P13009 is a cross-reference for ZP_04871088.1, which is represented by YP_001591292.1 in NRDB40.
| Set | Shortcuts | Acc.No. | Identifier | Database | Description |
|---|---|---|---|---|---|
| NRDB | IBP | ZP_04871088.1 | 254037011 | RefSeq | methionine synthase [Escherichia sp. 1_1_43] |
| NRDB40 | IBP | YP_001591292.1 | 161617327 | RefSeq | B12-dependent methionine synthase [Salmonella enterica subsp. enterica serovar Paratyphi B str. SPB7] |
PSI-BLAST Results for YP_001591292.1 against NRDB40
Filtering conditions for the hit sequences
- E-value is less than
Matches:
[1-50][51-100] [101-150] [151-200] [201-250] [251-300] [301-350] [351-400] [401-450] [451-500] [501-550] [551-600] [601-650] [651-700] [701-750] [751-800] [801-850] [851-900] [901-950] [951-994]
Match Overview
| Score | E-value | Shortcuts | Acc.No. | Description | ||
|---|---|---|---|---|---|---|---|
  | - | IBP | YP_001591292.1 | B12-dependent methionine synthase [Salmonella enterica subsp. enterica serovar Paratyphi B str. SPB7] | |||
  | 2733 | 1E-200 | IBP | B9ZN58 | Methionine synthase - Thioalkalivibrio sp. K90mix | ||
| 2611 | 1E-200 | IBP | ZP_01044513.1 | 5-methyltetrahydrofolate--homocysteine methyltransferase [Nitrobacter sp. Nb-311A] | ||
| 2259 | 1E-200 | IBP | XP_002164385.1 | PREDICTED: similar to cobalamin-dependent methionine synthase [Hydra magnipapillata] | ||
| 2604 | 1E-200 | IBP | XP_002192722.1 | PREDICTED: 5-methyltetrahydrofolate-homocysteine methyltransferase [Taeniopygia guttata] | ||
| 2602 | 1E-200 | IBP | C1EAX2 | Predicted protein - Micromonas sp. RCC299 | ||
| 1696 | 1E-200 | IBP | ZP_04969909.1 | methionine synthase [Fusobacterium nucleatum subsp. polymorphum ATCC 10953] | ||
| 2031 | 1E-200 | IBP | YP_825433.1 | methionine synthase (B12-dependent) [Solibacter usitatus Ellin6076] | ||
| 1839 | 1E-200 | IBP | C4LIL8 | 5-methyltetrahydrofolate--homocysteinemethyltransferase - Corynebacterium kroppenstedtii (strain DSM 44385 / CCUG 35717) | ||
| 1851 | 1E-200 | IBP | NP_827843.1 | 5-methyltetrahydrofolate:homocysteine S-methyltransferase [Streptomyces avermitilis MA-4680] | ||
| 1937 | 1E-200 | IBP | YP_001274457.1 | methionine synthase [Roseiflexus sp. RS-1] | ||
| 1862 | 1E-200 | IBP | ZP_01085488.1 | putative methionine synthase [Synechococcus sp. WH 5701] | ||
| 1769 | 1E-200 | IBP | C3XLV5 | S-methyltransferase - Helicobacter winghamensis ATCC BAA-430 | ||
| 1639 | 1E-179 | IBP | ZP_01873173.1 | 5-methyltetrahydrofolate--homocysteine methyltransferase [Lentisphaera araneosa HTCC2155] | ||
| 1603 | 1E-175 | IBP | YP_003038791.1 | putative B12-dependent methionine synthase [Candidatus Hodgkinia cicadicola Dsem] | ||
| 1427 | 1E-155 | IBP | YP_001560351.1 | homocysteine S-methyltransferase [Clostridium phytofermentans ISDg] | ||
| 1402 | 1E-152 | IBP | YP_076329.1 | 5-methyltetrahydrofolate S-homocysteine methyltransferase [Symbiobacterium thermophilum IAM 14863] | ||
| 1358 | 1E-147 | IBP | ZP_02930588.1 | Methionine synthase [Verrucomicrobium spinosum DSM 4136] | ||
| 1302 | 1E-140 | IBP | YP_388607.1 | methionine synthase (B12-dependent) [Desulfovibrio desulfuricans subsp. desulfuricans str. G20] | ||
| 1302 | 1E-140 | IBP | ZP_01771753.1 | Hypothetical protein COLAER_00742 [Collinsella aerofaciens ATCC 25986] | ||
| 1245 | 1E-134 | IBP | B4DST3 | cDNA FLJ56487, highly similar to Methionine synthase (EC 2.1.1.13) - Homo sapiens PE=2 SV=1 | ||
| 1237 | 1E-133 | IBP | YP_001916863.1 | homocysteine S-methyltransferase [Natranaerobius thermophilus JW/NM-WN-LF] | ||
| 1203 | 1E-129 | IBP | B9KC48 | 5-methyltetrahydrofolate S-homocysteine methyltransferase - Thermotoga neapolitana (strain ATCC 49049 / DSM 4359 / NS-E) | ||
| 1193 | 1E-128 | IBP | YP_001681058.1 | methionine synthase, putative [Heliobacterium modesticaldum Ice1] | ||
| 1151 | 1E-123 | IBP | YP_860387.1 | 5-methyltetrahydrofolate--homocysteine methyltransferase [Gramella forsetii KT0803] | ||
| 1123 | 1E-120 | IBP | B4DST3 | cDNA FLJ56487, highly similar to Methionine synthase (EC 2.1.1.13) - Homo sapiens PE=2 SV=1 | ||
| 1100 | 1E-117 | IBP | ZP_02930588.1 | Methionine synthase [Verrucomicrobium spinosum DSM 4136] | ||
| 983 | 1E-103 | IBP | XP_001702462.1 | cobalamin-dependent methionine synthase [Chlamydomonas reinhardtii] | ||
| 983 | 1E-103 | IBP | C0FPZ7 | Putative uncharacterized protein - Roseburia inulinivorans DSM 16841 | ||
| 880 | 1E-91 | IBP | Q8BUC4 | Putative uncharacterized protein (Fragment) - Mus musculus | ||
| 784 | 2E-80 | IBP | ZP_01788142.1 | MetH protein [Haemophilus influenzae 3655] | ||
| 751 | 1E-76 | IBP | Q4SYB4 | Chromosome undetermined SCAF12111, whole genome shotgun sequence. (Fragment) - Tetraodon nigroviridis | ||
| 733 | 2E-74 | IBP | YP_590922.1 | methionine synthase (B12-dependent) [Candidatus Koribacter versatilis Ellin345] | ||
| 696 | 3E-70 | IBP | YP_002506189.1 | homocysteine S-methyltransferase [Clostridium cellulolyticum H10] | ||
| 692 | 7E-70 | IBP | XP_001702462.1 | cobalamin-dependent methionine synthase [Chlamydomonas reinhardtii] | ||
| 656 | 1E-65 | IBP | C0UX63 | Methylenetetrahydrofolate reductase - Thermobaculum terrenum ATCC BAA-798 | ||
| 653 | 3E-65 | IBP | YP_860387.1 | 5-methyltetrahydrofolate--homocysteine methyltransferase [Gramella forsetii KT0803] | ||
| 636 | 2E-63 | IBP | ZP_02081447.1 | hypothetical protein CLOLEP_02923 [Clostridium leptum DSM 753] | ||
| 637 | 2E-63 | IBP | C1F3L2 | Methylenetetrahydrofolate reductase - Acidobacterium capsulatum (strain ATCC 51196 / DSM 11244 / JCM 7670) | ||
| 636 | 2E-63 | IBP | ZP_01288844.1 | Methylenetetrahydrofolate reductase:Homocysteine S-methyltransferase [delta proteobacterium MLMS-1] | ||
| 615 | 7E-61 | IBP | ZP_02330511.1 | bifunctional homocysteine S-methyltransferase/5,10-methylenetetrahydrofolate reductase protein [Paenibacillus larvae subsp. larvae BRL-230010] | ||
| 611 | 2E-60 | IBP | ZP_02435545.1 | hypothetical protein BACSTE_01792 [Bacteroides stercoris ATCC 43183] | ||
| 611 | 2E-60 | IBP | XP_002116182.1 | hypothetical protein TRIADDRAFT_60203 [Trichoplax adhaerens] | ||
| 603 | 2E-59 | IBP | B6TK96 | Homocysteine S-methyltransferase 3 - Zea mays PE=2 SV=1 | ||
| 597 | 8E-59 | IBP | ZP_02444417.1 | hypothetical protein ANACOL_03741 [Anaerotruncus colihominis DSM 17241] | ||
| 595 | 1E-58 | IBP | YP_002572237.1 | homocysteine S-methyltransferase [Anaerocellum thermophilum DSM 6725] | ||
| 589 | 7E-58 | IBP | C4V3M8 | Homocysteine S-methyltransferase - Selenomonas flueggei ATCC 43531 | ||
| 580 | 8E-57 | IBP | Q4S116 | Chromosome 1 SCAF14770, whole genome shotgun sequence - Tetraodon nigroviridis | ||
| 569 | 1E-55 | IBP | C4XYV2 | Putative uncharacterized protein - Clavispora lusitaniae ATCC 42720 | ||
| 567 | 3E-55 | IBP | XP_001845705.1 | numb-associated kinase [Culex quinquefasciatus] |
Stacked Multiple Aligment
1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1
1 1 1 1 1 1 1 1 1 1 2 2 2 2 2 2 2 2 2 2 3 3 3 3 3 3 3 3 3 3 4 4 4 4 4 4 4 4 4 4 5 5 5 5 5 5 5 5 5 5 6 6 6 6 6 6 6 6 6 6 7 7 7 7 7 7 7 7 7 7 8 8 8 8 8 8 8 8 8 8 9 9 9 9 9 9 9 9 9 9 0 0 0 0 0 0 0 0 0 0 1 1 1 1 1 1 1 1 1 1 2 2 2 2 2 2 2 2 2 2 3
1 2 3 4 5 6 7 8 9 0 1 2 3 4 5 6 7 8 9 0 1 2 3 4 5 6 7 8 9 0 1 2 3 4 5 6 7 8 9 0 1 2 3 4 5 6 7 8 9 0 1 2 3 4 5 6 7 8 9 0 1 2 3 4 5 6 7 8 9 0 1 2 3 4 5 6 7 8 9 0 1 2 3 4 5 6 7 8 9 0 1 2 3 4 5 6 7 8 9 0 1 2 3 4 5 6 7 8 9 0 1 2 3 4 5 6 7 8 9 0 1 2 3 4 5 6 7 8 9 0
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The representative sequence for the query: MTSQDARWRCAYQAYALGAAKVICRLDKALASPSGKATEVGGKLNMSHVARCSLFRQHALCQYGSLRGALSGASVSSKVEQLRAQLNERILVLDGGMGTMIQSYRLHEEDFRGERFADWPCDLKGNNDLLVLSKPEVIAAIHNAYFEAGADIIETNTFNSTTIAMADYRMESLSAEINYAAAKLARACADEWTVRTPNKPRYVAGVLGPTNRTASISPDVNDPAFRNITFDQLVAAYRESTKALVEGGADLILIETVFDTLNAKAAVFAVKEEFEALGVDLPIMISGTITDASGRTLSGQTTEAFYNSLRHAEALTFGLNCALGPDELRQYVQELSRIAECYVTAHPNAGLPNAFGEYDLDADTMAKQIREWAEAGFLNIVGGCCGTTPEHIAAMSRAVAGLPPRQLPDIPVACRLSGLEPLNIGDDSLFVNVGERTNVTGSAKFKRLIKEEKYSEALDVARQQVESGAQIIDINMDEGMLDAEAAMVRFLSLIAGEPDIARVPIMIDSSKWEVIEKGLKCIQGKGIVNSISMKEGVEAFIHHAKLLRRYGAAVVVMAFDEQGQADTRERKIEICRRAYKILTEEVGFPPEDIIFDPNIFAVATGIEEHNNYAQDFIGACEDIKRELPHALISGGVSNVSFSFRGNDPVREAIHAVFLYYAIRNGMDMGIVNAGQLAIYDDLPAELRDAVEDVILNRRDDGTERLLELAEKYRGSKTDEAANAQQAEWRSWDVKKRLEYSLVKGITEFIEQDTEEARQQAARPIEVIEGPLMDGMNVVGDLFGEGKMFLPQVVKSARVMKQAVAYLEPFIEASKEKGSSNGKMVIATVKGDVHDIGKNIVGVVLQCNNYEIVDLGVMVPAEKILRTAREVNADLIGLSGLITPSLDEMVNVAKEMERQGFTIPLLIGGATTSKAHTAVKIEQNYSGPTVYVQNASRTVGVVAALLSDNQRDDFVARTRKEYETVRIQHARKKPRTPPVTLEAARDNDLAFDWERYTPPVANRLGVQEVEASIETLRNYIDWTPFFMTWSLAGKYPRILEDEVVGVEAQRLFKDANDMLDKLSAEKLLNPRGVVGLFPANRVGDDIEIYRDETRTHVLTVSHHLRQQTEKVGFANYCLADFVAPRLSGKADYIGAFAVTGGLEEDALADAYEAQHDDYNKIMVKAIADRLAEAFAEYLHERVRKVYWGYAPNESLSNDELIRENYQGIRPAPGYPACPEHTEKGTIWQLLDVEKHTGMKLTESFAMWPGASVSGWYFSHPESKYFAVAQIQRDQVTDYAFRKGMSVEDVERWLAPNLGYDAD
YP_001591292.1 B12-dependent methionine s MTSQDARWRCAYQAYALGAAKVICRLDKALASPSGKATEVGGKLNMSHVARCSLFRQHALCQYGSLRGALSGASVSSKVEQLRAQLNERILVLDGGMGTMIQSYRLHEEDFRGERFADWPCDLKGNNDLLVLSKPEVIAAIHNAYFEAGADIIETNTFNSTTIAMADYRMESLSAEINYAAAKLARACADEWTVRTPNKPRYVAGVLGPTNRTASISPDVNDPAFRNITFDQLVAAYRESTKALVEGGADLILIETVFDTLNAKAAVFAVKEEFEALGVDLPIMISGTITDASGRTLSGQTTEAFYNSLRHAEALTFGLNCALGPDELRQYVQELSRIAECYVTAHPNAGLPNAFGEYDLDADTMAKQIREWAEAGFLNIVGGCCGTTPEHIAAMSRAVAGLPPRQLPDIPVACRLSGLEPLNIGDDSLFVNVGERTNVTGSAKFKRLIKEEKYSEALDVARQQVESGAQIIDINMDEGMLDAEAAMVRFLSLIAGEPDIARVPIMIDSSKWEVIEKGLKCIQGKGIVNSISMKEGVEAFIHHAKLLRRYGAAVVVMAFDEQGQADTRERKIEICRRAYKILTEEVGFPPEDIIFDPNIFAVATGIEEHNNYAQDFIGACEDIKRELPHALISGGVSNVSFSFRGNDPVREAIHAVFLYYAIRNGMDMGIVNAGQLAIYDDLPAELRDAVEDVILNRRDDGTERLLELAEKYRGSKTDEAANAQQAEWRSWDVKKRLEYSLVKGITEFIEQDTEEARQQAARPIEVIEGPLMDGMNVVGDLFGEGKMFLPQVVKSARVMKQAVAYLEPFIEASKEKGSSNGKMVIATVKGDVHDIGKNIVGVVLQCNNYEIVDLGVMVPAEKILRTAREVNADLIGLSGLITPSLDEMVNVAKEMERQGFTIPLLIGGATTSKAHTAVKIEQNYSGPTVYVQNASRTVGVVAALLSDNQRDDFVARTRKEYETVRIQHARKKPRTPPVTLEAARDNDLAFDWERYTPPVANRLGVQEVEASIETLRNYIDWTPFFMTWSLAGKYPRILEDEVVGVEAQRLFKDANDMLDKLSAEKLLNPRGVVGLFPANRVGDDIEIYRDETRTHVLTVSHHLRQQTEKVGFANYCLADFVAPRLSGKADYIGAFAVTGGLEEDALADAYEAQHDDYNKIMVKAIADRLAEAFAEYLHERVRKVYWGYAPNESLSNDELIRENYQGIRPAPGYPACPEHTEKGTIWQLLDVEKHTGMKLTESFAMWPGASVSGWYFSHPESKYFAVAQIQRDQVTDYAFRKGMSVEDVERWLAPNLGYDAD
B9ZN58 Methionine synthase - Thio -----------------------------------------------------TAPQGGFPPGCTALPGHDNESMTATRNDIEKALKERILILDGGMGTTIQLYKLEEADYRGERFKDWESDLKGNNDLLSLTRPDIIEQIHNDYLEAGADIIEANTFNGTRIAMADYHMEDLVPELNRESAKLARKAADAWTEKTPDKPRYVAGILGPTNRTASISPDVNDPGARNVDFDTLVESYKEAAEALVEGGVDILLIETVFDTLNAKAAIFAVKTLEDELGKELPIMISGTITDASGRTLSGQTTEAFWNSVRHANPVSIGLNCALGAKEMRQYVEELSRIADTHVSAHPNAGLPNEFGDYDESPEQMAADVGPWAEQGLLNIIGGCCGTLPEHIRAMREAVEKFPPRKVPEIAPACRLSGLEPCNITDDSLFVNVGERTNVTGSRKFLRLIQNEEYDVALEVALNQVEGGAQIIDINMDEGMLESQDAMVRFLNLLAGEPDIARVPVMIDSSKFEIIEAGLKCVQGKAVVNSISMKEGEENFIKQAQLCRRYGAAIVVMAFDEDGQADNEDRRVEICTRAYRLLTEKVGFPAEDIIFDPNIFAVATGIEEHNNYGVDFIEATRRIKQDLPHALVSGGVSNVSFSFRGNEPVREAIHAVFLYHAIKAGMDMGIVNAGQLAVYDDIDEKLKEAVEDVVLNRRDDATERLLDLSEEYKGQGG--GKKEENLEWREWEVTKRLEHSLVKGIDTYVVEDTEEARQQYDRPIQVIEGPLMDGMNVVGDLFGEGKMFLPQVVKSARVMKKAVAHLIPYIEAEKTGTENNGKILMATVKGDVHDIGKNIVGVVLQCNNFEVIDIGVMQPGAEILKAAKEHDVDVIGLSGLITPSLEEMANFAADLEREGMTTPLMIGGATTSRAHTAVKIEPNYSGPVVWVKDASRAVGVAQSLISPELRENYAAEIREEYEKLRVQNAGRKKKTQWVTLEKARANKPQIDWSSYTPTKPKALETDKLPFDLNEVRNFIDWTPFFHSWQLHAAYPRILDDEKVGEEARKLFKDGQEMLDRMIEEKWVTLRGVVGFFPANTVDDDIEVYTDESRSKVLKKLHHLRQQTEKRGQPSHSLADFLMPKEAGGPDYLGAFAVSAGGDVDAKAEEYEKANDDYHAILVKSLADRLAEAFAECMHQYVRKHYWGYVPDEALENEDLIDEKYQGIRPAPGYPACPEHTEKGTLWELLQADEHADMTLTESYAMLPVSAVSGWYFAHPESRYFGLGKVNRDQVEDYAKRKGMSFEEAERWLAPNIGYD--
ZP_01044513.1 5-methyltetrahydrofolate-- --------------------------------------------------------------------TRVTNSSNPIADKFRALARERILVLDGAMGTMIQDRGFDEAAFRGERFKDFHRDVRGNNDLLILTQPQAIEDIHTQYLRAGADLVATNTFSSTSIAQADYDMADLVYDLNREGARLARSAAEKVSAED-GKPRFVVGAIGPTNRTASISPDVANPGYRAVTFDDLRKAYGEQINGLLDGGADLLLVETIFDTLNAKAALYAIAEIGEQRGIDIPVMISGTITDKSGRLLSGQLPEAFWHSVRHAGPITIGFNCALGAEDLRAHVAEIGRVADTLVCAYPNAGLPNEFGQYDESPDYMARLIGEFAQTGLVNVVGGCCGTTPDHIAAIAAAVAPHKPRVVPVIAPRLRLSGLEPFSLTSDIPFVNVGERTNVTGSARFRNLIKAGDYAAALDVARNQVENGAQIIDVNMDEGLLDSEAAMVTFLNLIAAEPDIARVPVMVDSSKFSVIEAGLKCLQGKPVVNSISLKEGEEKFLHEARIARRHGAAVVVMAFDETGQADTCQRKMEICKRAYDILVEQVGFPPEDIIFDPNVFAIATGLEEHNNYGVDFIEATRWIRQNLPHAHISGGVSNLSFSFRGNEPVREAMHSVFLYHAIKAGMDMGIVNAGQMVIYDDIDPELRQVCEDVVLNRDPDAGERLLNLAEKFRGQGRQA--KEADLSWREWPVEKRLSHALVNGITEYIEQDTEEARQSADRPLSVIEGPLMAGMNVVGDLFGDGKMFLPQVVKSARVMKQAVAYLMPFMEEEKARNTSAGKILLATVKGDVHDIGKNIVGIVLQCNNYEVIDLGVMVPAAKIIETAKAEKADIVGLSGLITPSLDEMGYFAAELERQGLNLPLLIGGATTSRVHTAVKIDPNYNGPVIHVNDASRAVGVVASLMSPERREAYAAGVRAEYAKISAAHFRAQQDKKRLPLATARANAVPIDWSSYRPVKPTFLGTKAFDYPLEELVEVIDWTPFFQVWELAGRFPAILDDKVVGETARALYDDARKMLDRIVTEKWFTASGVIGFWPANRIGDDIAVYGDESRTTQIATYHTLRQQLEKRGRHNAALADFIAPKETGIADYIGGFAVTAGLGEDEIAARFKNANDDYSSILVKALADRLAEAFAERMHQRVRTEFWGYAPDEALTNDQLIREEYVGIRPAPGYPAQPDHTEKATLFRLLDATRATGVELTESFAMWPGSSVSGLYYSHPESQYFGVGKIERDQVEDYAARKGMEVAEIERWLASILNY---
XP_002164385.1 PREDICTED: similar to coba ----------------------------------------------------------------------------TRAQELPGILASRIAILDGAMGTMIQRFGYAGPGSQGDRFKDFPKDVKGNNELLSLTRPDVITDIHEAYLAAGADMIETNTFGATTVAQADYDMADLAIEMNFVSAKLARAACDKF--STPEKPRFVCGALGPTPKTASISPDVNDPGARNVTFEELRAAYYAQTKALVEGGADVILVETIFDTLNAKAALFAVDEYFEASGERLPIIISGTVTDASGRILSGQTVTAFWHSVRHAQPLAIGLNCALGAALMRPYIQELNKVTDTFISCYPNAGLPNSDTGFDETPDVTSRLVREFAEEGLVNIVGGCCGTTPDHIGAIAHAVNPIATRNVQPAPKPMLLSGLEPIIIDSSSLFVNVGERTNVTGSKAFARMILNGQFEEALAVARQQVENGAQIIDINMDEAMLDSQAAMVRFLNLIASEPDISRVPIMIDSSKWSVIEAGLRCVQGKAVVNSISMKEGLDEFKRQAKLLRRYGAAAVVMAFDEKGQADTYQRKVEICERAYRVLVDEVDFPPEDIIFDPNIFAIATGIEEHNNYAVDFIEATRWIKQNLPGAKVSGGVSNVSFSFRGNDPVREAIHTVFLYHAIKAGMDMGIVNAGMVGVYDDLEPTLRERVEDVVLNRREDAGERLVEIAETAKSGAKDESKKLEWRGTPEAPVAQRLSHALVHGITDFITEDTEEALAKGGRPLHVIEGPLMDGMNVVGDLFGQGKMFLPQVVKSARVMKSAVAHLLPYIEAEKLAAKAKGKIVIATVKGDVHDIGKNIVTVVLQCNNFDVVNMGVMVPCHEILAKAKEEGADIIGLSGLITPSLEEMQYVAGEMQKRSRNIPLLIGGATCSRVHTAVKIAPNYEGPVVYVPDASRSVSVAQSLLSESAAAYIAELNADYDKVRHQHANKKQTPLW--PLAKARANKAPIDWSAHQPTVPKFIGRRVFNFDLTELAKYIDWAPFFQTWDLAGPFPAILKDEVVGTEAVRVYSDGQRMLKRLIEGRWLTANAVVALYPANTVDDDIEFYTDESRSEVAMTWYGLRQQTEKVMRPSRCLADFVAPKGVK-ADYAGMFAVTAGIGVDKKEKYFLDDHDDYSAIMLKAIADRLAEAFAECLHHRVRTDLWGYAAGESLSNEDLIGEKYKGIRPAPGYPACPDHSVKKDMFALLQCEE--------------------------------------------------------------------
XP_002192722.1 PREDICTED: 5-methyltetrahy ---------------------------------------------------------------------------KSVEDEIESILQERIMVLDGGMGTMIQQHALTEEDFRGHEFKDHSRPLKGNNDLLSITQPDIICDIHKEYLLSGADIIETNTFSSTRVAQADYGLEHLAYRLNRVSAQVARKAADTVTAET-GIRRYVAGAMGPTNRTLSVSPSVERPDYRNITFDELVEAYTEQAKGLLDGGVDILLVETIFDTANAKAALFALQMLFEEEYASRPIFVSGTIVDKSGRTLSGQTGEAFVVSVSHSKPLCIGLNCALGAVEMRPFIETIGKCTTAYIICYPNAGLPNTFGGYDETPEVTAKHIENFALDGLVNIVGGCCGTTPAHIRKIAEAVKFCKPRVPPSLSEGMLLSGLEPFRIGPYTNFVNIGERCNVAGSRKFAKLIMAGNYEEALSVAKLQVEMGAQILDINMDDGMLDGPTAMTKFCNLISSEPDIAKVPLCIDSSNFSVIEAGLKCCQGKCIVNSISLKEGEEDFLEKARKIKLYGAAVVVMAFDEVGQATETETKIAICSRAYHLLVGKVHFNPNDIIFDPNILTIGTGMEEHNLYAINFINATKTIKETLPGARISGGLSNLSFSFRGMDAIREAMHGVFLYHAIKYGMDMGIVNAGNLPVYDDIHKELLQLCENLIWNKDPDATEKLLHYAQNH---AQGGKKVVQTDEWRKGSVEERLEYALIKGIEKYVIADTEEAREKYPRPLNVIEGPLMNGMKIVGDLFGAGKMFLPQVIKSARVMKKAVGHLIPYMEKEREERRAKGTIVLATVKGDVHDIGKNIVGVVLGCNNFRVIDLGVMTPCDKILRAAVENKADIIGLSGLITPSLDEMIFVAKEMERLAIKIPLLIGGATTSKTHTAVKIAPRYSAPVVHVLDASKSVVVCSQLLDDSIKDDFFEEILDEYEEIRQEHYESLKERRYLSLQQARRKGFQNNWLSHIPVKPKFIGTKVFEYDLRRLVDYIDWKPFFDVWQLRGKYPNIFNDKTVGEEAKRVYNDAQDLLKMLINEKKLQARGVVGFWPARSVQDDIHLYAVEGSSEPIAKFYGLRQQAEKDTDPYYCLSDFIAPLDSGICDYLGLFAV-ACFGVDDLCSEFRKQEDEYNIIMVKALGDRLAEAFAEELHERVRREFWAYSSSEQLDLSGLRKIKYEGIRPAPGYPSQPDHTEKLTMWKLANIEETTGIGLTESLAMIPASAVSGLYFSSPNSKYFAVGKICRDQVEDYALRKNLSVVEVEKWLEPILGYDAE
C1EAX2 Predicted protein - Microm -----------------GAMLVAYVLNKRGAQPPRPKAVAAGQGASYAEMYPEVQPKANLPPVPKYAKWVDPVKPTAAFDQINKIMKERIMVIDGAMGTAVQKYKLSEDDFRGERYKNHTHDLKGNNDVLVITRPDVIEEIHTAYLAAGADIIETNTFNSTMISQADYELDEEVYLLNKTAAQLAKKCCVEFTKKNPAKPRFAAGAVGPTNKTLSVSPSVENPAFRGCTYDEIVEAYYEQVEALIDGGVDVLLVETIFDTLNAKAAMFAIDMYFEKWGQKIPVFVSGTIVDNSGRTLSGQTNEAFWNSMSHSKPIAIGLNCALGAKDMVPYIENLSRVADCWVFCYPNAGLPNAMGGYDQKGAEMAEDCRVFPEKGLINAIGGCCGTTDEHIKCLADMVATYKPRERHDVPDIMRLSGLEPFNYAPNEKFINLGERCNVAGSTIFKKAIVDGNYEKALAIALKQVENGAHVIDVNMDDGLIDGESAMTKFVNLMVSEPDVAKVPFMIDSSKFHVVEAGLKCSQGKCIMNSISLKGGEEEFLNQAKIVKRHGAAVVVMAFDEEGQAATEAEKVRICCRAYKLLVEKVGFNPQDIIFDPNILTIGTGMEEHNNYGVDFINATREIKRLCPGCKISGGVSNLAFSFRGNEPVRRAFHSAFLYHACKAGMDMGIVNAAQVDVYEKIDKELLEYVEDVLLNRCTNATERMLEFAATLDPKSKPTALRKKAKAWRNQTVGKRLEHALVKGIDEFCIADTEECRTNGKTPLEIIEGPLMDGMNVVGDLFGAGKMFLPQVIKSARVMKKSVGHLIPFMEEEKREASNAGVFLIATVKGDVHDIGKNIVAVVLGCNNFKVIDIGVMCPKDKIIDALKEHNADICGLSGLITPSLDEMVDMAKAMEAEGMKIPLLIGGATTSKMHTAVKLAPNYSGGVVHVLDASRAVPVAQTLMDQNKRGEYLDDINETYAEMREEFYAGLEDRKYLTLGQARDTAVDFKSKEHTPVTPQFTGVKALDVPIADVIDYIDWNPFFQVWQLRGRYPNIFNDETVGAEAKKLYEEAQRMLKSIMDNKRLKLNGIIGFYPANSVGDDIEVYADESRTTKTHTFHTLRQQAEKDVEPYMALSDFIAPKDSGVKDYLGMFVATAGIGLHELTAEFKAANDDYSYIMAEALADRLAEAFAELMHEKVRKEHWGYAKDEKFNCEDLLKVKYQGIRPAPGYPSQPDHTEKATMWDLMKVQEEIGVELTESFAMLPSASVSGLYFAGKCSQYFNVGKITADQVKEYADRKGQDFKTAEKWLSPILSYE--
ZP_04969909.1 methionine synthase [Fusob --------------------------------------------------------------------------------EFEKELKERILVLDGAMGTVLQKYELTPEDFNG---------AKGCYEILNETRPDIIFEVHKKYIEAGADIIETNSFNCNAISLKDYHLEDKVYDLAKKSAEIARDAVKE-----SGKKVYVFGSIGPTNKSLSF-PVGDVPYKRAVSFDEMKEVIKVQVAGLIDGGVDGILLETIFDGLTAKAALLATEEVFEEKNVKLPISISATV-NRQGKLLTGQSMESLIAALDRDSVTSFGFNCSFGAKDLVPLVIKIKELTTKFVSLHANAGLPNQNGDYVETAQKMRDDLLPLIENQAINILGGCCGTSYDHIRAIAEMVKGQKPRVLPK-ENLLETCLSGNEIYNFNDKFTWVGERNNISGSKLFRTMIEEHNYLKALEVARQQIDAGAKVLDINVDDGILDSVEEMKNFLRVLQNDSFIAKVPIMIDSSDFAVIEEGLKNTSGKAIVNSISLKEGTEEFLRKAKIIRKYGASIVVMAFDEKGQGVSAERKIEICQRAYD-LLKSIGVKNSDIVFDPNILSVGTGQEADRYHAREFIKTIDYIHENLKGCGVVGGLSNLSFAFRGNNVLRAAFHHIFLEEAVPRGFNFAILNPKEKAPQWTDEE------------REKIKSFIFGDSTDMEALLSLNLVKKKEDAQIFAETPEDKIRKALIQGGSESLQEVIGDLL-KKYKALEILENILMSAMQEIGRLFEQGELYLPQLIRSASVMNNCVDILTPYLEKVDK-TSSKGKILMATVDGDVHDIGKNIVGTVLECNGYEVIDLGVMVPREKIVETAKEINADVVTLSGLISPSLKEMERVADLFQKVGMQVPVLIAGAATSKLHTGLKVLPNY-DYSLHVTDAMDTITVVSQLL-STKRKDFLETKQTQLRKIYMDNNSNQPEEKKVLPEVKK----------TVSYIPKVLGKQFLSLPVEIFKDTLKWDIALYALRVRNTP----------EEEKTLNDLKKI--YEKLIEEKVEFRAAYGYFRC----------------KKTETFLEMEGMTFEVSPN---LAQYI-----EKEDYVGGFVISVGSKI--------FKDDKYLGLLETLLCNAIAETASEYMETRVTEDIVPTFL-----------------RPAVGYPILPDHSLKKVVFDLIDGER-TGAKLSPAFAMSPLSTVCGFYLCNDNAKY--------------------------------------
YP_825433.1 methionine synthase (B12-d -----------------------------------------------------------------------------RQKALNDSLEQRVLVLDGAMGTMIHQAPLSIE--------TDYLGRENCPEILNVTRPDVIQDIHRQYLEAGADIIETNTFGGTRIALADNKLEERAYELNFAAAKLAREVADQF--STAAKPRFVAGSIGPTNKDLNIT--------GSTTFPEIKAAYYEQAKGLVEGGADYLLIETCFDTGSLKAGLVAVEQLGRELAIQIPVVASVTI-ERTGTMLGGQQIDALYASIGNHELLGVGMNCATGPDLMTDHIRTLNEMSAHRISCYPNAGLPNAEGKFGETPDSLAAQLEKFANQGWLNFVGGCCGTTPAHIQAIAQMIQGKRPRATPASKHRAYYSGIDLVEAEDSNRPLLVGERTNVIGSRLFKNLIADEKWEEATDIARRQVRNGAHVIDVCLQSTD---REELEDIRPFYEKLIRKIKAPIMIDTTDPKAVELALTYCQGKSIINSVNLEDGEEKFERLCPIAKLYGAALVVGSIDEDAQAFTRERKVAVAERSYRLLTEKYGIPGEDIIIDPLVFPCATGDVNYIGGAVETIEGIRLVKQALPYAKTVLGISNISFG--LPAAAREVVNSVFLYYCTKAGLDLAIVNAEKLERFASIPEEERRLAEHLLFNTPPAGAEDLRTAAEDWRAQSPEQAGARVKKAAADMPLDQRLANYIIEGTKDGLIADLDRKRAEGATPLEIINGPLMAGMSEVGRLFNNNELIVAEVLQSAEAMKAAVNHLEQFMEKAD--TAARGKVLLATVKGDVHDIGKNLVEIILANNGYEVINLGIKVPPDVLIQAFREHMPDAIGLSGLLVKSTQQMVITATDLKAAGIDVPLLVGGAALSEKFTRTKIGPAYSEAVCYAKDAMTGLSLMNRLMDPAEREALIA----TSTTLEAPAAVEAPAEPLGPLSTRRSRKVRTEL-----PVPPAPYLERKVRDVPNLADVWSYINPFMIYGRHLGYKGNFEKALAEHEEKALELFHNVEELKHEAAQFMHVKAVWQFFEAERDGNAIHLFAPGGASPIHTFRFGRQRRED-----GLCLSDYILDSPDGKRDHLALFVTTAGAGIRERSEQWKKAGEFFKAHAIQALAIETAEATAEWLHRRIRED-WGFPDPPTTTMHDRFTSKYHGKRYSFGYPACPNLDDQQGVWKLINPDD-IGVKLTEGMMMEPEASVSAIVFHHPDCAYFTADEGESEA----------------------------
C4LIL8 5-methyltetrahydrofolate-- --------------------------------------------------------------------------LNPKKSEFLQALHDRVLIGDGAMGTQLQAIDLDLDADF--------HGLEGCNEILNITRPDILADIHRRYFEAGADAVETNTFGCNLPNFADYGIEDRIEEIAYAGTQIARSVADDMGPGREGMKRFVLGSLGPGTKL---------PTLGNAPFSDLRDAYTEAAHGLVRGGADAILIETAQDLLQVKAAVHGVQQAFDDYGTTLPIMCHVTV-ETTGTMLLGSEIGAALTALERLGIDVIGMNCATGPDEMNEHLRYLSAHAPMPVSVMPNAGLPENGAVYPLTPDELAAASVHFVRDYGLSMVGGCCGTTPEHITAVRDAVIGSPDSQRHHDFDDNVSSLYSTVPLTQDTGITMIGERTNSNGSKAFRTAMLEGDWNKCLDIAKAQTRDGAHMIDLCVDYVGRDGTQDMAELA---SRLATNSTLPIMLDSTEPDVIRMGLEHLGGRCAVNSVNFEDGDSRYDRIMTLVKKHGAAVVALTIDEEGQARTAEKKVEIAERLIADITTRWGLRESDIIVDCLTFPISTGQVETRRDGIETINAIREITSRHPDIHTTLGLSNISFG--LNPAARQVLNSVFLNECIEAGLDTAIAHSSKIVPMNRIDDDQRDVALDMVYDRRDEDYDPLQTFMELFQGVSAADAKDARAEALQALPLFKRLAQRIIDGEKNGLEADLDLARDEK-DPLEIINQDLLAGMKVVGDLFGSGQMQLPFVLQSAETMKAAVSHLEQFMEATDDS-ASKGKIILATVKGDVHDIGKNLVDIILSNNGYDVVNLGIKQPISNILHAASEHQADVIGMSGLLVKSTVVMKDNLLEMNSAGANYPVLLGGAALTRTYVENDLDELYQGDVHYARDAFEGLNLMDQIMSMKRGSQRKKKEERKARHERSRKIAAKRKAESAPAVIPDRSDVATDTPIATPPFWGTRIVKGL--PVRDYLTCLDERALFMQWGLRGTRGGPSYDELVETEGR---PRLRAWINDLKAEGILNHSAVYGYFPAVSEGNTVHILEPDPTAQPVTSFEFPRQQRGRF----LCIADFIRSRDEGHTDVFPLQLVTMGQSIADKANVLFKDNHYREYLELHGIGVQLTEALAEYWHSRVRAEL-AFADGTHAGDDDGTEDRYRGARYSFGYGSCPDLESRRALVDLLRPER-IGVELSEELQLHPEQSTDAFVLYHPEAKYFNV-----------------------------------
NP_827843.1 5-methyltetrahydrofolate:h -------------------------------------------------TAVALQGASSMASLPNPSPSSASAASRSRTDALREALATRVVVADGAMGTMLQAQDPTLEDFE---------NLEGCNEILNLTRPDIVRSVHEAYFAVGVDCVETNTFGANHSALAEYDIADRVFELSEAGARLAREVADEFGTGD-GRQRWVLGSIGPGTKL---------PTLGHVGYGTLRDGFQANAEGLIAGGADALIVETTQDLLQTKTSVLGARRAMDATGVDLPLLVSMAF-ETTGTMLLGSEIGAALTALEPLGIDMIGLNCSTGPAEMSEHLRYLTRHSRIPLLCMPNAGLPKDGAHFPLGPEGLADAQENFVRDYGLSLVGGCCGTTPEHLRQLVERVRGVEPTERRPQPEPGAASLYQTVPFRQDTAYMAIGERTNANGSKKFREAMLDARWDDCVEMARDQIREGAHMLDLCVDYVGRDGVADMEELAG---RFATASTLPIVLDSTEVDVLRAGLEKLGGRAVINSVNYEDGDSRFAKVTRLAQEHGAALIALTIDEEGQARTVETKVAIAERLIEDLTTNWGIHESDILMDCLTFTICTGQEESRGDGIATIEAIRELKRRRPDVQTTLGLSNISFG--LNPAARILLNSVFLDECVKAGLDSAIVHASKILPIARFDEEQVTTALDLIYDRRSEGYDPLQKLMALFEGATTKSLKAGKAEELAALPLDERLKRRIIDGEKNGLEADLDAAL-QDRPALDIVNETLLDGMKVVGELFGSGQMQLPFVLQSAEVMKTAVAHLEPHMEKSDA--EGKGTIVLATVRGDVHDIGKNLVDIILSNNGYNVVNLGIKQPVSAILDAAEEHRADVIGMSGLLVKSTVIMKENLEELNQRGLDYPVILGGAALTRAYVEQDLHEIYQGEVRYARDAFEGLRLMDALIGVKRGVPGAALPELKQRRVRAAAVEVEERPE----EGAVRSDVATDNPVPAPPFRGTRVIKGIQ--LKEYASWLDEGALFKQWGLARTGDGPTYEELVESEGR---PRLRGLLDKLQTENLLEAAVVYGYFPCVSKDDDLIILDEQGNER--TRFTFPRQRRGR----RLCLADFFRPEESGERDVVGLQVVTVGSRIGTETAKLFEANSYRDYLELHGLSVQLAEALAEYWHARVRSEL-GFAGEDPDRMEDMFALQYRGARFSLGYGACPNLEDRAKIAALLEPER-IGVHLSEEFQLHPEQSTDAIVIHHPEAKYFNA-----------------------------------
YP_001274457.1 methionine synthase [Rosei -----------------------------------PHAGAWGFL--LHKRESAIIAPASPIITCRQFGYEVSRGVSLKKPTYLEALRERVLIYDGAMGTSIDTFHLTAADYGGE-------NTFGARDYLVMTRPDVIEQIHTSFLEAGADVLETCTFQSTRIRLEEWGLADQTHAINVAAARLARRVADAFEARD-GRPRYVAGSMGPTGKL----PSSDDPSLSDITFDQLSDIFYEQAVALIEGGVDVLLVETSVDILEVKAALDGIRRAKADLNRPDVAVQAQVFLDLSGKMLLGTEVPALVATLEAMPVDVIGLNCSTGPEHMREAIRYMTRHSRKPISCIPNAGLPNGETVYPMEPEPFARILGEYVHEYGVAVVGGCCGTRPAHIRRLRQVVGAAPPKVRDIEYIPSVSSGVRAAALRQEGTLTIIGERVNTLGSRKVKRLLLNDDYDGVLEVAREQVDSGSHILDVCVAMTERSDEREM--MVRLLKKLTMNIELPLAIDTTEADVLNAALAIYPGRAIVNSVSLEGGRDKIDRTMPLVARYGAATIAMTIDEEGMAHTAERKLAIARRIAQIAQDEYGVPPEALIFDVLTFPITTGQPELRRAAIETIEGIRLVKQHIPGCFTTLGVSNLSFG--VAPYARAALNSVFLKHAVDAGLDTAIINPAHVMPYAEIPPEQIRVCEDLIFDRDEQALARFIQFFEEHGSAAKTERVDPTAAQRVHWKIVHRKKEGIEQDIDTVIAERIREAHDSALDPADVLNTVLLPAMKEVGDLFGAGQLILPFVLQSAEVMKKAVAHLEQYLEKLEGVT--KGKIVLATVYGDVHDIGKNLVHTILANNGYTVYDLGKQVPINTIIEKAVEVNADAIGLSALLVSTSKQMPLCVQELHRRGLKFPVLVGGAAINKQYGQRDDHTPYEPGVFYCKDAFEGLETVDALVDPSTRATFIERTKAE--AAEALGKKQRGRVALAELGRATLSDVRTDVPVPTPPFWGARVLTRIK--LADVVECLDRNALYRQWG---------AKNAKGEEWEHLKADVRDLIREAERDGWLEPKVVYGYYPCQSDGHEVIVYDPGAQPRELTRFVFPRQPERE----RLCLADYFRSRESGEYDVVGLQIVTMGRKVDDLTETLQQSGDYSRAYFIHGLGVSLAEALAEYTNRLIRRQ--------------LGLKGTQGKRYSWGYPACPDLEEHEKLFRVLPAAE-IGVTLTEAWQLVPEQSTAAIVIHHPEAKYFSIGSARERAEEDVAE----------------------
ZP_01085488.1 putative methionine syntha --------------------------------------------------------------VGSAAAARTGTGRI----GFLEHLHRPVVVFDGATGTSLQQMDLSAEDFGG-------AALEGCNENLVFTRPDAVQAVHAQFLEAGCDVIETDTFGAASIVLAEYGLEDQAFALNQRAAELAREMADRY--STPTKPRFVAGSMGPTTKL---------PTLGHIDFDTMKASFREQAAGLLAGDVDLFIVETCQDVLQIKAALQGLEEAFEAAGERRPLMVSVTM-ETTGTMLVGSDIAAVVSILEPFAIDVLGLNCATGPEQMKEHIRYLSEHSPFVISCIPNAGLPENVGGYRLTPLELRLQLLHFVEDLGVQVIGGCCGTTPSHIAALAERLPQHRLKRPALQWEPAAASIYGVTPYHQDNSFLIIGERLNASGSRKVRDLLNAEDWDGLVALARGQIKENAHVLDVNVDYVGRDGEKDMH---DLVSRLVTNVNLPLMLDSTEWQKMEAGLKVAGGKCILNSTNYEDGDERFFKVLELARRYGAGVVVGTIDEEGMARTAERKFAIAQRAYRDALE-YGIPAHEIFYDPLALPISTGIEEDRRNAAATIEAIRLIRENLPGVHVVLGVSNVSFG--LSPAARIVLNSVFLHECCEAGLDAAIVSPAKILPLAKITEEHQQVCRDLIEDRRRFESEAEAAICTSLFEGVSAKEARASGPSLADLPVEQRLRQHIIDGERIGLEPALQEALAS-YPPLQIINTFLLDGMKVVGELFGSGQMQLPFVLQSAETMKAAVAFLEPHMEKVDGVSSAKAKFLIATVKGDVHDIGKNLVDIILTNNGYEVINLGIKQGVEAIIEAQHLHQADCIAMSGLLVKSTAFMKDNLQAFNEAGITAPVILGGAALTPRFVQKDCRSVYNGQVIYGRDAFADLRFMDALSEARKWDDRLGFLAGAPAGLLEAEPEPAAEPRAAGAEAASPDDQATPATASAPEVTSHRSIQEGEIPLDEVFAYLDRNALFAQWQLR-KSQDQSRQAYEAMLAEKAEPVLQSWIERCRQEVLLTPRVAYGYFPCGRDGNALVVFDPEGSERELGRFELPRQR----GGNRYCIADFFRDLSDGRPDVLPMQAVTMGERASAYARELFAADRYTDYLYFHGLGVQMAEALAEWTHARIRREL-GFAAEEPAALRDVLAQRYRGSRYSFGYPACPNVADSRQQLAWLDTGR-IGLTMDESDQLDPEQSTTALVALHSLARYFSA-----------------------------------
C3XLV5 S-methyltransferase - Heli ---------------------------------------------------------------------------------LRNCIKERVLILDGAMGTEIQKHNIQTWGVNAKGEKL-----DGCSEALNLYAKDIIKAIHTSYLQAGANILKTNTFGVMPWVLAEYGLEEHCKEIAKTGVELAKECIKKHSLKNQNNALFVAASLGPGTKL---------PSLGHITYDSMEEGYALCVEGFKEADADVILLETAQDPLQIKAALNAIKNTAPE----IPIMVSVTI-ETTGTMLIGTDITTLFHILEPYDLLSLGINCGLGPDLAHKHLVTLSEVCKFPISIHTNAGLPENRGGYPMDAEEFSTIEKSFLEIPGVAFLGGCCGTTPEHIRQLVQKTQSIIPKAPKCTYQPSITSLFEAKELKQFPAPLLIGERSNATGSKAFRELLLNEDYEGALSVGSAQVRSGAHCLDLSVAFAGRDESKDMQ---ELITRYATKITLPLMPDSTQVNALEIALKHIGGRAIINSANLEDGITKFDKVASLAKKFGAALICLTIDEEGMCKTFERKIACAKRMMERAITIHNLREEDIIFDPLTFTIGSGDAEYFDAGMQTLNTIKELSKLYPKAGTTLGLSNISFGLSKEG--RICLNSIFLHHAIKNGLTSAIVNVSHIIPYNKLEADDIKVCENLIFNTELSSAPLYAFIKHFESKNTLDLPKQ---EQDVHLSIEERIQKYLIDGELNAMLELLPSAKDS-ISPEKIINEILIDAMKIVGERFGNGEMQLPFVLQSAEVMKKSVDYLNAFL--PKKQSTHKTTIVLGTVKGDVHDVGKNLVDIILTNNGFSVINIGIKAELEKFLEVLQTQKVDCIGMSGLLVKSTLVMKENLEALKKLDIKIPIMLGGAALNRNFVEEYCKPNYDGVIFYCKDAFDSVAAMQ-IIQSGDFSDLTQKGTKNKEDIEENKITKQEARLKKKLDSPTKCEITFEYATHTPP---FFGVKSLELNANDLDSVFDYIDKDLLFKHRWGYSKLKKEEYQILKAKELEPLLKSLKEEFITKEIFKPVVLYGYFHTRTIEDGLILEVSATKDFIDSEQFLFPRSTKK---PYLCLSDYFNPQ----GDICAMHLVSSGNNFAPYEAELYKNAQYHKYYLAHTLGMDLAEALADFIHAKVR--------------DALQLDAKCGQRYSFGYPACPDLALSVGLFNLFKPESF-GITLSDTYQMSPEATTSALIVPNKEAKYFAI-----------------------------------
ZP_01873173.1 5-methyltetrahydrofolate-- -------------------------------------------------------------------------------MKFLDALKEQILVLDGAMGSMVQLLKLPDSAYGGEEYAMLS-------DLLVFSRPDQVRDIHLEYLKAGANILETNTFGASPLRLQEFDFSALTHYFNIRGIELAQDAIEKYKKEYDGRPLFVAGSIGPSNWVISSTAAN----LNKTDFATIKQNFYLQVKAMMQANVDVLLFETQQDMLELKASIAGAHQAAEELGFKVPIMAQVTVDQFNKMQIFNTDMEAAYAAVGGIGIDVFGINCTLGPELMQKVIPALAQMSELPISVVPNAGQPNGETVYPLAPEKMGEYMRDYEAENGINIVGGCCGTTPAHIAEITKHLGGKKPKVREVKRRNLISGPQNAFELDASEGLIQIGERLNVRGSKKVRDEVEDNIDNDALEEVEQNRDLGIDILDVCMDSNIVNTEKVLPKVIYDMTMDFGGA---FCIDSFAVDALEVAIDVYPGRPIINSIALEEHSPKIDAIVPLTKHHNPVYIALVTDGDGPALTADKKLELAEKIVAESA-KHGVTPDQLMIDINAFPIGAESIEGMNFALESLNSLKPIKAIHPEIMTSIGVGNLTNGLAKKPYMRVVLTSVFLDEGYKRGLDAAIVNPNHFIPVESIEPYDYELGKKVIFDRDMDAFEELETIAESRRGIVKDMPVEEAICEKIKDGYKEKSEGSFEKNEFTYEYKDAIALSMKDHQPLDFINDYLMEAMRELGDGFGRGEVSLPHLLKSADVMKHCMNFLEAYMESLDGKRTFKGTVIIGTVYQDVHSIGKDLAKTLLENYGYRVIDLGVQVPLEKFIDTAIAENADAIGMSALLVQTSNHMITVQQMCQEKGVDFPLLIGGAPVNSRHAAQDDFAAMNGKVFYCQSGMDGVNIMNTLMDSGKRDGLIADNTKKLEQFYRLAIKQAEAREKHESGL---DDRKIDLSDWKAPEGKAIRLADYNVSITDLKQHFDRTLYGLNWDFGGKKAWAKK----GVTEDDLNRMRDEWVQKSDENNWIDPISRFALLPAQSLDNTVAVYNPDDLNEELAQFTFNHVAGRKD---RWSVPQYIHSKKSGEFDLIGIQISSGGAKTEEVINEMREAGELEDCFLLQGLSDRVAEDMADQAHCSARKLA--------------GVDLSQGCRYSPGYPAMEDMANNKIIFDLLKADE-MGISMTDADEFAPTSTTAAFVVFNPDATY--------------------------------------
YP_003038791.1 putative B12-dependent met ---------------------------------------------------------------------YSLRNASSALKALTAISSKRALVLDGAMGTQIQKFKLKPKHYGVEAS-------NGNNDALNMTQPKVVEGVHAAYAAAGSDVLSTNTFCSCSVSQADYGTPYSCSDLNARGCLIARRACLKAGFAQARR-VFVAGVLGPTNKSASIPADASRPSHRDVTFDDLVLSYRQQADALLASGADALLVETVFDTLNAKAGLKACIDASASYRKRRALVASATISDASGRTLSGQTIEAFWVSVKHANLAGVGLNCALGPAQLSRHAAALALAAEAPIWVYPNAGLPNEMGKYTQGAKAFAHALKRCF--GVASAVGGCCGSTPEHISELKALKPKSASRKKLRQPLAVCGTDL---VLAPTTRLCKVSERANVAGSSRFKTLIARKNYSEALEVVRAQACGGAHAIDVNFDDAMLDPKAEMCRFLSLLAAEPDLAKMPVVIDSSSWDVLVAGMKLTQGRSIVNSISLKDGSEPFVSKAQTIKTLGCVPITIAFDELGQATTCERRLEICRRAFKLLTARAGYAPQDVIFDLNTFAVATGIPEHNANAAMLLKAIKLVRCVFPSVTISAGVSNLSFAFRGDARIRRALHSAFLESARGAGLNMAIVNTQEASSGEAATAEASQVCKALILNLRSVTPEEVIGAFASAGVPRRQASSAPTSWRSWS--ARARVAHAVVSGTDKHVADDSVE-LAKSVGALAVVEGALMDGMSVVGKLFEKGKMFLPQVVKSARVMKKAVQALAPMLAPREAAKPH--TVVLATVKGDVHDIGKNIVATVLACNSFRIVDLGIMAASDAIVSAAIAEDAVAIGLSGLISPSLDEMARVARKLQARGVTTPLLVGGATTSKLHTAIRLGPEYGGVVIHVSDASKAVDVLTKLSSSNKAE-FVALVKAEQALTAEVYARAK--ACEACVDHNKAAALSACSSQHPVKAPSFVGLK--------LACWACAGARYRTRSLARTPSNVLE-----AKASKIAERVSKLME---VESWVSVRCRVGVFRATASNNTIALLTAKNKP-VFGVQAPRRQRGSC-----LSLSDFV----SKPSALAGAYCCVVGVEASLIQQFFVKGGKLQAAAAFKTACDALAETCSEQLTRAMRHSVWGFVDASTQSLLK------AGIAPAPGYPVWPDHSAKPKLARAIGAERATALAITSAWSLTPQSSVIAALLAGAPAAYFGVDGVSKQQVAAHAKAAKASVSKTEAALTSALSY---
YP_001560351.1 homocysteine S-methyltrans ------------------------------------------------------------------------------KNEFKAMIEQKIVILDGATGSNLQNAGMPS---------------GVCPETWILDNKEVLITLQKEYLYAGTDILYAPTFTSNRIKLSEYGLEHRIEEINHSLVELSKEAINRYLEETGERSIMIAGDLTMTGEQLL--------PFGKMDFEELITIYKEQIGHLVSSGVDLLVVETMLSLQECRAAVIAAKEICE-----LPVMVSLTFGE-DNRTLYGTDPKTAMIVLQSLGADAVGVNCSSGPKKLSEVIEQMLPVANVPLIAKPNAGLPEDRTVFTMDADEFAASCKIFLELG-VSILGGCCGTTPKHINLLNELAKTYQAPVIHKKPLRVLTTERRSMEFSLVDRFLVVGERINPTGKKVLQAQLREGVLDLVSEMAIEQEELGADILDINMGMNGIDEKEMM---LKVMDEVLQVTNLPLSIDSSHVSVIEAALRRYPGRALINSISLEK--EKFEKLLPVAKKYGAMFILLPLSDAGLPKDLEEKKQII-HTIVSAAKEIGLTAEDIVVDGLVNTVGA----NKEAAIQTMETIRYCKEELS-LATIVGLSNISFGL----PERQFVNATFLSFAIQAGLTMAIANPSQDLLMNTAYAADLLRNKEGADLRYIERVTTHPMINAESTPKKVIERGEDKADDNSTEKSSSQIYEAVIKGNKRKILALVIEEVNNKTSAAEILDTILIPAINQVGQYFDSGKYYLPQLIASAETMKTAIDYLEPMLKKDSK-EEKVGTIIIATVAGDIHDIGKNLVALMLKNYGFNVIDLGKDVSSEKIIETAKELDADIIALSALMTTTMLEMKRVVNYRNEASLRAKVIIGGAVITQDY------CDEIGADGYSKDAQEAVNLVKKLLK-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
YP_076329.1 5-methyltetrahydrofolate S -------------------------------------------------------------------------------MKLEDMLGREVLVFDGAMGTMLQAQGL---------------APGACPDVWNLERPEDVIAVHRAYVEAGAQILETNTFGSTPIRLGHYGLQDRCRDIVVAGVRCAREAAA--------GRAWVAGSMGPLGALVE--------PLGELPFDEAYAQFAVQARAFAEAQPDFIIIETIADLNELRAAVLACRDHAP----GIRIIAQITL-DPSGRAFTGTDPETAALVLQSLGADVIGFNCSVGPDLLVEAVARMARVARVPISVQPNAGLPDGATRFPMGPEEFAAYGPKLVEAG-AALVGGCCGTTPEHIRRLRAAVEKPPARPGPLAHTLGLASRTRSLFFVEQNLPVVIGERINPTGRKLLTRDIREGAFQRVRAEAKQQVEAGAAVLDVNVGVPLIDEPAAMARAVRVIQ---DAVDVPLCLDSPDPAALEAGLKACVGKPLLNSFSLEEG--RAEAVLPLARRYGAAVLGLTIDEKGIPASAEQRLAIARRLV-AAAEAHGIPRHDVVIDPLALTAGAQQAE----AKETLKAIRWITDEL-GVLASLGVSNISFGL----PNRHFLNAVYLSMAVTEGLAMAIMNPLDERMMDTVRALRLFLNRDMQAVGPKRLVHTVEEALKAAAKAGEIAPAAVTPSSGAADELGRRLHDAILEGDREAIVPLVEQGLAEGRDPMDMLNRHLIPAIEEVGRLFGEGIYFLPQLMLSAQAMKKAFARLKPEIQKAKVGQTEIGTVVLATVQGDIHDIGKNIVAVLLENYGFRVVDLGRDVKNEVVLEEARKVGADMVGLSALMTTTMPQMKRVIELFAREGFDCPVIVGGAATTKAFAE------QIGARGHGRDAQEAVALALEVLKERRAGR-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
ZP_02930588.1 Methionine synthase [Verru ---------------------------------------------------------------------------PNARPELEALLRKRILVIDGAMGTTIRGYGLSEEDTRGKRFADAPKDLKNNGDILSLTRPDVIGDIHRRFLVAGADIIETNTFSGSSIAQSEFFKEDLAWDINYESAQLCRKWADNIGSDT-GRKRYVAGAIGPLTVSLSVSPDADDAGFRVVTFDQVVEDYRRQARALIAGGCDILLVETIFDSLNAKAAIVALQEVFKEDGLELPLMVSAAVGLGGETMISAQKAEALWNAVRSANPLAIGLNCSLGPDKMRPFLSELSAKADAFVSAYPNAGMPNTPTGFDLEPKHMGEYITDFAGAGLVNFVGGCCGNTPDHIAAIAKAAEQFAPREIPVIEPLLRLSGTEPFTRERDSNYLMIGERTNVAGSPKFAKLIKENKLEEAVGIARQQVENGANVIDICMDEGLIDGVVMMDKFLRLVTAEPEIAKVPFMVDSSKWEVIEAGLKCLQGKGIVNSISLKEGEELFKERARTIKRYGAATVVMAFDENGQAATYEEKIRICERAYRILVDEVDFNPEDIIFDPNILTVATGMEEHNNYAVDFIEATRWIKQNLPGAKVSGGVSNISFSFRGNNKVREAMHSAFLYHAIKAGMDMGIVNAGMLEVYEDIPQEMLVKVEDVLLNRRPDATEILVDYAEQFKGQTG-AKKQEVDLAWREQSVGKRLEHALLRGITDFIDQDTQEALDELKVPLKVIEGPLMDGMSVVGDLFGAGKMFLPQVVKSARVMKKSVAYLEPFMEAEKEARARLVVV----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
YP_388607.1 methionine synthase (B12-d ----------------------------------------------------------------------------AAVPDFRRALSDDTLLFDGAMGTMLQGRGLP---------------AGMSPEVFCLSNPAVLQGVHLDYARAGADVLTTNTFGGTRLKLPEGMN---VVEFNRE-----MARAAKAAAGQAGRTVFVAGSVGPTGHFV--------KPLGDLEFSELVDIFREQIRGLVQGGIDLVLAETHFDLAEVRAVVLAARAEC-----NLPVGVSMTF--EDGVSLTGTRPEVFVHTMQNMGVDLIATNCSAGPEQMAGVVAGLTAAGDIPVLVMPNAGLPNGNTVFRLGPEEFAAQTADFVRAG-VRCLGGCCGTTPDHIAALAREARSKPRPAVEKRRRSGIVLTTRCLRIGHDQPCRIIGERINPTGKKELTAQLQAGDFTLAMQFAQQQIDAGAPLLDVNVGAPMVDEKVLLPQL---ISDLAAAHGVPLSIDSSDMDAVEASLAVYAGSPLVNSISGEPG--RMERLGPLCRDYGAPFVLLPLKGRKLPVTAAERISIIDELLLQ-ADDLGIPRRLVMVDVLALAVS-SKAEAARHCFDTIRYCNE----ELGLPTTIGLSNISFGL----PARELLNATFLAMAVGAGLTSCIAHPGNVRLREALAAAEVLMARDSNAERFIAGYSGWTSGGGSGGIIAGGGEEKKRPVS---------LEEAVIRGERDIILELVEDELARGAQPYALVNERLIPAITEVGDKYERKEYYLPQLLRSAETMQKAFGRLKPLLEEAS-GGETKPVIIMATVEGDIHDIGKNIVCLMLGNHGFDVVDLGKDVKAVDIVDAAVEHNAKLIGLSALMTTTMVRMEDTIQLLRERGLSIPVFVGGAVVTPAFAE------AIGAAGYSRDAVEAVRIARGLVEAPAR---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
ZP_01771753.1 Hypothetical protein COLAE ------------------------------------------------------APVDAVRRNGATYKTRTIDDLRIKDDRLRAAIETGHLLFDGGMGTMLQAAGM---------------KAGALPELLNFEEPQVITDIQRQYVEAGCDVITANTFGANAHKLD-------------GAATVADVFAAAVTCARAAGAHYVAGDIGPIGALL--------RPLGTLSFDEAYDLFAEEVRAGVAAGVDLFIIETMTDLAEIKAAVLACRE-----NSDLPVFATMTF-EEDGRTFLGTSPEVAAITLDAIGADVLGINCSQGPAELRGLAARMLTVTDKPVMVQANAGLPDGNTVFDIQAPEYAEAVAGMIADG-VSVVGGCCGTTPAHMAALRTLIDNHTPSPRHRKPSMSVTSAQTVVDLPCDGHKIVIGERINPTGKKRLQQALRDGDLDYVVSQGISQQEQGADILDVNVGLPEIDEVKIIQQAT---EQLQGSTLLPLQIDSTDPAAVEAAVRRYAGKPIINSVNGKQ--QIMDEIFPLVAHYGTNVVGLTLDEGGIPDTAEARFAIAEHIVAEAA-RYGIGPDRILIDCLVMTAST----NQRQAEQILRAMSLCKERL-GVKCALGVSNISFGL----PARPLLGSVFLAAAFGAGLDAPIMNPGSKRFMDTVYSYRVLSVEDEYIERYAGWTDPYKIAANPAAAQAASTDTVPAAGTAGTDDPIRRMVVSGRKGEIAAET----ERLLADHDAMDLINNHFIPALDEVGVLFDQGKFFLPQLMASAEAARVGFDTIKRLMPAGEIAD--KGKICVATVKGDIHDIGKNIVKMLLDNYGYTVFDLGRDVDPQEVLKTVKERDIKLVGLSALMTTTVVAMEETIKLLHAEVPGVKIIVGGAVLT------PEYAKQIGADYYAKDAAESARIAEEVFGQ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
B4DST3 cDNA FLJ56487, highly simi -----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------AGLKCCQGKCIVNSISLKEGEDDFLEKARKIKKY------GAAMVVMAFDEEGQTQGTGGKKVIQTDEWRNGPVEERLEYALVKGIEKHIIEDTEEARKKYPRPLNIIEGPLMNGMKIVGDLFGAGKMFLPQVIKSARVMKKAVGHLIPFMEKEEEEDPYQGTIVLATVKGDVHDIGKNIVGVVLGCNNFRVIDLGVMTPCDKILKAALDHKADIIGLSGLITPSLDEMIFVAKEMERLAIRIPLLIGGATTSKTHTAVKIAPRYSAPVIHVLDASKSVVVCSQLLDENLKDEYFEEIMEEYEDIRQDHYESLKERRYLPLSQARKSGFQMDWLSEPHPVPTFIGTQVFEYDLQKLVDYIDWKPFFDVWQLRGKYPNIFNDKTVGGEARKVYDDAHNMLNTLISQKKLRARGVVGFWPAQSIQDDIHLYAEAAVPQPIATFYGLRQQAEKDTEPYYCLSDFIAPLHSGIRDYLGLFAV-ACFGVEELSKAYEDDGDDYSSIMVKALGDRLAEAFAEELHERVRRELWAYCGSEQLDVADLRRLRYKGIRPAPGYPSQPDHTEKLTMWRLADIEQSTGIRLTESLAMAPASAVSGLYFSNLKSKYFAVGKISKDQVEDYALRKNISVAEVEKCMS--------
YP_001916863.1 homocysteine S-methyltrans ---------------------------------------------------------------------------MKLKDQLVNKTLEKLLFLDGSYGTELQRRGFE-----------------GNAEILNLQDQDLVKNVHYDYASAGADLILTNTFGGNRLKLKDAGYEDKVAEINSRGVELAKESAE-----NIDRDVLVVGDISSTGRFIE--------PVGDLSFTKAQQVFQEQGRYLIESGVDLIKIETMTDIKELKAAILGIRSIDE----DLPLIVSMSF-EQDGKTITGTSVPSYVTLMNDLPVDIIGLNCGVKSKDMLDLVKQASYYSLKPLSISPNAGDPDLDLSYSEDPQEFSFYLDAISDLDMVAIVGGCCGTTPEYVDNYCSKLKGKEKQQSQIHKDIPTLISSRTYQLDLDNNFVKIGERINPASKKNFQEEINNKDFSRIYDEAFSQMNEGSDVIDLNLGVEEDVELEDVETIVNGLDSL---GCKPLSLDIQSSVLLEKALQVYPGRPIINSSSCDKED--LDNAIDLMKKYGGVLVLLAMSGTPK-KTIQKRLDELKYGLEYL-ESKGIDESRIMVDPLVLPVGT--EHDPKTTLELIKII----SQEMECKTTLGLSNLSHGL----PDRPQLNSAFVSMAIYNGLDSAIMDTSDQLVTQTVEKSLMLMGKETIW-------------------------------EDVAIDTEDQMVKDILTGNSDKVLTQVKSYL-KDMTPLEVSQQLLGKAMKEIGDLYNDKSIYLPQLLLSAETVQPSFDYLNKLV--GEHQEDSKGKIMLATVEGDVHDIGKKIVGTILKSGGFEIYDLGVDLPANEIVAEVKDIKPDILGLSAMMTSTIKKIAEVTEQLQAEGIDVKVIGGGASLN------PELAQKFGCHAYAKDAHEALTKCEQLMTGEKA---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
B9KC48 5-methyltetrahydrofolate S ------------------------------------------------------------------------------RREVAKMLSEKVLLLDGAYGTEFMKLGHEEL-----------------PEELNIKAPEVVFKVHRTYIESGSDAVLTNTFGATKMKLRKHGLENELDSIVRNAVRIARKAAGE---------RLVFGDIGPTGELP--------FPLGNTLFEEFYENFKETARIMVEEGVDGIILETFSDILELKAAVLAVRDVSKDVF----LIAHMTF-DENGRSLTGTDPVNFALTFDELDVDALGINCSLGPEEILPIFQELSQYTDKFLVVEPNAGKPNGKTVYPLKPEDFAVHIDSYYEAG-VNIFGGCCGTTPEHIKLFRKVLG---SRKPLPRKKKKIIAVSSPSKLVTFDHFVVIGERINPAGRKKLWKKMQEGNLDVVANEAKDQVEKGAEVLDVNFG---IESQVDPSYVEKVVQSLPYTASVPLSLDVQSLNLAERSLRVYPGRPLFNSSKVTEKD--LEEKINMLKKYGGVLIVLLMEND-VPKTFEERKKNFEKALKILEEHRFL--DRVLFDPGVLPL--GAEGKPTEVLKTIEYISKM-----DFKTTVGLSNLSFGL----PDRSFYNTAFLVLGISKGLSSAIMNPLDENLMKTLDSTLVIL-----------------------------EKKDLPKAEVREDKLVEAILSGRREDVEKEVENL-----LKEKDPLSIIEEHLRPAMEKIGLLYDKGKIFLPQLILAAQTVKPVFDKLASMLSSEN----QGETFVIATVKGDVHDIGKNIVASVIRSSGYRVVDLGKDVDTERIVEAVEKEKPVALGLSAMMTTTVGRIKEVVESLKKKGLKVPVIAGGASLNEK------LAKELGADYYAKNASEAVKILKSL---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
YP_001681058.1 methionine synthase, putat -----------------------------------------------------------------------------------------IKLFDGAMGTMLQAAGL---------------LPGACPERFNLEHPERVTAIHRRYVEMGAEIIETNTFGATRLKLAHYRMADQVEAVCHAAVRAARAAC--------GPATKIAGSVGPTGKLIA--------PLGELSFEEAVDVYSEQISALAAVGVDYILIETIIDIQEMRAALLAAKAVAK-----VPVICQLSFG-ADGRTVTGTDPATAAYLLEAMGADVIGVNCSLGPAQLLPVIEAIAGATNLPISAQPNAGMPDGRTVFPMSPEEFASWAPKLAAAGA-TYLGGCCGTTPEHIAAAKAALEAAYPGGAAPAPVTALTSRSRTVFLGPAFSPVIIGERINPTGRKALAAEIKGGSWLTVKRDAIEQVRAGAQILDVNMGVPGINQAKAMET---AITELSLLVDVPLAIDTTDAAALEAGLRVYPGRALINSVSAEP--DRLREFLPLAKKYGAAVLCLPIAPGGVPQTAQERVAIAQQIVDAALA-AGLRRQDLLLDPLVMTVAT----DANAARETLETLRSYRKTF-GFPTVMGLSNVSFGL----PRRNLVNAAFCALALDAGLDAPIMNPFDETLSDCWNAAQVLLG------HDKQGQRFCIRYAQSAGAPSS---AKVAGNAATEGDVLTCIRKAVIAGEKESVIPLVRKALAEGLTAIAITEGGLTTAMTEIGEAYGSGRCFLPQVMLAAETMRVAFQTLKAELPSQDM--ASKGRVLLATVRGDIHDLGKNIVAALLENNGFTVIDLGKDVPAERIVAEARAQRADVVGLCALMTTTLPEIDHTIAALKAAGVECLTMAGGAVVTAEYAAAA------GVDGYAPDAVSAVKLTEELLKRRKRGKTRGLT--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
YP_860387.1 5-methyltetrahydrofolate-- -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LSALKKAPPSGAGGAGKVLMATVKGDVHDIGKNIVAVVLGCNNYEIIDLGVMVPPEKIIETAKAENVDVIGLSGLITPSLDEMVFLAKEMQRQNFEVPLLIGGATTSKAHTAVKIDPQYHFAVAHVNDASRAVTVVGQLLKESTREKYKSDLKIEYDKFRLNFKKRSKVKSYLKLPEARRNKFKINWESTNITKPNQLGTQIIEFDLEKLEEYIDWSPFFRSWDLHGRYPDILKDEKVGEQAQSLFDDAKALLERIFKEKLLKAKATFGLFEANTINDDIEVSYEEASEKKKIVFRTLRQQLKKYAEPNFALSDFIAPKESGIQDYMGCFCVTTGFGTAELAAEFEKDLDDYNSIMIKALADRLAEAFAEYLHKEVRTKHWGYASDENLSNEELIKESYKGIRPAPGYPACPDHLEKLTIWELLKVDEKIGVELTESLAMWPAASVSGYYFANPEARYFGLGKIKEDQVKDFAERKGIEYKKAEKWLNPNIA----
B4DST3 cDNA FLJ56487, highly simi --------------------------------------------------------------------------KKTLRDEINAILQKRIMVLDGGMGTMIQREKLNEEHFRGQEFKDHARPLKGNNDILSITQPDVIYQIHKEYLLAGADIIETNTFSSTSIAQADYGLEHLAYRMNMCSAGVARKAAEEVTLQT-GIKRFVAGALGPTNKTLSVSPSVERPDYRNITFDELVEAYQEQAKGLLDGGVDILLIETIFDTANAKAALFALQNLFEEKYAPRPIFISGTIVDKSGRTLSGQTGEGFVISVSHGEPLCIGLNCALGAAEMRPFIEIIGKCTTAYVLCYPNAGLPNTFGDYDETPSMMAKHLKDFAMDGLVNIVGGCCGSTPDHIREIAEAVKNCKPRVPPAFEGHMLLSGLEPFRIGPYTNFVNIGERCNVAGSRKFAKLIMAGNYEEALCVAKVQVEMGAQVLDVNMDDGMLDGPSAMTRFCNLIASEPDIAKVPLCIDSSNFAVIEAGLKCCQGKCIVNSISLKEGEDDFLEKARKIKKYGAAMVVMAFDEEGQTQ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
ZP_02930588.1 Methionine synthase [Verru ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------TDLLPAELAQSGAGVIVLATVKGDVHDIGKNIVGVVMACNGFRVIDLGVMVSCDKILEVAKAEKANVIGLSGLITPSLDEMVHVAKEMERNGFTVPLLIGGATTSAAHTAIKIAPHYKEPIVHVLDASRSVPVMTSLLSEEQKAGFKVQNEERHAKLREQYAQRDDASKLLPLAEAQAKGSQFDWSTQEIAVPEFTGVRVFPLPISEVVPFIDWSPFFHTWELRGRWNEPEFQDQVEPEAAKLYKDARAILDQVIAENLYTIRACFGFFPANRIGDDIEVYTDETRTEVRCVFHTLRQQMPKKDKPNYALADFVAPKDSGRADYIGGFCVGI-HGADEWAEKFKIALDDYNGIMAKAIADRLAEATAEYMHKQAR-LAWGYEKPEELSNDDLIRERYRGIRPAPGYPAQPDHTEKPILFDLLNATERTGVFLTESNAMHPGAAVSGLYFGHPDARYFAVGKINKDQIEDYAARKGETVEHMEKWLGPWLAY---
XP_001702462.1 cobalamin-dependent methio ---------------------------KIASAPAGP--KITPRLNPIPAGKDQLAPDAKPAPVPKYKAWKDGVKPTAAFVPLDKLMRERIIFIDGAMGTQIQKFTLEEEDFRGERYAKHSHELKGNNDLLVITRPDVIGKIHTAYLEAGADIIETNTFNGTWISQSDYELDEEVALINRTAAQLAKKCVADFLAKNPGSPRFVAGAIGPTNKTLSVSPSVENPAFRGITYDEVVDAYYKQAEALVEGGVDMFLVETIFDTLNAKAAMYALEKFFSDKGMRLPVFVSGTIVDNSGRTLSGQTNEAFWNSIRHAKPMAVGLNCALGAKDMLKYVANLAACADCYVFCYPNAGLPNAMGGYDQKGDEMAEEIRPFCEGNLVNAIGGCCGTGPEHIAAIKKMASAYKPRKPVTVPPLMRLSGLEPLNYTPDRTFLNIGERCNVAGSILFKKAIVNNDFDTAVAIALKQVQQGADVLDINMDDGLI----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
C0FPZ7 Putative uncharacterized p ------------------------------------------------------------------------------KAEFKKLVENGPVILDGATGTNLQKAGMP---------------VGVCPEQWILENPDIMIKLQEDYVAAGTDILYAPTFTANRIKLEEYGLADRLEEMNRE--------LIALSQKAAQGKALVAADMTMTGQQL--------YPIGDLMFEDLVDVYKEQAEVVADAGADLFVVETMMSLQECRAAVIAIREVC-----DLPIMVSLT-YNPDGRTLYGTDPATATVVLQSLGADAIGINCSTGPEDMIEPVEKMAEYATIPILAKPNAGLPNGVTVYKTGPEEFASCGKKLVEAG-ASIIGGCCGTTPEHIRALKEAVKDMPVHKPLTQKRRILTSERKLVEITLDGNFMVIGERINPTGKKKLQAELREGSLNMVRQMALDQEENGAAILDVNMGMNGIDEKEMM---INTIYEVTSTVDCPLCIDSSHVDIIEAALRIYPGRALINSISMEK--EKMDKLLPIAEKYGAMFILLPLSDAGLPNDSEEKHAIIRTVMEQAI-KIGMSKEDIIVDGLVATIGA----NPRAAIECYETFSYCKNEL-GLPTACGLSNISFGL----PERTYVNTAFLTMAIAHGLTMAIANPSQELLMNAAFASDLLLAREESDIRYIERMNMLAEKYAGQERVLVPVKKRRRMIRQNLDHRKEEVL-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Q8BUC4 Putative uncharacterized p -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ERKYVPLSQARKHGFHIDWLSEPHPVPTFIGTQVFEYNLQKLVDYIDWKPFFDVWQLRGKYPNIFNDKAVGEEARKVYNDAQNMLNILISQKKLQARGVVGFWPAQSVQDDIHLYAEGVVPQPIATFYGLRQQAEKDTDPYHCLSDFIAPLHSGVCDYLGLFAV-ACFGVEELSKTYEDDGDDYSSIMVKALGDRLAEAFAEELHERVRRELWAYSRSEQLGVPDLRRLRYEGIRPAPGYPSQPDHTEKLTMWRLASIEQATGIRLTESLAMAPASAVSGLYFSNVKAKYFAVGKISKDQTEDYALRKNMPVAEVEKWLGPILGYDTD
ZP_01788142.1 MetH protein [Haemophilus --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------DIIALSGFSGEWADYVPPTPKQTGIVEFNVPIAELRKFIDWSPFFRIWGLMGGYPDAFDYPEGGKEARKVWNDAQVVLDELEQNHKLNPSGILGIFPAERVDDDVVLFSDEERTKTIGTAYGLRQQTERGKNSNFCLSDFIADRESGKKDWFGMFAVCAGVEEMDLVEGYKAAGDDYNAILLQAVGDRLAEAMAEYLHFELRTRIWGYTQ-EEFDNQGLINENYVGIRPAPGYPSCPEHTEKALIWDLLEVEQCIGMKLTESYAMWPAASVCGWYFTHPVSNYFTLGRIDEDQAQGYAKRKGWDERDDE------------
Q4SYB4 Chromosome undetermined SC ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------VPLCIDSSNFSVIEAGLKCCQGKCIVNSISLKEGESDFLDKAASVKRYGAAVVVMAFDEHGQVLNTDRKVEICTRAYQLLLTKVGFKPNDIIFDPNILTIGTGIEEHSEYAINFIKATKLIKETLPGARVSGGLSNLSFSFRGMEVIREAMHGVFLYHAIKQGSSWKIWILRNLKLVTD-SSHTFDVEEPVYVGLPAKVRHGFLGLC---RATTVVRRTHPRPRWGLSWWCRCLSMYSSAVGVDKYVVEDVKKCVDRYTRPIHIIEGPLMSGMKIV--------------IKSARVMKKAVGYLIPFMEKEREDDPYMGTIVLATVKGDVHDIGKNIVGVVLSCNNFRVIDLGVMVPCDKILKEAIIHNADIIGLSGLITPSLDEMIHVAKEMERLRMTIPLLIGGATTSKTHTAVKIAPRYAAPVIHVLDASRSVVVCSQLLDEMGKEDYFEDVKQDYEEVRQEHYDSLKAFAEELHARVRKEFWAYSTTETLQTSDLHQVRYQGIRPAPGYPSQPDHTEKTTMWSLAG-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
YP_590922.1 methionine synthase (B12-d ------------------------------------------------KSGCSMQRVHAHPPDTAHRKRLTAASNKQMKRPIERILEDRIAIIDGAMGTTIRTYGMAEADIRGERFKDSSKGLLNNGDLFSLTQPQMIGDIHRRFLEAGADIIETNTFGATSIVQSEFFVDDLAWEINETSAQQCREWADRVANATS-RPRFVAGALGPLTVSLSNSPDADDPGFRVVTFDQVKIAYIQQVRALIAGGVDFLLVETIFDSLNAKAALVAIREVFDQDGKNIPVMISAAVGRGGETMISGQTVEAFWNAVSHVKPLSVGLNCSLGPDLMYPFLEDLSAKADVAISCYPNAGLPNAATGFDFGPPDMARYLREFAEAGLINIAGGCCGNTPEHIAAIAKALEGLPPRKIQP----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
YP_002506189.1 homocysteine S-methyltrans -------------------------------------------------------------------------------MSFLNDIEKKVLVFDGSMGIMLQSKGL---------------EVGTCPEEWNITHPEMVKEIYTAYRDAGANVIQSNTFQSNLMKLSEYGLQDKHYDINFAGVSLAKEV--------MGDKGYVAASIGPLGKLLE--------PFGELTFEQAYNTFKEQVVAVTAGGADIISFETFTDVSEMRIALLASKE-----NCNLPVICSIS-YEQNGRTLMGSDPAVCACILHSLGADMIGTNCSFGPEYMIKVAESYGK-TGLKFSIKPNAGIPDGNLVYDETPEKFAEYAQEFIKYG-ARLVGGCCGTRPEFIAEISKAVSGC---DAVSFPLNVDFITSSSKAVAFSDIMGAGIGWIDINKEETLKKELLAGSISTITDAAMDLMEEDCELIAIDVD---VPGENEL-LLSYVVKEAQTYLKQPFILKSNNPSALEAALRIYKGK-------AGVLTNNSSDVAGIMNKYGAVNVGGFISNE-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
XP_001702462.1 cobalamin-dependent methio ----------------------VVRLGGASSGP-----KITPRLNPIPAGKDQLAPDAKPAPVPKYKAWKDGVKPTAAFVPLDKLMRERIIFIDGAMGTQIQKFTLEEEDFRGERYAKHSHEIPGNNDLLVITRPDVISKIHTAYLEAGADIIETNTFNGTWISQSDYELDEEVALINRTAAQLAKKCVADFLAKNPGSPRFVAGAIGPTNKTLSVSPSVENPAFRGITYDEVVDAYYKQAEALVEGGVDMFLVETIFDTLNAKAAMYALEKFFSDKGMRLPVFVSGTIVDNSGRTLSGQTNEAFWNSIRHAKPMAVGLNCALGAKDMLNIL---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
C0UX63 Methylenetetrahydrofolate -----------------------------------------------------------------------------MKDPFVERLEKGPILSDGAIGTQLYERGVPYGKSF---------------DELNIVDPSLVSGVHIDYLRAGAEIITTNTFGANRIRLKEFGLEKKVRDINLRGVKIAREARE-----IVGVPAFIAGSVGPIGRPATEYNSLTDRVIGDT--------FREQIEALLEGGADVIMFETFSELEELLIAIEVAKEVCE-----LPIIAQMSFGE-DELTHGGDTPEDFVRALKDSDVDVIGVNCSVGPQGTLDVVMRLIAAGAHRVSAQPNAGLPSRRGVYISTPEYFAEYAKKFVSAGAV-IVGGCCGTTPAHISAMAAAIKDGNRATTVTVNIEQKSPHITAIPSGEPEPTIKRGEFI----VSVEVDPPKGLSARKTLEGAKMLAEKGVKWINIG-DSPMARVRMSCIALAKLIQE-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
YP_860387.1 5-methyltetrahydrofolate-- --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------KTNQSPSGRPGGARPLKLSGLEPLVITPESNFINVGERTNVAGSKKFLRLIKEEKFDEALAVAREQVDNGAQIIDINMDDGLIEGKEAMVKFLNLVVAEPDIARVPIMIDSSKWEIIEAGLQVVQGKCVVNSISLKEGEEEFITHAKKIKRYGAAVIVMAFDEVGQADNYERRIEIAKRSYDILVNKVNFPPEDIIFDLNIFPVGTGMDEHRRNAIDFIEGTRWVKENLAHCSVSGGVSNVSFSFRGNNPVREAMHSVFLYHAIKAGMNIGIVNPSMLEVYDEIPKDLLEHVEDVIFDRRDDATERLLNFAENVVGRKKE---NKVDLSWREKPLQDRITHALVKGIDAYILEDIEQARLEAERPLDVIEGPLMIGMNVVGDLFGSGKMFLPQVVKSARVMKKAVAYLLPYIEEAKKAPQPPK------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
ZP_02081447.1 hypothetical protein CLOLE -----------------------------------------------------------------------------------------PLILDGATGTNLIAAGMPS---------------GVCVEQWILEHPEKLLALQRAFLEAGSNAVMAPTFGANREKLAAYGLQDQVEEINLKLVALSKEAAEPF-------HALVGGDVSPAGVMIE--------PYGDLTFDELYDIYLEQIRALKKAGVDFIALETQMSLADLRAGVLAAKEA------GLPVFATITVED-NGRTIMGTKFLPVLITLQALGAAAVGLNCSTGPEVMEELLEGAVSHAQVPLIAKPNAGKPEDPAVYPLSPAEFAEKMESLLAAG-AQIVGGCCGSTPEHIRELAQTVENTYRELAPQEPDHAAAIESESFFLGDDISLSEPLECSYDLGD-------------DLIDIEDEQVN--AALVEVNSIDD-----------AKLLIENASMTRLPIVVRIHNLDVLEYTLRNFQGRLIVDSAC----DLEEEEMRPIVDYYGA-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
C1F3L2 Methylenetetrahydrofolate -----------------------------------------------------------------------------MNNRLKEIFGDRPVLCDGAMGTSLYARGIFINR---------------CFDELNLSQPELVRSVHEDYLQAGAEIIETNTFGANAIRLRRYGLQDKVAEINQAGARIARAAVAQLADKQAGN-AWVAGSVGPLGVRLE--------PLGKVGLDEAQAIFAEQIEGLVAGGVDLLVIETMPALNEAQQAIRAARAVAPE----LPVIAMVTV-DEESRCLDGTAPEVAAARLAGWGADAVGVNCSTGPAAVLTAIECMAEATDLPLAAMPNAGMPDGRNIYLCSPEYMASFARKFHKSG-VQFLGGCCGTTPNHIRAMKSFLRASEAQKAAVQHSRSAPIVTETPPAPIEQRSRMIHDRTFVTMVEIV--PPRGIDCQKEIDGATMLAGLGVHVINV-PDSPRASARMSAQSLCIQLQQKSGIETLVLSIQSDLLGASSIGLRNI-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
ZP_01288844.1 Methylenetetrahydrofolate ----------------------------ARAAPQRLCCGAERFCSRQMVSGCFTTRGWLLPPPGNRAHQHDNRDRQPMKPDFLEYLQEKVILGDGAIGTYLYSKGI---------------ELGKDTDRLNLSDPDLIYSLHEEYIRAGSQLIETNTFGANRLKLLANGLENQAREINLAGAGIAKRAA--------GEDIYVAGSVGPTGVEFPL-------EAGEIEPAEVAAAYEEQISALLEAEVDLLILETFTHLDELLIALETARRLAPQH----PIVAQMA-YPAQGRTARGDHALTCGTAAIAAGASLVGANCGRGVNSMLTAIEALSPLRDVPLSAFPNAGFPEIVGIYPAQPEYMARVVGEMIKLG-ARLVGGCCGTSPTHIQEFRKQLKIAKRPVAHARAASMEAQASDQPQTANKVGSLLRELQPDRMPILVELDPPTHLDMGGVLEGAKALAAGGTDAISLG-ESPLAVLRTENLALAHRIQQEAGIKTI------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
ZP_02330511.1 bifunctional homocysteine -------------------------------------------------------------------------GEKEMRPDLRLALQHQLLTGDGAMGTYLYQLGFP---------------VGISYEELNLLQPQVIADIHRRYYEAGAKIIETNTFSANKEKLSKFGLEQEVKRINRAGADLARQ--------TVGDDAYVMGAVGSI----------RGSKRKNVLEADVRIAFHEQVEALLEASVDGLLLETFYDLDELLIALRLIRNL-----SDLPVICQFT-TEGNHTTHDGIPLQEAFERLKDEGADVVGFNCVSGPNGIMQSIGRIHPLEQVPFSVYPNAGIPDGRIVFGATPEYFAETALRFADLG-ARIIGGCCGTTPEHIAAISKALRGYVPSAEQAFRLRGTETGRDEEHPVISTGTAE-------TGDSSYMDGVQN----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
ZP_02435545.1 hypothetical protein BACST -----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------RQQEHNIVLSIQSITLYRDYQLPTINYKIHEVSPYINWIYFFHAWGFQPKFAAPQEERSKAAEAMQLFKEAGRVLNRLDE--KISVQCIYRLCSANAEGDNLIIED--------TVFPLLRQQTPHPGSPFLCLSDFIRPLSSGVPDTIGLFASSVSAESEGC-----YKDDPYKHLLVQTLTDRLAEAATEKMHEYVRKTVWGYAPDESLSIPDLLVEKYQGIRPAVGYPSLPDQSVNFILDELLDMKQ-IGITLTENGAMYPHASVCGLMFSHPQSRYFAVGKIGEDQLEDYACRRGKPIEEMRKFLAANL-----
XP_002116182.1 hypothetical protein TRIAD -------------------------------------------------------------------------------------MDKEILVIDGACGTELQRLGYDVD-----ADPLWSAS-------LLLTNPQVIKDLHTSYLNAGADIILTATYQASIPGLVQYATEASASAVIAMAVRLAIEARDEFWAEQRRPKPLVVGSVGPFGACQHDGSEFHGRYTDEMTIEELKQWHKPRIMELIQNGVDLIAFETIPAEKEAIALIQVL-----ETFRGVKAWLSFVCKDDLHLNHGELFADVMERFRNHNQIVAIGTNCT-NPQNVDNLIQSCKRLDDKPFIAYPNSGESWSVDRWDPTPVELSDYVQRWIKNG-IRWIGGCCRTTPSDILKIRNKVDGIPK---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
B6TK96 Homocysteine S-methyltrans ------------------------------------------------------------------------------------------LVLDGGLATELEANGADLND------PLWSAKC-------LLSSPHLIRKVHMDYLEAGANIIITASYQATIQGFESKGFSEQSENLLTKSVQIALEAREMFLKEHLEKPILVAAALGSYGAYLADGSEYSGDYGEAGTKEFLKDFHRRRLQVLAEAGPDLIAFETIPNKLEAQAYVELLEE----CNINIPSWLSFNSKDGVHVVSGDSLIECATIADKCAKVGAVGINCT-PPRFIHGLILSIRKVTDKPILIYPNSGERYDGEKKEWSDGDFVSYVNEWCKDG-AALIGGCCRTTPNTIRAIHRTLNQ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
ZP_02444417.1 hypothetical protein ANACO -----------------------------------------------------------------------------------------PLLLDGATGTEYMKAGLPS---------------GVCVEQWAAEHPDVVARVARGYADAGSDIVYAPTFLANAGNLKNYGLSEQVIPLNRKIVSTVKQALA-------GRDVLVAGDMSTTGLMCE--------PFGETEFVHLIGIYAEQASALADAGAELLVIETMSALSECRAAVIAARQ------TGLPVFLTMTV-DAEGRTMWGDDVLASMIVLQDMGISAFGLNCSQGPDDMVPLFERIAPYAKLPLIAKPNAGEP------PLSPVQFCDKCARLMRRG-VKIIGGCCGTTPEYVSALRHMIDSFDIGRVNIAPAGYDILAAGRNVYYLDN-------------DLEYSKPIACE-----IDMADALLEASHESCDAVLIH--LDTPDDGYRF----SLNAHMVDMPVAFESESLEALDAALLHYNGKALVVSTSCELEREVL---EEVAARYGAVVL--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
YP_002572237.1 homocysteine S-methyltrans ---------------------------------------------------------------------------------LQDELYRRVLIFDGAMGTQLIQNGLTEDE---------------CPDLWSVTRQDVVSSIHRQYFEAGSDCVETNTFGANREKLKKYGLENEVENINKCAVKLAKEVAKEYSG-------YVGLSVGPTGRLFIPS--------GDLSFDEAESIFYEQILSGIEAGADFVSIETMSDIKEAKAAFFAYKKAKEELKKDIPCLISLTF-EQNKRLLMGTPPEVAAYYFSSIGCDIVGANCSGGAIQLLEIIKQMQFFSFVPLSVKPNAGLPDGKTIYESCIPEFVNLADEFVENG-VRLYGGCCGTNPEYIKSISKVLKG---------KEVSFESSTQKKFITS------IYSLLDISQKFSVYEFKLTNDFSPEAVFELAGLEEDVIFVDI-------DENVEPEVLKEFLIESQDFSKKPFNIETSHVDVIERAVSSIHGKSAVN----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
C4V3M8 Homocysteine S-methyltrans ----------------------------------------------------------------PRAGGHFLAWRDGMNVLEVRLAAQDVLVLDGALATELEARGFSVDD------PLWSAKA-------LFERPDLVRDIHLDYLRAGADVLTSASYQATVDGFMQRGFAEEAAELLRRSVRLAQEARGLYRAERSTGTPLVAASVGPYGAYLADGSEYRGDY--DVEEDALTAFHAQRLRILASAAPDLLACETLPCLHEACAIVRSLR----AEGIRIPAYFSFSCRDGAH-ISDGTEIAECARVLDAPEAAAIGVNCTA-PQYVSGLIRMIRQETDKPIVVYPNSGEYYDAAARVWAAEDFGARSREYAAAG-ARIIGGCCRTTPHDTAAIAAWVKAGRKR--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Q4S116 Chromosome 1 SCAF14770, wh -------------------------------------------------------------------------------PRLNRYLCDDPFILDGGLATDLEAQGVHL-----QGDPLWSA-------RLLYTNPQAIRDAHCRFLLSGADVISTATYQASVEGFMDHLNSEGAKELIMSGVQLAKEAVESFQCSSGRRCPLVAGSLGPYGAFLHNGSEYTGDYAEKMSVQELKAWHRPQVECLAAAEADVLAFETIPSIKEAEALVELLKEF-----PNTKAWLSLSCKD-VKRLSDGSLFRDAVQIARSEQLIAVGVNCC-PPELVEPLLDSARTLPEISWVVYPNSGESWDPEQGWCTSEALLEMSGTWVKQG-AALIGGCCRISPAHVAKLRRHLKGSRGSPTSEPRPKCKPS--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
C4XYV2 Putative uncharacterized p -------------------------------------------------------------------------------MSFKEALKKSVLVQDGALGTQLEALIPLDDPHSVKGSPLWSTNA-------LLYSPELISSIHKQYVEAGADMIITATYQASPQTLSKYENMDQAKKVWTKSV----ECALEATRTHPEKKIFIGGSIGPYGAYLANGAEYSGDY-GDISSDQLMDYHRDIVRFYAETKVDVIAFETVPNFAEVQAIFSLIEQMFNANLH-KEFYVSLSCKDADH-LVDGTPLEQVIRYILSKNLVGIGCNC-VPFEIVSDFIETVNRVCQLSLLVYPNLGEPTDTANYRSSTEKWASSVAKWALYSNVRVIGGCCSTGPAEIAQIKDVVEKIKS---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
XP_001845705.1 numb-associated kinase [Cu ----------------------------------------------------------------------------PVKSRSLKMTSKRIIVIDGGFSTQLATH---VGQTTLDKDPLWSS-------RYNATNPNAVIETHLDFLKAGADCILTNTYQASIEGYMDFLNEEDSIKLIKTAVELAKLARTRYLAEKIENKPWVVGSIGPYGAHLHDGSEYTGAYADTVPYARIQKWHRQRINAVLEAGVDALAIETIPCRKEAEALLELLTTEHPT----VRFWVSFQCKDGVNTARGENFAETAARALKNPNLLAIGVNC-LHPVHAVQLLKTANERRKIPLIVYPNSGEIWDNGVWEEDCVPLETYVPQFVEYG-VKFVGGCCRTTAQDIKRIKKTVIN------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Pairwise Alignments
YP_001591292.1 B12-dependent methionine synthase [Salmonella enterica subsp. enterica serovar Paratyphi B str. SPB7] Length: 1301. Score: 3097. Identity: 100%. E-value: 1E-200. Query: 1 MTSQDARWRCAYQAYALGAAKVICRLDKALASPSGKATEVGGKLNMSHVARCSLFRQHALCQYGSLRGALSGASVSSKVEQLRAQLNERILVLDGGMGTMIQSYRLHEEDFRGERFADWPCDLKGNNDLLVLSKPEVIAAIHNAYFEAGADIIETNTFNSTTIAMADYRMESLSAEINYAAAKLARACADEWTVRTPNKPRYVAGVLGPTNRTASISPDVNDPAFRNITFDQLVAAYRESTKALVEGGADLILIETVFDTLNAKAAVFAVKEEFEALGVDLPIMISGTITDASGRTLSGQTTEAFYNSLRHAEALTFGLNCALGPDELRQYVQELSRIAECYVTAHPNAGLPNAFGEYDLDADTMAKQIREWAEAGFLNIVGGCCGTTPEHIAAMSRAVAGLPPRQLPDIPVACRLSGLEPLNIGDDSLFVNVGERTNVTGSAKFKRLIKEEKYSEALDVARQQVESGAQIIDINMDEGMLDAEAAMVRFLSLIAGEPDIARVPIMIDSSKWEVIEKGLKCIQGKGIVNSISMKEGVEAFIHHAKLLRRYGAAVVVMAFDEQGQADTRERKIEICRRAYKILTEEVGFPPEDIIFDPNIFAVATGIEEHNNYAQDFIGACEDIKRELPHALISGGVSNVSFSFRGNDPVREAIHAVFLYYAIRNGMDMGIVNAGQLAIYDDLPAELRDAVEDVILNRRDDGTERLLELAEKYRGSKTDEAANAQQAEWRSWDVKKRLEYSLVKGITEFIEQDTEEARQQAARPIEVIEGPLMDGMNVVGDLFGEGKMFLPQVVKSARVMKQAVAYLEPFIEASKEKGSSNGKMVIATVKGDVHDIGKNIVGVVLQCNNYEIVDLGVMVPAEKILRTAREVNADLIGLSGLITPSLDEMVNVAKEMERQGFTIPLLIGGATTSKAHTAVKIEQNYSGPTVYVQNASRTVGVVAALLSDNQRDDFVARTRKEYETVRIQHARKKPRTPPVTLEAARDNDLAFDWERYTPPVANRLGVQEVEASIETLRNYIDWTPFFMTWSLAGKYPRILEDEVVGVEAQRLFKDANDMLDKLSAEKLLNPRGVVGLFPANRVGDDIEIYRDETRTHVLTVSHHLRQQTEKVGFANYCLADFVAPRLSGKADYIGAFAVTGGLEEDALADAYEAQHDDYNKIMVKAIADRLAEAFAEYLHERVRKVYWGYAPNESLSNDELIRENYQGIRPAPGYPACPEHTEKGTIWQLLDVEKHTGMKLTESFAMWPGASVSGWYFSHPESKYFAVAQIQRDQVTDYAFRKGMSVEDVERWLAPNLGYDAD Sbjct: 1 MTSQDARWRCAYQAYALGAAKVICRLDKALASPSGKATEVGGKLNMSHVARCSLFRQHALCQYGSLRGALSGASVSSKVEQLRAQLNERILVLDGGMGTMIQSYRLHEEDFRGERFADWPCDLKGNNDLLVLSKPEVIAAIHNAYFEAGADIIETNTFNSTTIAMADYRMESLSAEINYAAAKLARACADEWTVRTPNKPRYVAGVLGPTNRTASISPDVNDPAFRNITFDQLVAAYRESTKALVEGGADLILIETVFDTLNAKAAVFAVKEEFEALGVDLPIMISGTITDASGRTLSGQTTEAFYNSLRHAEALTFGLNCALGPDELRQYVQELSRIAECYVTAHPNAGLPNAFGEYDLDADTMAKQIREWAEAGFLNIVGGCCGTTPEHIAAMSRAVAGLPPRQLPDIPVACRLSGLEPLNIGDDSLFVNVGERTNVTGSAKFKRLIKEEKYSEALDVARQQVESGAQIIDINMDEGMLDAEAAMVRFLSLIAGEPDIARVPIMIDSSKWEVIEKGLKCIQGKGIVNSISMKEGVEAFIHHAKLLRRYGAAVVVMAFDEQGQADTRERKIEICRRAYKILTEEVGFPPEDIIFDPNIFAVATGIEEHNNYAQDFIGACEDIKRELPHALISGGVSNVSFSFRGNDPVREAIHAVFLYYAIRNGMDMGIVNAGQLAIYDDLPAELRDAVEDVILNRRDDGTERLLELAEKYRGSKTDEAANAQQAEWRSWDVKKRLEYSLVKGITEFIEQDTEEARQQAARPIEVIEGPLMDGMNVVGDLFGEGKMFLPQVVKSARVMKQAVAYLEPFIEASKEKGSSNGKMVIATVKGDVHDIGKNIVGVVLQCNNYEIVDLGVMVPAEKILRTAREVNADLIGLSGLITPSLDEMVNVAKEMERQGFTIPLLIGGATTSKAHTAVKIEQNYSGPTVYVQNASRTVGVVAALLSDNQRDDFVARTRKEYETVRIQHARKKPRTPPVTLEAARDNDLAFDWERYTPPVANRLGVQEVEASIETLRNYIDWTPFFMTWSLAGKYPRILEDEVVGVEAQRLFKDANDMLDKLSAEKLLNPRGVVGLFPANRVGDDIEIYRDETRTHVLTVSHHLRQQTEKVGFANYCLADFVAPRLSGKADYIGAFAVTGGLEEDALADAYEAQHDDYNKIMVKAIADRLAEAFAEYLHERVRKVYWGYAPNESLSNDELIRENYQGIRPAPGYPACPEHTEKGTIWQLLDVEKHTGMKLTESFAMWPGASVSGWYFSHPESKYFAVAQIQRDQVTDYAFRKGMSVEDVERWLAPNLGYDAD B9ZN58 Methionine synthase - Thioalkalivibrio sp. K90mix Length: 1302. Score: 2733. Identity: 64%. E-value: 1E-200. Query: 54 LFRQHALCQYGSLRGALSGAS--------VSSKVEQLRAQLNERILVLDGGMGTMIQSYRLHEEDFRGERFADWPCDLKGNNDLLVLSKPEVIAAIHNAYFEAGADIIETNTFNSTTIAMADYRMESLSAEINYAAAKLARACADEWTVRTPNKPRYVAGVLGPTNRTASISPDVNDPAFRNITFDQLVAAYRESTKALVEGGADLILIETVFDTLNAKAAVFAVKEEFEALGVDLPIMISGTITDASGRTLSGQTTEAFYNSLRHAEALTFGLNCALGPDELRQYVQELSRIAECYVTAHPNAGLPNAFGEYDLDADTMAKQIREWAEAGFLNIVGGCCGTTPEHIAAMSRAVAGLPPRQLPDIPVACRLSGLEPLNIGDDSLFVNVGERTNVTGSAKFKRLIKEEKYSEALDVARQQVESGAQIIDINMDEGMLDAEAAMVRFLSLIAGEPDIARVPIMIDSSKWEVIEKGLKCIQGKGIVNSISMKEGVEAFIHHAKLLRRYGAAVVVMAFDEQGQADTRERKIEICRRAYKILTEEVGFPPEDIIFDPNIFAVATGIEEHNNYAQDFIGACEDIKRELPHALISGGVSNVSFSFRGNDPVREAIHAVFLYYAIRNGMDMGIVNAGQLAIYDDLPAELRDAVEDVILNRRDDGTERLLELAEKYRGSKTDEAANAQQAEWRSWDVKKRLEYSLVKGITEFIEQDTEEARQQAARPIEVIEGPLMDGMNVVGDLFGEGKMFLPQVVKSARVMKQAVAYLEPFIEASKEKGSSNGKMVIATVKGDVHDIGKNIVGVVLQCNNYEIVDLGVMVPAEKILRTAREVNADLIGLSGLITPSLDEMVNVAKEMERQGFTIPLLIGGATTSKAHTAVKIEQNYSGPTVYVQNASRTVGVVAALLSDNQRDDFVARTRKEYETVRIQHARKKPRTPPVTLEAARDNDLAFDWERYTPPVANRLGVQEVE--------------------ASIETLRNYIDWTPFFMTWSLAGKYPRILEDEVVGVEAQRLFKDANDMLDKLSAEKLLNPRGVVGLFPANRV-GDDIEIYRDETRTHVLTVSHHLRQQTEK-VGFANYCLADFVAPRLSGKADYIGAFAVTGGLEEDALADAYEAQHDDYNKIMVKAIADRLAEAFAEYLHERVRKVYWGYAPNESLSNDELIRENYQGIRPAPGYPACPEHTEKGTIWQLLDVEKHTGMKLTESFAMWPGASVSGWYFSHPESKYFAVAQIQRDQVTDYAFRKGMSVEDVERWLAPNLGYD Sbjct: 11 TAPQGGFPPGCTALPGHDNESIQHNGVPHMTATRNDIEKALKERILILDGGMGTTIQLYKLEEADYRGERFKDWESDLKGNNDLLSLTRPDIIEQIHNDYLEAGADIIEANTFNGTRIAMADYHMEDLVPELNRESAKLARKAADAWTEKTPDKPRYVAGILGPTNRTASISPDVNDPGARNVDFDTLVESYKEAAEALVEGGVDILLIETVFDTLNAKAAIFAVKTLEDELGKELPIMISGTITDASGRTLSGQTTEAFWNSVRHANPVSIGLNCALGAKEMRQYVEELSRIADTHVSAHPNAGLPNEFGDYDESPEQMAADVGPWAEQGLLNIIGGCCGTLPEHIRAMREAVEKFPPRKVPEIAPACRLSGLEPCNITDDSLFVNVGERTNVTGSRKFLRLIQNEEYDVALEVALNQVEGGAQIIDINMDEGMLESQDAMVRFLNLLAGEPDIARVPVMIDSSKFEIIEAGLKCVQGKAVVNSISMKEGEENFIKQAQLCRRYGAAIVVMAFDEDGQADNEDRRVEICTRAYRLLTEKVGFPAEDIIFDPNIFAVATGIEEHNNYGVDFIEATRRIKQDLPHALVSGGVSNVSFSFRGNEPVREAIHAVFLYHAIKAGMDMGIVNAGQLAVYDDIDEKLKEAVEDVVLNRRDDATERLLDLSEEYKGQGG--GKKEENLEWREWEVTKRLEHSLVKGIDTYVVEDTEEARQQYDRPIQVIEGPLMDGMNVVGDLFGEGKMFLPQVVKSARVMKKAVAHLIPYIEAEKTGTENNGKILMATVKGDVHDIGKNIVGVVLQCNNFEVIDIGVMQPGAEILKAAKEHDVDVIGLSGLITPSLEEMANFAADLEREGMTTPLMIGGATTSRAHTAVKIEPNYSGPVVWVKDASRAVGVAQSLISPELRENYAAEIREEYEKLRVQNAGRKKKTQWVTLEKARANKPQIDWSSYTPTKPKALETDKLPGEPKVLHPHGDGSVLLRFDDFDLNEVRNFIDWTPFFHSWQLHAAYPRILDDEKVGEEARKLFKDGQEMLDRMIEEKWVTLRGVVGFFPANTVNDDDIEVYTDESRSKVLKKLHHLRQQTEKRRGQPSHSLADFLMPKEAGGPDYLGAFAVSAGGDVDAKAEEYEKANDDYHAILVKSLADRLAEAFAECMHQYVRKHYWGYVPDEALENEDLIDEKYQGIRPAPGYPACPEHTEKGTLWELLQADEHADMTLTESYAMLPVSAVSGWYFAHPESRYFGLGKVNRDQVEDYAKRKGMSFEEAERWLAPNIGYD ZP_01044513.1 5-methyltetrahydrofolate--homocysteine methyltransferase [Nitrobacter sp. Nb-311A] Length: 1321. Score: 2611. Identity: 60%. E-value: 1E-200. Query: 69 ALSGASVSSKVEQLRAQLNERILVLDGGMGTMIQSYRLHEEDFRGERFADWPCDLKGNNDLLVLSKPEVIAAIHNAYFEAGADIIETNTFNSTTIAMADYRMESLSAEINYAAAKLARACADEWTVRTPNKPRYVAGVLGPTNRTASISPDVNDPAFRNITFDQLVAAYRESTKALVEGGADLILIETVFDTLNAKAAVFAVKEEFEALGVDLPIMISGTITDASGRTLSGQTTEAFYNSLRHAEALTFGLNCALGPDELRQYVQELSRIAECYVTAHPNAGLPNAFGEYDLDADTMAKQIREWAEAGFLNIVGGCCGTTPEHIAAMSRAVAGLPPRQLPDIPVACRLSGLEPLNIGDDSLFVNVGERTNVTGSAKFKRLIKEEKYSEALDVARQQVESGAQIIDINMDEGMLDAEAAMVRFLSLIAGEPDIARVPIMIDSSKWEVIEKGLKCIQGKGIVNSISMKEGVEAFIHHAKLLRRYGAAVVVMAFDEQGQADTRERKIEICRRAYKILTEEVGFPPEDIIFDPNIFAVATGIEEHNNYAQDFIGACEDIKRELPHALISGGVSNVSFSFRGNDPVREAIHAVFLYYAIRNGMDMGIVNAGQLAIYDDLPAELRDAVEDVILNRRDDGTERLLELAEKYRGSKTDEAANAQQAEWRSWDVKKRLEYSLVKGITEFIEQDTEEARQQAARPIEVIEGPLMDGMNVVGDLFGEGKMFLPQVVKSARVMKQAVAYLEPFIEASKEKG----------SSNGKMVIATVKGDVHDIGKNIVGVVLQCNNYEIVDLGVMVPAEKILRTAREVNADLIGLSGLITPSLDEMVNVAKEMERQGFTIPLLIGGATTSKAHTAVKIEQNY-SGPTVYVQNASRTVGVVAALLSDNQRDDFVARTRKEYETVRIQHARKKPRTPPVTLEAARDNDLAFDWERYTPPVANRLGVQEV-EASIETLRNYIDWTPFFMTWSLAGKYPRILEDEVVGVEAQRLFKDANDMLDKLSAEKLLNPRGVVGLFPANRVGDDIEIYRDETRTHVLTVSHHLRQQTEKV-GFANYCLADFVAPRLSGKADYIGAFAVTGGLEEDALADAYEAQHDDYNKIMVKAIADRLAEAFAEYLHERVRKVYWGYAPNESLSNDELIRENYQGIRPAPGYPACPEHTEKGTIWQLLDVEKHTGMKLTESFAMWPGASVSGWYFSHPESKYFAVAQIQRDQVTDYAFRKGMSVEDVERWLAPNLGY Sbjct: 30 TRVTNSSNPIADKFRALARERILVLDGAMGTMIQDRGFDEAAFRGERFKDFHRDVRGNNDLLILTQPQAIEDIHTQYLRAGADLVATNTFSSTSIAQADYDMADLVYDLNREGARLARSAAEKVSAED-GKPRFVVGAIGPTNRTASISPDVANPGYRAVTFDDLRKAYGEQINGLLDGGADLLLVETIFDTLNAKAALYAIAEIGEQRGIDIPVMISGTITDKSGRLLSGQLPEAFWHSVRHAGPITIGFNCALGAEDLRAHVAEIGRVADTLVCAYPNAGLPNEFGQYDESPDYMARLIGEFAQTGLVNVVGGCCGTTPDHIAAIAAAVAPHKPRVVPVIAPRLRLSGLEPFSLTSDIPFVNVGERTNVTGSARFRNLIKAGDYAAALDVARNQVENGAQIIDVNMDEGLLDSEAAMVTFLNLIAAEPDIARVPVMVDSSKFSVIEAGLKC