKVNIVAQTTQKEAAFYKLAELIKQK--AKEAVVSNTICEPTKQRQSETIEYAKNADFVIVVGGKNSANTARLAKLCGELAPKVLHVETEADLEGHDLKTPKKIFITAGASTPNWLIDRISGAVKNARMGAM----------------------------------------------
A9P332 Type 2 1-hydroxy-2-methyl- ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------NEFTWGNVTVKLAKSYGFCWGVERAVQIAYEARKQFPERIWITNEIIHNPTVNERLEEMDVHSIKRFDVVNKGDVVILPAFGASVHEMQLLSEKNVQIVDTTCPWVSKVWNTVEKHKQGEYTSIIHGKYSHEETIATASFA-GTYIIVKNITEARYVPDVDLVKLGIANQTTMLKGETEEIEKTMMRRFGNKHFISFNTICDATQERQDAMDDLVKEKDFILVVGGWNSSNTSHLQEIAELNDIPSYWIDNEQRIGPHWLEGPITIGITSGASTPDKVVEDALKKIFEIKREEVLQ--------------------------------------------
A9CBE5 1-hydroxy-2-methyl-2-(E)-b ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------NEYTWGNVTVKLAEAYGFCWGVERAVQIAYEARKQFEERIWMTNEIIHNPAVNKRLEEMKVQYIEQFDAVEIGDVVILPAFGAAVHEMQILSEKNVQIVDTTCPWVSKVWNTVEKHKKGDYTSIIHGKYAHEETVATASFA-GTYIIVKNIAEATYVPDVDLVKLGIANQTTMLKGETEDIEKTMMRRFGNEHFISFNTICDATQERQDAMDKLVKEKDLILVVGGWNSSNTSHLQEIAELNGISSYWVDGVQRIGPNWLEGPITIGVTSGASTPDKAVEDVLRKVFEIKQEEVLQ--------------------------------------------
A9P331 Type 1 1-hydroxy-2-methyl- ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------NEYTWGNVTVKLAESFGFCWGVERAVQIAYEARKQFDQKLWITNEIIHNPTVNQRLKEMQIEDIKKFDVVNNDDVVILPAFGAALSEMQILDEKGVKIVDTTCPWVSKVWNTVEKHKKESFTSVIHGKKGHEETVATSSFA-GKYIIVKDIKEATYVPDCDLVKVGIANQTTMLKGETEEIEKTMMQKYGNEHFMSFNTICDATQERQDAMYNLVKEKDLILVVGGWNSSNTSHLQEIAEQNGIPTYWIDSEKRIGPNWLTGPLKIGITSGASTPDKILEDTLKVVFKMKDEEALQM-------------------------------------------
Pairwise Alignments
XP_002366385.1 lytB domain-containing protein [Toxoplasma gondii ME49] Length: 712. Score: 2525. Identity: 100%. E-value: 1E-200. Query: 1 MQMSVQLGGGEPDGGCAVSREIGSPHDVETSLVLSSSSPPSLRDECESFPDSQLSTTALVSLPHTHASSMRSSRCLEVNPTRGWTLPSVSPLSAPSSSPSSPCSIASSSLCSSALSSPASSAPSSSLSACFVSCRSSQSPSFSPSFCLSFPPAVSLSFGQLLSLLVLALILLFPEMRGGPLCSEAVLHHFARQAAPEVSRSARPILSPDLPSASPSSSHTSPLTAPPPRFFSSSFSSILAPSPRYSRHSSLSSSASAPFWVTSEAVRGIKVACARPAPLAFAFAPSVRVSSRPYSPFLGHASRSPFSFSSSPPSSSSSSRFGVSYSASSACSLSPRPLRNTSPSSSLRLSSSSHSSSPPSPSSPPSASSPASGKEESEGISLLLSKPRGFCAGVSRAVGIVEEALRIWGPPVYVKHSIVHNEVVCEAMRKKGAVFVEEISDIPRGAVAVFSAHGVSPAVRAEAEARQLQVVDATCPLVTKVHVYVKQKAEQGYHIILIGHKNHVEVIGTQGEAPGAVTVVESVEDVEQLSFSDSQKLFYATQTTLSLDDCGAIRQALIEKYPKIETIPSGSICYATTNRQTALQRLAPETDLTIVVGSEASSNAKRLVETAQRRGTTAYLVNDPNAIDPRWLENVKRISLTSSASTPEETTGAVVRRLEELGVAVVSEHEGILERVPKWKFPKNLLEAGKKKLDDTSRQTALGVETLVARDS Sbjct: 1 MQMSVQLGGGEPDGGCAVSREIGSPHDVETSLVLSSSSPPSLRDECESFPDSQLSTTALVSLPHTHASSMRSSRCLEVNPTRGWTLPSVSPLSAPSSSPSSPCSIASSSLCSSALSSPASSAPSSSLSACFVSCRSSQSPSFSPSFCLSFPPAVSLSFGQLLSLLVLALILLFPEMRGGPLCSEAVLHHFARQAAPEVSRSARPILSPDLPSASPSSSHTSPLTAPPPRFFSSSFSSILAPSPRYSRHSSLSSSASAPFWVTSEAVRGIKVACARPAPLAFAFAPSVRVSSRPYSPFLGHASRSPFSFSSSPPSSSSSSRFGVSYSASSACSLSPRPLRNTSPSSSLRLSSSSHSSSPPSPSSPPSASSPASGKEESEGISLLLSKPRGFCAGVSRAVGIVEEALRIWGPPVYVKHSIVHNEVVCEAMRKKGAVFVEEISDIPRGAVAVFSAHGVSPAVRAEAEARQLQVVDATCPLVTKVHVYVKQKAEQGYHIILIGHKNHVEVIGTQGEAPGAVTVVESVEDVEQLSFSDSQKLFYATQTTLSLDDCGAIRQALIEKYPKIETIPSGSICYATTNRQTALQRLAPETDLTIVVGSEASSNAKRLVETAQRRGTTAYLVNDPNAIDPRWLENVKRISLTSSASTPEETTGAVVRRLEELGVAVVSEHEGILERVPKWKFPKNLLEAGKKKLDDTSRQTALGVETLVARDS C0ER49 Lipoprotein signal peptidase - Neisseria flavescens NRL30031/H210 Length: 495. Score: 1066. Identity: 46%. E-value: 1E-113. Query: 370 PASGKEESEGISLLLSKPRGFCAGVSRAVGIVEEALRIWGPPVYVKHSIVHNEVVCEAMRKKGAVFVEEISDIPRGAVAVFSAHGVSPAVRAEAEARQLQVVDATCPLVTKVHVYVKQKAEQGYHIILIGHKNHVEVIGTQGEAP-GAVTVVESVEDVEQLSFSDSQKLFYATQTTLSLDDCGAIRQALIEKYPKIETIPSGSICYATTNRQTALQRLAPETDLTIVVGSEASSNAKRLVETAQRRGTTAYLVNDPNAIDPRWLENVKRISLTSSASTPEETTGAVVRRLEELGVAVVSEHEGILERVPKWKFPKNLLEAGKKK Sbjct: 167 PSENGTHMTQKTIILANPRGFCAGVDRAISIVERALEEFGAPIYVRHEVVHNKFVVDNLRAKGAVFVDDLADVPKGATLIYSAHGVSKAVQEEAVQRGFRIFDATCPLVTKVHKEVARLDEQDYEIIMIGHKGHVEVEGTMGQLPPGKMFLVETVEDVAGLNVKNPDKLAYVSQTTLSVDETKDIIAALNQRFPNIRNPHKEDICYATTNRQTAVKELAEECDLVIVVGSPNSSNSNRLREVAALRGVDAYMVDNASYLKKEWFENKTKVGVTAGASAPEVLVREVLQTIQDWGHETIREGEGAEESIV-FVLPKELRREGENK C4DLI4 4-hydroxy-3-methylbut-2-enyl diphosphate reductase - Stackebrandtia nassauensis DSM 44728 Length: 478. Score: 1059. Identity: 44%. E-value: 1E-112. Query: 375 EESEGISLLLSKPRGFCAGVSRAVGIVEEALRIWGPPVYVKHSIVHNEVVCEAMRKKGAVFVEEISDIPRGAVAVFSAHGVSPAVRAEAEARQLQVVDATCPLVTKVHVYVKQKAEQGYHIILIGHKNHVEVIGTQGEAPGAVTVVESVEDVEQLSFSDSQKLFYATQTTLSLDDCGAIRQALIEKYPKIETIPSGSICYATTNRQTALQRLAPETDLTIVVGSEASSNAKRLVETAQRRGTTAYLVNDPNAIDPRWLENVKRISLTSSASTPEETTGAVVRRLEELGVAVVSEHEGILERVPKWKFPKNLLEAGKKKLDDTSRQTALGVETL Sbjct: 1 MTTEARTVVLASPRSFCAGVERAIEIVELALERFGAPIYVRKQIVHNTHVVARLEGEGAIFVDDLDAVPDGACVVFSAHGVAPSVRAEAESRGLDVIDATCPLVAKVHTEARRFAERGDTILLIGHSGHEEVEGTMGEAAG-IRLVESLADVDSLTVEDPSKVAYLTQTTLSVDETAEIIAALRRRFPKLRGPGGDDICYATSNRQEAIVEVAREADLVLVVGSRNSSNSRRLTEVAATAGTPAHLIEDAGQIRTEWLTGARVIGLSAGASAPPHLVEAVIAHLRGFGPVTVTERHTVEENVT-FSLPLVVRQPLGVLLAPFLERLRLGVDEL ZP_05048201.1 4-hydroxy-3-methylbut-2-enyl diphosphate reductase [Nitrosococcus oceani AFC27] Length: 363. Score: 1053. Identity: 42%. E-value: 1E-112. Query: 371 ASGKEESEGISLLLSKPRGFCAGVSRAVGIVEEALRIWGPPVYVKHSIVHNEVVCEAMRKKGAVFVEEISDIPRGAVAVFSAHGVSPAVRAEAEARQLQVVDATCPLVTKVHVYVKQKAEQGYHIILIGHKNHVEVIGTQGEAPGAVTVVESVEDVEQLSFSDSQKLFYATQTTLSLDDCGAIRQALIEKYPKIETIPSGSICYATTNRQTALQRLAPETDLTIVVGSEASSNAKRLVETAQRRGTTAYLVNDPNAIDPRWLENVKRISLTSSASTPEETTGAVVRRLEELGVAVVSEHEGILERVPKWKFPKNLLEAGKKKLD Sbjct: 35 APSNNRIKLMKVTLAQPRGFCAGVVRAIDIVEHALEIYGAPIYVLHEIVHNQHVVEDLQRRGVIFTEDLASIPAGSVTIFSAHGVSTAVVETAKKNDLQVIDATCPLVTKVHLQAKKYYRQGDELIIIGHAGHPEVEGTRGRVKGTVYVLDSVAEVENLAVKDPEHIAYVTQTTLSIDDTRDVVDALKKRFPKIHGPGLDDICYATQNRQNAVREMSKKVDILLVVGARNSSNSNRLREVGEQNGITAHLIQDAKDLDSSWFTSQSRVGITAGASTPEILVQGVLNELRSYGVEEVMDLDGVQESI-SFRLPTMLPRAKLRQKQ ZP_04940758.1 LytB protein [Burkholderia cenocepacia PC184] Length: 540. Score: 1037. Identity: 51%. E-value: 1E-110. Query: 382 LLLSKPRGFCAGVSRAVGIVEEALRIWGPPVYVKHSIVHNEVVCEAMRKKGAVFVEEISDIPRGAVAVFSAHGVSPAVRAEAEARQLQVVDATCPLVTKVHVYVKQKAEQGYHIILIGHKNHVEVIGTQGEAPGAVTVVESVEDVEQLSFSDSQKLFYATQTTLSLDDCGAIRQALIEKYPKIETIPSGSICYATTNRQTALQRLAPETDLTIVVGSEASSNAKRLVETAQRRGTTAYLVNDPNAIDPRWLENVKRISLTSSASTPEETTGAVVRRLEELGVAVVSEHEGILERVPKWKFPKNL Sbjct: 232 ILLAQPRGFCAGVDRAIEIVERAIAMHGAPIYVRHEIVHNKYVVEDLKKKGAIFVEELEEVPAGNTVIFSAHGVSKAVRDEADVRGLRIYDATCPLVTKVHVEVAKMRQDGVDIVMIGHKGHPEVEGTMGQVERGMHLVESVEDVQKLELADPERIALVTQTTLSVDDAAEIIGALKAKYPKIREPKKQDICYATQNRQDAVKFMAPQCDVVIVVGSPNSSNSSRLREVAEKRGVAAYMVDAPDQIDPAWVAGKRRIGVTAGASAPEVLAQAVIARLRELGVRNVRALDGIEENV-SFPLPRGL ZP_02537792.1 4-hydroxy-3-methylbut-2-enyl diphosphate reductase [Endoriftia persephone 'Hot96_1+Hot96_2'] Length: 389. Score: 1035. Identity: 47%. E-value: 1E-110. Query: 382 LLLSKPRGFCAGVSRAVGIVEEALRIWGPPVYVKHSIVHNEVVCEAMRKKGAVFVEEISDIPRGAVAVFSAHGVSPAVRAEAEARQLQVVDATCPLVTKVHVYVKQKAEQGYHIILIGHKNHVEVIGTQGEAPG-----AVTVVESVEDVEQLSFSDSQKLFYATQTTLSLDDCGAIRQALIEKYPKIETIPSGSICYATTNRQTALQRLAPETDLTIVVGSEASSNAKRLVETAQRRGTTAYLVNDPNAIDPRWLENVKRISLTSSASTPEETTGAVVRRLEELGVAVVSEHEGILERVPKWKFPK Sbjct: 4 IILANPRGFCAGVDRAIEIVQRALDMLGAPIYVRHEVVHNRFVVESLRQRGAIFVDELSDIPDGNTVIFSAHGVSQTVRQEAQRRDLRIFDATCPLVTKVHLEVARRCRDGYEVILIGHRGHPEVVGTMGQCRSKEESARIHLVVTPSDVEQLQISDSSRVAFVTQTTLSIDDTALVIAALQQRFPNIEGPKKNDICYATQNRQDAVKELAEQCDLVLVVGSPNSSNSNRLCEIARRHSTPAYLIDGAEDIDRSWLAGKARIGVSAGASAPEVLVERVLERLQEWGADQINEGAGKTEEVV-FSLPE C4DRE0 4-hydroxy-3-methylbut-2-enyl diphosphate reductase - Stackebrandtia nassauensis DSM 44728 Length: 422. Score: 1041. Identity: 44%. E-value: 1E-110. Query: 378 EGISLLLSKPRGFCAGVSRAVGIVEEALRIWGPPVYVKHSIVHNEVVCEAMRKKGAVFVEEISDIPRGAVAVFSAHGVSPAVRAEAEARQLQVVDATCPLVTKVHVYVKQKAEQGYHIILIGHKNHVEVIGTQGEAPGAVTVVESVEDVEQLSFSDSQKLFYATQTTLSLDDCGAIRQALIEKYPKIETIPSGSICYATTNRQTALQRLAPETDLTIVVGSEASSNAKRLVETAQRRGTTAYLVNDPNAIDPRWLENVKRISLTSSASTPEETTGAVVRRLEELGVAVVSEHEGILERVPKWKFPKNLL Sbjct: 115 RPRTVLLASPRSYCAGVERAIEVVERALERHGQPVYVRKQIVHNAHVVAELEKRGAVFVDELDQVPDGATVIFSAHGVSPAVRDDADSRGLAAIDATCPLVTKVHAEARRFADRGDTVVLIGHDGHEEVEGTMGEAPESMVLVESVADVERLRVPDPRRLAYLTQTTLAVEETEEIIAALRARFPALRGPGSDDICYATTNRQHAVAAIVDDCDLVLVVGSANSSNSRRLVELAERHGRMARLIDSAEDIELDWLTGADTVGLSAGASAPQILMDEVVETLAGFGPIDVVERVVTAED-QSFVLPREVR ZP_01874889.1 LytB protein [Lentisphaera araneosa HTCC2155] Length: 357. Score: 1005. Identity: 47%. E-value: 1E-106. Query: 374 KEESEGISLLLSKPRGFCAGVSRAVGIVEEALRIWGPPVYVKHSIVHNEVVCEAMRKKGAVFVEEISDIPRGAVAVFSAHGVSPAVRAEAEARQLQVVDATCPLVTKVHVYVKQKAEQGYHIILIGHKNHVEVIGTQGEAPGAVTVVESVEDVEQLSFSDSQKLFYATQTTLSLDDCGAIRQALIEKYPKIETIPSGSICYATTNRQTALQRLAPETDLTIVVGSEASSNAKRLVETAQR-RGTTAYLVNDPNAIDPRWLENVKRISLTSSASTPEETTGAVVRRLE-ELGVAVVSEHEGILERVPKWKFPK Sbjct: 44 KIQGKIMKLIMAAPRGFCAGVERALKIVDEALELLPHPIYVNHEIVHNSHVVEFYKKKGVIFVEEIDDVPDGSSFIFNAHGVPPSLVKASKERGMKIVDATCPLVSKVHFEAIRYAKQGYKIILIGHEGHPEVIGVMGEAPDAIYLVEKPEDVDDLEFTQDDKIAYITQTTLSVDDCAAVISSLKKRYPGVSEPKKADICYATTNRQEAVKQIAEKCDVFLIVGSPNSSNSNRLREVAKAGKGLDAYMVNCAEGLDPKWFEGKQTLGLSAGASTPEKIVSAVVDRLKAECGLIEVSEFISREEN-EHFALPK XP_002257762.1 LytB protein [Plasmodium knowlesi strain H] Length: 468. Score: 992. Identity: 53%. E-value: 1E-105. Query: 371 ASGKEESEGISLLLSKPRGFCAGVSRAVGIVEEALRIWGPPVYVKHSIVHNEVVCEAMRKKGAVFVEEISDIPRGAVAVFSAHGVSPAVRAEAEARQLQVVDATCPLVTKVHVYVKQKAEQGYHIILIGHKNHVEVIGTQGEAPGAVTVVESVEDVEQLSFSDSQKLFYATQTTLSLDDCGAIRQALIEKYPKIETIPSGSICYATTNRQTALQRLAPETDLTIVVGSEASSNAKRLVETAQRRGTTAYLVNDPNAIDPRWLENVKRISLTSSASTPEETTGAVVRRL-EELGVAVVSEHEGILERVPKWKFPKNLLEAGKKKLDD Sbjct: 123 SGGTPKEGEKILYLVSPRGFCKGVSRAIDTVEECLQMFKPPIYVKHKIVHNDIVCKRLEEKGAVFIEDINEVPDGNILIYSAHGISPQIRELAKKKKLIEIDATCPLVNKVHMYVQMKAKEGYKIILIGYKNHVEVIGTFNEAPESTYVVQNVEQIDDLPFTEKDKLFYVTQTTLSMDDCSLIVKRLKEKFPQIETIPSGSICYATTNRQTALNQICQQCDLTIVVGSQSSSNAKKLAYSSELRNTPAVLVNSVDDFDFSSLRDVKTIALTSAASTPEELTQKFVEVLTKEPFHYTLRLFEPVQENVPKWKLPKNLLGLIEERRRE YP_003160713.1 hydroxymethylbutenyl pyrophosphate reductase [Jonesia denitrificans DSM 20603] Length: 368. Score: 995. Identity: 46%. E-value: 1E-105. Query: 378 EGISLLLSKPRGFCAGVSRAVGIVEEALRIWGPPVYVKHSIVHNEVVCEAMRKKGAVFVEEISDIPRGAVAVFSAHGVSPAVRAEAEARQLQVVDATCPLVTKVHVYVKQKAEQGYHIILIGHKNHVEVIGTQGEAPGAVTVVESVEDVEQLSFSDSQKLFYATQTTLSLDDCGAIRQALIEKYPKIETIPSGSICYATTNRQTALQRLAPETDLTIVVGSEASSNAKRLVETAQRRGTTA-YLVNDPNAIDPRWLENVKRISLTSSASTPEETTGAVVRRLEELGVAVVSEHEGILERVPKWKFPKNLLEAGKKK Sbjct: 34 TGKRVLLAAPRGYCAGVDRAVIAVEKALEVHGAPVYVRKEIVHNKFVVETLTDRGAIFVNETDEVPEGARVVFSAHGVSPAVVASAQQRNLQTIDATCPLVTKVHKEAVRFASDDYDILLIGHDGHEEVEGTAGEAPDHIQVVNSPDEVDKVVVRDPDKVVWISQTTLSVDETMETVRRLRERFPTLQDPPSDDICYATQNRQVAMKKLAPHCDLVLVVGSTNSSNSVRLTEVALDAGARASYLIDYAKEIDETWLDGVETVGLSSGASVPEILVQDVLKFLADRGYADVQEVRTATEDLL-FSLPRELRADLKKA ZP_03150701.1 hydroxymethylbutenyl pyrophosphate reductase [Clostridium thermocellum DSM 4150] Length: 694. Score: 992. Identity: 28%. E-value: 1E-105. Query: 380 ISLLLSKPRGFCAGVSRAVGIVEEALRIWGPPVYVKHSIVHNEVVCEAMRKKGAVFVEEISDIPRGAVAVFSAHGVSPAVRAEAEARQLQVVDATCPLVTKVHVYVKQKAEQGYHIILIGHKNHVEVIGTQGEAPGAVTVVESVEDVEQLSFSDSQKLFYATQTTLSLDDCGAIRQALIEKYPKIETIPSGSICYATTNRQTALQRLAPETDLTIVVGSEASSNAKRLVETAQRRGTTAYLVNDPNAIDPRWLENVKRISLTSSASTPEETTGAVVRRLEEL---GVAVVSEHEG------ILERVPKWKFPKNLLEAGKKKLDDTSRQTALG--VETLV Sbjct: 1 MEIIVAKSAGFCFGVSNAVKTVNNLLENQKEPIYTYGPIIHNAQVVDLFTSKGVKKIDDIDEAEPNGHIVIRAHGVTPDIYKKISDKGLILEDATCPYVKKIHNLVKEKSEEGYKIIIVGDRNHPEVIGINGWCNNQAYIVDSVDDVEKFPTSD-EKVCVVAQTTITNEKWLEVNTALKKKFKNI--LKFDTICSATSRRQNEAEEIAKNVDMMIIIGGKNSSNTQKLYDICKKHCNLTYKIETSGDLPPVDIKKIKKVGISAGASTPDWVIEEVIKKMSELNKQGMVDILENDGEIDFANAFENSFVRIHAGDTVKGKIIGFNSNEVFVDLGYKADGII YP_002957672.1 4-hydroxy-3-methylbut-2-enyl diphosphate reductase [Micrococcus luteus NCTC 2665] Length: 368. Score: 986. Identity: 44%. E-value: 1E-104. Query: 370 PASGKEESEGISLLLSKPRGFCAGVSRAVGIVEEALRIWGPPVYVKHSIVHNEVVCEAMRKKGAVFVEEISDIPRGAVAVFSAHGVSPAVRAEAEARQLQVVDATCPLVTKVHVYVKQKAEQGYHIILIGHKNHVEVIGTQGEAPGAVTVVESVEDVEQLSFSDSQKLFYATQTTLSLDDCGAIRQALIEKYPKIETIPSGSICYATTNRQTALQRLAPETDLTIVVGSEASSNAKRLVETAQRRGT-TAYLVNDPNAIDPRWLENVKRISLTSSASTPEETTGAVVRRLEELGVAVVSEHEGILERVPKWKFPKNLLEAGKKKLDDTSRQT Sbjct: 35 PVSGEKR-----VLLAAPRGYCAGVDRAVVAVEKALEHHGAPVYVRKEIVHNRHVVDTLTERGVVFVDELDEVPEGALTVFSAHGVSPAVVEEAAQRNLRTIDATCPLVTKVHREAVRFAKQDKRILLIGHDGHEEVEGTFGEAPEHTTVINDVAEARTVQVEDPDNLIWLSQTTLSVDETLEIVSVLRERFPHLQDPPSDDICYATSNRQAAIKSISPECDLVIIVGSANSSNSVRLKEVAAEYGASRAERVDFANQVDESWFEGVATVGLSSGASVPEVLVQEVLALLAEYGYGQVDEVVTAEEDII-FSLPKELR-AELKRVGDESRSL XP_728969.1 (E)-4-hydroxy-3-methylbut-2-enyl diphosphate reductase [Plasmodium yoelii yoelii str. 17XNL] Length: 475. Score: 981. Identity: 54%. E-value: 1E-103. Query: 382 LLLSKPRGFCAGVSRAVGIVEEALRIWGPPVYVKHSIVHNEVVCEAMRKKGAVFVEEISDIPRGAVAVFSAHGVSPAVRAEAEARQLQVVDATCPLVTKVHVYVKQKAEQGYHIILIGHKNHVEVIGTQGEAPGAVTVVESVEDVEQLSFSDSQKLFYATQTTLSLDDCGAIRQALIEKYPKIETIPSGSICYATTNRQTALQRLAPETDLTIVVGSEASSNAKRLVETAQRRGTTAYLVNDPNAIDPRWLENVKRISLTSSASTPEETTGAVVRRLEELGVA-VVSEHEGILERVPKWKFPKNLLEAGKKKLDDTS Sbjct: 159 LYLVNPRGFCKGVSRAIETVEECLKTFKTNIYVKHKIVHNDIVCKDLENKGAIFIEDLNEVPDGSILIYSAHGISPQIKELAKKKKLIEIDATCPLVNKVHVYVKMKAKEGYKIILIGYKNHVEVIGTYNEAPDCTYIVENVEQVNNLNFTENQKLFCVTQTTLSVDDCALILNKLKEKYPNIETIPSGSICYATTNRQRALNKICTECDITIVVGSQSSSNAKKLVYSSQIRNTDAILINTINDLDFSILKNVKKIALTSAASTPDELTQQFVKVLTNPPYNYKLNIFNGVEEIVPKWKLPKELINMIKQKKEEQT XP_762798.1 4-hydroxy-3-methylbut-2-enyl diphosphate reductase LytB [Theileria parva strain Muguga] Length: 371. Score: 968. Identity: 56%. E-value: 1E-102. Query: 375 EESEGISLLLSKPRGFCAGVSRAVGIVEEALRIWGPPVYVKHSIVHNEVVCEAMRKKGAVFVEEISDIPRGAVAVFSAHGVSPAVRAEAEARQLQVVDATCPLVTKVHVYVKQKAEQGYHIILIGHKNHVEVIGTQGEAPGAVTVVESVEDVEQLSFSDSQKLFYATQTTLSLDDCGAIRQALIEKYPKIETIPSGSICYATTNRQTALQRLAPETDLTIVVGSEASSNAKRLVETAQRRGTTAYLVNDPNAIDPRWLENVKRISLTSSASTPEETTGAVVRRLEELGVAVV-SEHEGILERVPKWKFPKNL Sbjct: 37 EPQTPKKVYLVKPRGFCEGVSRAIRTVEEALRVFGPPIYVKHEIVHNEAVCNRLRARGVVFIEDLNLVPENSVLIYSAHGVSPEVKELAKTRNLVEIDASCPLVNKVHVYVKNKAKEGYKIVLIGHKNHQEIIGTSGEAPEAVTVVENVADVEKLDYPEGTKLYYVTQTTLSLDDCKEIKEALVKKYPQIETIPSGSICYATTNRQTAIHKVTEFVDLVLIVGSTMSSNAKRLVEAALNRNIRSYLVFDSNDVTEELVGSARNIALSSSASTPEDLTFAV