P0ABQ4 is a cross-reference for 3DAU-A, which is represented by C2B0F4 in NRDB40.
| Set | Shortcuts | Acc.No. | Identifier | Database | Description |
|---|---|---|---|---|---|
| NRDB | IBP | 3DAU-A | 3DAU-A | PDB | dihydrofolate reductase - [ escherichia coli k12] |
| NRDB40 | IBP | C2B0F4 | C2B0F4_9ENTR | UniProt | Putative uncharacterized protein - Citrobacter youngae ATCC 29220 |
PSI-BLAST Results for C2B0F4 against NRDB40
Filtering conditions for the hit sequences
- E-value is less than
Matches:
Match Overview
| Score | E-value | Shortcuts | Acc.No. | Description | ||
|---|---|---|---|---|---|---|---|
  | - | IBP | C2B0F4 | Putative uncharacterized protein - Citrobacter youngae ATCC 29220 | |||
  | 514 | 3E-50 | IBP | YP_001125779.1 | dihydrofolate reductase [Geobacillus thermodenitrificans NG80-2] | ||
| 508 | 1E-49 | IBP | ZP_01201001.1 | dihydrofolate reductase [Flavobacteria bacterium BBFL7] | ||
| 496 | 3E-48 | IBP | ZP_02180882.1 | dihydrofolate reductase [Flavobacteriales bacterium ALC-1] | ||
| 494 | 6E-48 | IBP | YP_747242.1 | dihydrofolate reductase [Nitrosomonas eutropha C91] | ||
| 490 | 2E-47 | IBP | YP_001023231.1 | dihydrofolate reductase [Methylibium petroleiphilum PM1] | ||
| 486 | 4E-47 | IBP | ZP_02478257.1 | dihydrofolate reductase [Haemophilus parasuis 29755] | ||
| 485 | 6E-47 | IBP | YP_128633.1 | putative dihydrofolate reductase [Photobacterium profundum SS9] | ||
| 485 | 6E-47 | IBP | ZP_02160204.1 | dihydrofolate reductase type I; trimethoprim resistance [Kordia algicida OT-1] | ||
| 480 | 2E-46 | IBP | YP_442211.1 | dihydrofolate reductase [Burkholderia thailandensis E264] | ||
| 478 | 4E-46 | IBP | YP_574617.1 | dihydrofolate reductase [Chromohalobacter salexigens DSM 3043] | ||
| 477 | 6E-46 | IBP | NP_296351.1 | dihydrofolate reductase [Deinococcus radiodurans R1] | ||
| 475 | 8E-46 | IBP | Q39687 | Dihydrofolate reductase-thymidylate synthetase - Daucus carota | ||
| 475 | 9E-46 | IBP | ZP_05671924.1 | dihydrofolate reductase [Enterococcus faecium 1,231,408] | ||
| 475 | 1E-45 | IBP | YP_001101808.1 | dihydrofolate reductase [Yersinia ruckeri] | ||
| 473 | 1E-45 | IBP | YP_001580403.1 | dihydrofolate reductase [Burkholderia multivorans ATCC 17616] | ||
| 473 | 2E-45 | IBP | ZP_02906323.1 | Dihydrofolate reductase [Burkholderia ambifaria MEX-5] | ||
| 473 | 2E-45 | IBP | YP_810587.1 | dihydrofolate reductase [Oenococcus oeni PSU-1] | ||
| 468 | 7E-45 | IBP | YP_001174482.1 | dihydrofolate reductase [Pseudomonas stutzeri A1501] | ||
| 465 | 1E-44 | IBP | YP_001599935.1 | dihydrofolate reductase [Neisseria meningitidis 053442] | ||
| 465 | 1E-44 | IBP | YP_003089177.1 | Dihydrofolate reductase [Dyadobacter fermentans DSM 18053] | ||
| 466 | 1E-44 | IBP | ZP_01863662.1 | phosphoribosylaminoimidazole carboxylase ATPase subunit [Erythrobacter sp. SD-21] | ||
| 446 | 2E-42 | IBP | ZP_04983084.1 | dihydrofolate reductase type I [Francisella tularensis subsp. holarctica 257] | ||
| 446 | 2E-42 | IBP | B9H4E7 | Dihydrofolate reductase-thymidylate synthase - Populus trichocarpa | ||
| 445 | 3E-42 | IBP | B9H4E4 | Dihydrofolate reductase-thymidylate synthase - Populus trichocarpa | ||
| 441 | 8E-42 | IBP | C1YEX4 | Dihydrofolate reductase - Nakamurella multipartita DSM 44233 | ||
| 437 | 2E-41 | IBP | YP_002566814.1 | dihydrofolate reductase region [Halorubrum lacusprofundi ATCC 49239] | ||
| 437 | 3E-41 | IBP | YP_001832848.1 | dihydrofolate reductase [Beijerinckia indica subsp. indica ATCC 9039] | ||
| 434 | 5E-41 | IBP | YP_804567.1 | dihydrofolate reductase [Pediococcus pentosaceus ATCC 25745] | ||
| 434 | 6E-41 | IBP | ZP_02432762.1 | hypothetical protein CLOSCI_03017 [Clostridium scindens ATCC 35704] | ||
| 429 | 2E-40 | IBP | YP_818239.1 | dihydrofolate reductase [Leuconostoc mesenteroides subsp. mesenteroides ATCC 8293] | ||
| 427 | 3E-40 | IBP | B9R7Y4 | Bifunctional dihydrofolate reductase-thymidylate synthase, putative - Ricinus communis | ||
| 425 | 6E-40 | IBP | ZP_04564410.1 | dihydrofolate reductase [Mollicutes bacterium D7] | ||
| 425 | 6E-40 | IBP | YP_001598129.1 | Tri [Salmonella enterica subsp. enterica serovar Choleraesuis] | ||
| 424 | 7E-40 | IBP | C2MBL2 | Dihydrofolate reductase - Porphyromonas uenonis 60-3 | ||
| 424 | 7E-40 | IBP | C1X560 | Dihydrofolate reductase - Kytococcus sedentarius DSM 20547 | ||
| 423 | 1E-39 | IBP | YP_002139599.1 | dihydrofolate reductase region [Geobacter bemidjiensis Bem] | ||
| 421 | 2E-39 | IBP | YP_832498.1 | dihydrofolate reductase [Arthrobacter sp. FB24] | ||
| 419 | 3E-39 | IBP | C1W4R8 | Dihydrofolate reductase - Jonesia denitrificans DSM 20603 | ||
| 418 | 4E-39 | IBP | NP_870608.1 | dihydrofolate reductase [Rhodopirellula baltica SH 1] | ||
| 418 | 4E-39 | IBP | NP_492364.1 | DiHydroFolate Reductase family member (dhfr-1) [Caenorhabditis elegans] | ||
| 417 | 5E-39 | IBP | YP_877291.1 | dihydrofolate reductase [Clostridium novyi NT] | ||
| 417 | 6E-39 | IBP | YP_358159.1 | dihydrofolate reductase [Pelobacter carbinolicus DSM 2380] | ||
| 416 | 6E-39 | IBP | ZP_03945215.1 | dihydrofolate reductase [Lactobacillus fermentum ATCC 14931] | ||
| 416 | 7E-39 | IBP | ZP_03487511.1 | hypothetical protein EUBIFOR_00069 [Eubacterium biforme DSM 3989] | ||
| 414 | 1E-38 | IBP | ZP_02430941.1 | hypothetical protein CLOSCI_01157 [Clostridium scindens ATCC 35704] | ||
| 413 | 2E-38 | IBP | ZP_00999790.1 | Dihydrofolate reductase [Oceanicola batsensis HTCC2597] | ||
| 410 | 3E-38 | IBP | C2E963 | Dihydrofolate reductase - Lactobacillus ruminis ATCC 25644 | ||
| 408 | 5E-38 | IBP | B8BKI9 | Putative uncharacterized protein - Oryza sativa subsp. indica | ||
| 407 | 7E-38 | IBP | NP_001067911.1 | Os11g0484400 [Oryza sativa (japonica cultivar-group)] |
Stacked Multiple Aligment
1 1 1 1 1 1 1 1 1 1 2
1 2 3 4 5 6 7 8 9 0 1 2 3 4 5 6 7 8 9 0
1234567890123456789012345678901234567890123456789012345678901234567890123456789012345678901234567890123456789012345678901234567890123456789012345678901234567890123456789012345678901234567890123456789012345
The representative sequence for the query: MLGVHLEVADSPAEQKIFLHIFLWLVDERLRFPYSGDNFFVSGKHSMISLIAALAVDRVIGMENAMPWNLPADLAWFKRNTLNKPVVMGRHTWESIGRPLPGRKNIVISSKPGTDDRVQWVKSVDEAIAACGDEPEIMVIGGGRVYEQFLPKAQKLYLTHIDAEVEGDTHFPDYEPDDWESVFSEFHDADAQNSHSYCFEILERR
C2B0F4 Putative uncharacterized p MLGVHLEVADSPAEQKIFLHIFLWLVDERLRFPYSGDNFFVSGKHSMISLIAALAVDRVIGMENAMPWNLPADLAWFKRNTLNKPVVMGRHTWESIGRPLPGRKNIVISSKPGTDDRVQWVKSVDEAIAACGDEPEIMVIGGGRVYEQFLPKAQKLYLTHIDAEVEGDTHFPDYEPDDWESVFSEFHDADAQNSHSYCFEILERR
YP_001125779.1 dihydrofolate reductase [G ----------------------------------------CKGEKTMISHIVAMDENRVIGKDNQLPWHLPADLAYFKRVTMGHAIVMGRKTFEAIGRPLPGRDNVVVTRNPQFPEGCLVLHSLEEVKQIAARGEEVFIIGGAELFKATMPIADRLYVTNIFASFPGDTFYPPISEKEWKVVSYTPGVKDEKNPYEHAFLIYERK
ZP_01201001.1 dihydrofolate reductase [F --------------------------TKSNPLPETKIINTPVSKKRVITMIAAAGANNELGKDGDLVWHLPDDFKRFKSLTTGHHIIMGRKTFESFPKPLPNRTHIILTRDANYKDGGIVVHDLSTALAAASSDEEPFIIGGGEIYKLGLEIADRIELTRVHGSFDVDTYFPEFDEKQWKLIRTEHHPADDKHEYAFDFETWER-
ZP_02180882.1 dihydrofolate reductase [F ----------------------------------------------ELTIIVAAGEKNAIGKDNDLIWHLSDDLKRFKKLTNGHHIIMGRKTFESFPKPLPNRIHIVITRQSDYPDGVIVVNSLEDALDAARKDNQPFIIGGGEIYKQSINRVDKLEITRVHSTFEADTFFPKIDTSIWREVSRTTHDADEKHAHAFSFITYLKK
YP_747242.1 dihydrofolate reductase [N ----------------------------------------LQPATSRLAILAAISANRVIGLNNSLPWHLPADLKHFKQLTTGHIVVMGRRTFDSIGKPLPDRTNVVLSRQHVLDPGIITAHSIQEVLDHANDDRQIFVIGGAELYRQTLPLCQRLYLTEIQEDFEGDTFFPEYDHDDWQEISREIHHETGGSGLEYHFVMLDHK
YP_001023231.1 dihydrofolate reductase [M ---------------------------------------------MDLAIIAACARNGVIGRNNDLPWRLPEDLAHFRSTTGGWPVIMGRLTWESLPRPLPGRRNIIVSRGGVRPKGVDVVASLEAALELVQAERRAFVIGGARLYEAALPLADELFLTEIDEDFEGDVYFPEFDRSAFVEHHRMRRQAEAPNTFTYSFAHYRRK
ZP_02478257.1 dihydrofolate reductase [H ------------------------------------------GNRMKISVIVARTLNKVIGKDNAMPWHLPVDLAWFRENTLGKPVIMGRKTYESIGRLLPKRPNIILSRSGFAIDGAYSAISLEQAVELAKNSDEIMIIGGGELFKQTMPFADKLYLTEIQANIEGDTFF-EFDETQWQQIAEKWSEIDEQNSYRCRFMILDK-
YP_128633.1 putative dihydrofolate red ---------------------------------------YLRRYEVKISMIAAMAKDRVIGKDNAMPWHLPADFAWFKKSTLGKPIVMGRKTFESIGRPLPGRLNIVISRNPEFSEGVTVVADIEAAKHAAGDIGELMVIGGGSIYEACLPSADRLYLTFIDLDVDGDTCFPDWGEG-WIKSYTEHYSADEKNAHDMQFVILER-
ZP_02160204.1 dihydrofolate reductase ty -----------------------------------------------LVIIVAAAENNVIGKDNQLIWHLSDDLKRFKKLTSGHHIIMGRKTFESFPKPLPNRTHIVITRQKDYPKGVIVVHTMKEAVSVATSDAEPYVIGGGEIYKQALPFATKIELTRVHHEFEGDAYFPEIDKKDWKETNNVFHTKDDKHEYEFSFLTYER-
YP_442211.1 dihydrofolate reductase [B ------------------------------------------------------ARNGVIGRDNRLPWKLPEDLAFFKRTTMGAPIVMGRKTHESIGRPLPGRRNIVVTRDAARRDGCDTATSLGDALALAERDGEAFLIGGAQLYAEGLRHADKLIVTEIDQDFEGDASFPAPDPAQWEAVSRDAHRAAPPNDFAYAFVVYRRK
YP_574617.1 dihydrofolate reductase [C -----------------------------------------------IALVAAMSRNRVIGVDNKLPWHLPEDLKFFKAVTMSKPLVMGRKTFESIGRPLPGRLNIVVTRDRGYHDGIRVCHDLASALDMADGQEDICVIGGGEIFAEALPCATRLYLTEVDIEVEGDAWFPAFDAREWQETQRVP-GQGGEGKPEYAFVHYTRR
NP_296351.1 dihydrofolate reductase [D -----------------------------------------------IVAIAAQTENRVIGRDGGMPWHLPADFAHFRALSVGKPNIMGRKVFDTLRRPLPERVNIVLTRNENLKDGCLIAHSPEEALQLAGDAPEIAIIGGEEIYRLYWDRLTRLEMTLIHAELDGDTFFPEIGP-EWELAQETFRPADEKNRYDLTFQTWRRR
Q39687 Dihydrofolate reductase-th -----------------------YMASERLANPTNGSGITRPDPQRTYQVVVAATQNMGIGKDGKLPWRLPSDMKFFKDVTMRNAVIMGRKTWESIPRPLPGRLNVVLTRSGSFDENVVICGSMISALELLAGSPKVFVIGGGQIYREALPGCDAVHITEIEEHIECDTFIPLLDESVFQPWYSSFPLV--ENKIRYCFTTYVR-
ZP_05671924.1 dihydrofolate reductase [E ----------------------------------------------MLAAIWAQDENGLIGKEDRLPWRLPNDLKFFKQMTEANTLVMGRKTFEGMGRPLPNRQTIVLTRDSSYKEGVHVMHSVEDVLALEKETDGIFFIGGSAVYQEFLPFCTILYRTVIHHVFDGDAYFPPVDWSDWSLINTSQGEMDEKNRYPHQFETYQR-
YP_001101808.1 dihydrofolate reductase [Y -----------------------------------------------ISLILAMADNGTIGDKNALPWHLPNDLQFLKKSTMGKPIVMGRKTYQSIGRPLPGRTNVVISRSLEKEPGCLIYSDLSVAIAALKKEPEIMIMGGAQIYRAALPMMDRLYLTHVHANIEGDTQMPPFDFSHATLIFEEKHFKDEKNRYDYTFEIWDFK
YP_001580403.1 dihydrofolate reductase [B ------------ARRRSTPRGGAPVPVESAPFRFFLSPTFMTT----LTLIVARARNGIIGRDNQLPWKLPEDLAFFKRTTMGAPIVMGRKTHESIGRPLPGRRNIVVTRDASRRDGCDTVTSLADALALAARDGEAFLIGGAQLYAEGLAQADKLIVTEIDADFEGDASFPAPDPAQWQEVSRDAHQAATPNTFGYAFVVYARK
ZP_02906323.1 Dihydrofolate reductase [B ---------------------------ESAPFRFSSSPIFMTT----LTLIVARARNGIIGRDNQLPWKLPEDLAFFKRTTMGAPIVMGRKTHESIGRPLPGRRNIVVTRDAARRDGCDTVTSLADALALAARDGEAFLIGGAQLYAEGRALADKLIVTEIDADFDGDASFPAPDPAHWHEVSREPHQAAAPNTFGYAFVVYARK
YP_810587.1 dihydrofolate reductase [O ----------------------------------------------MITSIWAQSKNNVIGRNNHLPWSLPDDLKFFRQETKNKAVVMGRKTYESFGKALPKRLNIILTSNMDFDPEVKIVHSPIEAVNTAKEQHPLYVIGGASVYESFMNMADRLLITLVDANIKGDTFAPNFSEKSFSLVSQCHHAQDKKHAYSFDFLTYERK
YP_001174482.1 dihydrofolate reductase [P ---------------------------------------AMNQTRLPLAMIAALAERHVIGRDNIMPWHLPADLRHFKAMTLGKPIIMGRKTWDSLGRPLPGRLNLVVSRQADLQDGAETFTDLDAALVRAEQWDELMLIGGAQLYAQALGQAQRLYLTRIDAQPEGDAFFPVFDEHEWQCIDSQPHPAEGE-APAYRFETWQRR
YP_001599935.1 dihydrofolate reductase [N ------------------------------------RRHFCGGNMLKITLIAACAENLCIGAGNAMPWHIPEDFAFFKAYTLGKPVIMGRKTWESLPKPLPGRRNIVISRQADYAAGAETAASLEAALALCAGAEEAVIMGGAQIYGQAMPLATDLRITEVDLSVEGDAFFPEIDRTHWKEAGRTERRVSSK-GTRYAFVHYLR-
YP_003089177.1 Dihydrofolate reductase [D -------------------------------------------TQMKISIIVAAAENGAIGRDNQLLWRLSDDLKRFKQLTLGHPMIMGRKTFESIGKPLPGRTSIVITRNANFADGVVVVHSLDEALEKAKEIDEVCIVGGGEIYEQSQAIATHIYLTKVHTSVVGDTFFSIREPEAWTETERISHEPDERHIFPFEFINYIKK
ZP_01863662.1 phosphoribosylaminoimidazo ---------------------------ERGPQDGPHHPDLPRHPRMSLFLIYARAANGAIGKQGRLPWHLPADLKRFKALTMGKPMIMGRKTFESLPGLLPGRRHIVLTRKERWDTGAEVVRSVGEAVAKA-GEGDIAVIGGAAIFDVFMPLAKKVELTEIHRDFDGDVFMPPLGP-EWDLAGTEDFEADGDT-PAYSFHTYRR-
ZP_04983084.1 dihydrofolate reductase ty -----------------------------LKYIKMTKNRFLK----MISLIVAYDKNFGIGKENTLAWKLSEDLKNFKKITENNYIVMGRKTFESIGRPLPNRKNIILTRNKDYKQDCLIINSTQDILNFAESKPEIFIIGGAQIYKEFLKYADRLYITEVDAEMDLDAFFPQWDKSKYKRIGHKQFKKNDKNEFDFTFSIFEK-
B9H4E7 Dihydrofolate reductase-th -------------------------------------------PMRSYQVVVAATRDMGIGKDGKLPWRLPSDLKFFKEVTKQNAILMGRKTWESIPRPLPDRLNVVLTRSIEDEENVITCGSISSALELLAETPKVFVIGGGQILRETLPGCDAIHVTEIESSVECDTFIPSIDFSKFQPWYSSPPLV--ENGFRYSFVTY---
B9H4E4 Dihydrofolate reductase-th -------------------------------QPWFRRFTAIAGPMRSYQVVVAATRDMGIGKDGKLPWRLPCDLKFFKEITKQNAILMGRKTWESIPRPLPGRLNVVLTRSIEDEENVITCGSISSALELLAEAPKVFVIGGGQILRETLPGCDAIHVTEIETSVECDTFIPSIDFSKFQPWYSSPPLV--ENGIRYSFVTY---
C1YEX4 Dihydrofolate reductase - ---------------------------------------------PTVVLVAAVARNGVIGAAGTMPWHIPADLKRFKRLTMGHPMVMGRKTFESMG-LLPGRRSIVITRDPHWRPGAEVADSLDRAIALAQTDPVVMVVGGGEIYAQALPRADRLEITHLDLSAPGDTVFPAIDPALWAVTDREEAD-------GYAFVTYRRR
YP_002566814.1 dihydrofolate reductase re -----------------------------------------------LVLVAAVAENRVIGDDGGMPWHYPADLARFKRLTTGHPVIVGRATYESIGGPLPDRTSVVLTRDLDLPEGAVVANDLDEAVDLARGVDDVYVIGGATVYEQFLDRADRMVLTEVPEQPDGDTRFPDWDDEEWVETEREVVGADGERGGELAFVTYER-
YP_001832848.1 dihydrofolate reductase [B --------------------LFLRSLPNHKLDPALGDNDFP------LTIVAALADNRVIGLNQAMPWDLPGDRRHFRERTWGKPMLMGRKTFESIGRALPGRETIVLTRDETFAPGVLVAHDLEGALGLAHDWARIMLVGGGELFAALLPRVERLELTLVEGNPKGDTFFPPIDWSQWEEEKRSGPLQGPNDTISYQFVDYHRK
YP_804567.1 dihydrofolate reductase [P ----------------------------------------------MISMIWAEDLRHGIGKQQSIPWHIPGDMAFFKKTTSGNTVVMGRKTFDSIGKALPNRKNIVLSHHPTSLPDSVVVGSLSEAIFETHPNEKFYIIGGSHLYNALLSQADELLITRIQKDYQCEVLAPDITQNEFKLASSVEHESTERN-PAYTFETWIR-
ZP_02432762.1 hypothetical protein CLOSC --------------------------------------------MTMIGLIVARSKNNVIGKNGKIPWKIKGEQKQFRELTTNKTVIMGRKSYNEIGHPLANRLNIIVSNTANYTENLITVHSLNEAIQVA-GNKDIFVIGGYSLYKEALPIVDKMYITEIDIEVSGDVFFPQFNIDNFELSIGETFG----NDIKYTRTLYTRK
YP_818239.1 dihydrofolate reductase [L --------------------------------------------MTKIKMVWAEDRQHAIGKDGGIPWHMPDDLKLFRDETVNTLMIMGRPTWLSIGRPLPKRTTVVMTRQEDWTPEVKVIHSIEEAKNLAKEERDITIAGGAAVYREFMPYATDLVITRVDGVIDGDTFVDEVDLTQFQLKSSEPHAKDDNHDYAFVVERYER-
B9R7Y4 Bifunctional dihydrofolate ---------------------------------PRGNANMHLDRNRRYQVVVAATRDMGIGKDGKLPWRLPSDLKFFKELTKRNAVVMGRKTWESIPRPLPGRLNIVLTCSGTTAEDVLTCGSIPSALELLAEAPKVFFIGGGQILRKTIPGCDAIHITEIETSIECDTFIPVIDFSLFHPWYSSLPIV--ENNVRYSFATYVR-
ZP_04564410.1 dihydrofolate reductase [M ----------------------------------------------MINIIVATDEDLLIGKKNGMPWNVPEDLQHFKATTLNKTILMGLTTYQAIGRPLPNRKTIVVSFEPFEDERVEVRSSLEEVIEEYRSSGELFISGGASIYKQCLPIADQLLISRIPGKHEGETYFPNFDEYGYKLVAQKPFET-------FTLETYKR-
YP_001598129.1 Tri [Salmonella enterica s ----------------------------------------MNSESVRIYLVAAMGANRVIGNGPNIPWKIPGEQKIFRRLTEGKVVVMGRKTFESIGKPLPNRHTLVISRQANYRTGCVVVSTLSHAIALASEGNELYVAGGAEIYTLALPHAHGVFLSEVHQTFEGDAFFPMLNETEFELVSTETIQAV----IPYTHSVYAR-
C2MBL2 Dihydrofolate reductase - ---------------------------------------------MEIWIIVATARDRAIGRDGTMPWRLKDDLRRLKATTTGHAVIMGRHTWDSIGRPLPNRYNIVVSRTEGDAETHYVASTLEQALQHCAGYDRVYIMGGGVLYKSGLPYATHLNLTMVDTVVDADTHFPEINLSEWSKLEEAHYPADERNDYPVTQTLYKR-
C1X560 Dihydrofolate reductase - ------------------------------------PAVMTRGFSQSLTLVVAVARNGAIGRDGDLPWHLPGDLKHFKDTTMGGTMVMGRRTFESFPRPLPGRRHVVMTSDPTWLPGVLVARSWAEAL-LMAGDGEVFVVGGAGVFADALPVADRLVLTEVDQSPDADTFFPPVDPTVWHESSRTP-------GEGYAIVEYRR-
YP_002139599.1 dihydrofolate reductase re ---------------------------------------------MIISTIAALSDNRVIGADGGLPWDIPSDLTRFRSITMGHTVIMGRKTYESIGHPLLGRRNIVLTRKGSQIEGCEIARNVPAAIAAAEGEEEVFICGGGEVFQEALPLCQRLYLTVVHGNYRGDAFLPELPEGFVELHREEFPDTTPPS----SFVVLEK-
YP_832498.1 dihydrofolate reductase [A -----------------------------------------------VGLVWAQTTAGVIGKDGDMPWHLPEDMKHFTRLTTGHPVIMGRKTWLSFPRPLPGRTNIVVTRQEGWGDGAIAVKSLDDALQFAPGHETVWVLGGGEIFAQTLDIADVAVVTFIDSETDGDTYAPELGY-EWKLAASEPATLTSATGTRYRFTMWRR-
C1W4R8 Dihydrofolate reductase - ------------------------------------------AAKPQLSLIWAQSLNGVIGRSGTIPWHEPTDLAHFQKTTRGGVVIMGRHTWESLPTPLPQRVNIVLTSDRDYRPGARVVTTPQQALDLAHGHQAIWVIGGRQVYDTFMDYATQLIVTTVGTVIEGDTEAPRIPP---HFVPQEPHQLATHSDYEVTVTTWLR-
NP_870608.1 dihydrofolate reductase [R -----------------------------------------------ITAVVAATPNGVIGDDQDMPWRLSSDLKRFKKATMGGALIMGRKTFESIGRVLPGRQTIVLTRQGHWQPGTQTASGKSEAIALAAD-RRIFVVGGGQIYQQWFPLCTELWWTRVWANVSGDTRV-DLPLDEFELVSQTSFPVTAKDDYPTDWLRMRRR
NP_492364.1 DiHydroFolate Reductase fa --------------------------------------------MRKMNLIVAMDAEGGIGKNGVLPWRIKKDMQYFASVTKNNAVLMGRKCWESIPRPLAGRLNIVLSRQAQKSDDYIVVNSLEAAMKLLSEPPTIWNIGGAEIYDLALNLVDEIHLTRIFKNFEADVHLKSLDFSKMEEVSSENSEIFEENGLKFEFCKWK--
YP_877291.1 dihydrofolate reductase [C ----------------------------------------------MLSIVVAIGKNNVIGKDHSLPWHLPNDLKYFKKLTESKTMIMGRKTFQSLKALLPGRKHIILTKNKNFDSNVEIINKIDMLKPIINDKKEYFVIGGGEIFSLLLPYTEKIYMTKIHHNFIGDTFFPNINRYDWNTTKEIQGITDEKNVYNHTFLILNR-
YP_358159.1 dihydrofolate reductase [P ----------------------------------------VCTNSKQMTIVVAMTAERIIGRRGQLPWSIPEDLALFRRLTYGHTLVMGRRTFESIGRPLPGRFNIVVSRSMPPVEGLRVCRHFAEALQVAQGNGDIFFIGGCEIYRQALIVAGKLSVSWIRKNYPGDCRFPEYRSDDWLIEQEQDYS-------EFRHIIYRRR
ZP_03945215.1 dihydrofolate reductase [L --------------------------------------------MVKIAFIWAEDEAGWIGKDNDMPWHLSADLKHFKHLTSGHPVIMGKNTYLSLGRPLPKRTNIVVTRQTTPIEGVTLVNALTDLLANYGEDEEVFIIGGAHLFASTMSLATVLYRTVVEGDHHGDVKMAPIDYRTWQKV-AERHLQATESDPACTFEKW---
ZP_03487511.1 hypothetical protein EUBIF ---------------------------------------------MKLTLIAAIGKNRELGKNNDMIWHLPQDLKFFRQETSGHTIVMGRKTFESLPGKLPKRHHVVISRTKDLGEDIEMCESVEEFMKRYKDDEEIYCIGGGMIYSEMLKYASRLVLTQIDADADAEVYFPEFDESLYNK---KILSNIEENGVFYQHVEYTLK
ZP_02430941.1 hypothetical protein CLOSC -----------------------------------------TGGNSRMNLIVAVDKNWAIGNGNKLLVSIPQDMKFFRETTKGKVVAMGRKTLESFPQPLKNRVNVVLTTDQNYKNGAVIVHTIEQMLAELKKYEDIFVIGGESIYRQLLPYCSKAYVTRIDHAYDADTHFPDLDVDQWEMT--KISDEQTYFDLEYVFTIYER-
ZP_00999790.1 Dihydrofolate reductase [O ----------------------------------------------MITLVVARDRNGAIGKDGGIPWHLPGDLKMFQRETTGGALIMGRHTWESLPKPLNRRLNIVVTSRPDTAK--LICETVGEAVRLAEAEGRIYGIGGAGIYRDMLPLADRLLVTEVETAVEADTFFPEFDEEEWQETTR----ATAAGDPGYAVRELIRK
C2E963 Dihydrofolate reductase - ----------------------------------------MTGGTEMLAYIWAEDSAHHIGINGRLPWHLPNDLAYFKRQTSGHPMIMGKKTFDSFPKLLPGRLHVILTHSIEFEDQVVVVHNENDLRKWLEEHDSTFVIGGASLFKMFKDDVDLLYVTKIKEKFDADTTMPDLDMDRFALKYEEKGTTDEKNQYQHTFFVYERK
B8BKI9 Putative uncharacterized p ---------------------------------TLSNDVSQNGPQRNYQVVVAATRDMGIGKDGVLPWKLLGDLKFFKELTKKNAVIMGRKTWESLPRPLPGRLNIILTRSGSFEENVVICGSMNSALELLSSTPKVFVIGGGQVLRESLPSCEAVHLTDIQSSIECDTFIPPIDLSVFQPWYSSLPVV--ESNIRHSFVTYVR-
NP_001067911.1 Os11g0484400 [Oryza sativa ---------------------------------TLSNGVSQNGPQRNYQVVVAATRDMGIGKDGVLPWKLLGDLKFFKELTKKNAVIMGRKTWESLPRPLPGRLNIILTRSGSFEENVVICGSMNSALELLSSTPKVFVIGGGQVLRESLPSCEAVHLTDIQSSIECDTFIPPIDLSVFQPWYSSLPVV--ESNIRHSFVTYVR-
Pairwise Alignments
C2B0F4 Putative uncharacterized protein - Citrobacter youngae ATCC 29220 Length: 205. Score: 673. Identity: 100%. E-value: 1E-68. Query: 1 MLGVHLEVADSPAEQKIFLHIFLWLVDERLRFPYSGDNFFVSGKHSMISLIAALAVDRVIGMENAMPWNLPADLAWFKRNTLNKPVVMGRHTWESIGRPLPGRKNIVISSKPGTDDRVQWVKSVDEAIAACGDEPEIMVIGGGRVYEQFLPKAQKLYLTHIDAEVEGDTHFPDYEPDDWESVFSEFHDADAQNSHSYCFEILERR Sbjct: 1 MLGVHLEVADSPAEQKIFLHIFLWLVDERLRFPYSGDNFFVSGKHSMISLIAALAVDRVIGMENAMPWNLPADLAWFKRNTLNKPVVMGRHTWESIGRPLPGRKNIVISSKPGTDDRVQWVKSVDEAIAACGDEPEIMVIGGGRVYEQFLPKAQKLYLTHIDAEVEGDTHFPDYEPDDWESVFSEFHDADAQNSHSYCFEILERR YP_001125779.1 dihydrofolate reductase [Geobacillus thermodenitrificans NG80-2] Length: 189. Score: 514. Identity: 38%. E-value: 3E-50. Query: 41 VSGKHSMISLIAALAVDRVIGMENAMPWNLPADLAWFKRNTLNKPVVMGRHTWESIGRPLPGRKNIVISSKPGT-DDRVQWVKSVDEAIA-ACGDEPEIMVIGGGRVYEQFLPKAQKLYLTHIDAEVEGDTHFPDYEPDDWESVFSEFHDADAQNSHSYCFEILERR Sbjct: 23 CKGEKTMISHIVAMDENRVIGKDNQLPWHLPADLAYFKRVTMGHAIVMGRKTFEAIGRPLPGRDNVVVTRNPQFRPEGCLVLHSLEEVKQWIAARGEEVFIIGGAELFKATMPIADRLYVTNIFASFPGDTFYPPISEKEWKVVSYTPGVKDEKNPYEHAFLIYERK ZP_01201001.1 dihydrofolate reductase [Flavobacteria bacterium BBFL7] Length: 241. Score: 508. Identity: 29%. E-value: 1E-49. Query: 27 DERLRFPYSGDNFFVSGKHSMISLIAALAVDRVIGMENAMPWNLPADLAWFKRNTLNKPVVMGRHTWESIGRPLPGRKNIVISSKPGTD-DRVQWVKSVDEAIAACGDEPEIMVIGGGRVYEQFLPKAQKLYLTHIDAEVEGDTHFPDYEPDDWESVFSEFHDADAQNSHSYCFEILER Sbjct: 62 TKSNPLPETKIINTPVSKKRVITMIAAAGANNELGKDGDLVWHLPDDFKRFKSLTTGHHIIMGRKTFESFPKPLPNRTHIILTRDANYKTDGGIVVHDLSTALAAASSDEEPFIIGGGEIYKLGLEIADRIELTRVHGSFDVDTYFPEFDEKQWKLIRTEHHPADDKHEYAFDFETWER ZP_02180882.1 dihydrofolate reductase [Flavobacteriales bacterium ALC-1] Length: 310. Score: 496. Identity: 32%. E-value: 3E-48. Query: 47 MISLIAALAVDRVIGMENAMPWNLPADLAWFKRNTLNKPVVMGRHTWESIGRPLPGRKNIVISSKPGT--DDRVQWVKSVDEAIAACGDEPEIMVIGGGRVYEQFLPKAQKLYLTHIDAEVE-GDTHFPDYEPDDWESVFSEFHDADAQNSHSYCFEILERR Sbjct: 149 ELTIIVAAGEKNAIGKDNDLIWHLSDDLKRFKKLTNGHHIIMGRKTFESFPKPLPNRIHIVITRQSDYNVPDGVIVVNSLEDALDAARKDNQPFIIGGGEIYKQSINRVDKLEITRVHSTFEDADTFFPKIDTSIWREVSRTTHDADEKHAHAFSFITYLKK YP_747242.1 dihydrofolate reductase [Nitrosomonas eutropha C91] Length: 176. Score: 494. Identity: 40%. E-value: 6E-48. Query: 41 VSGKHSMISLIAALAVDRVIGMENAMPWNLPADLAWFKRNTLNKPVVMGRHTWESIGRPLPGRKNIVISSKPGTD-DRVQWVKSVDEAIAA-CGDEPEIMVIGGGRVYEQFLPKAQKLYLTHIDAEVEGDTHFPDYEPDDWESVFSEFHDADAQNSHSYCFEILERR Sbjct: 4 LQPATSRLAILAAISANRVIGLNNSLPWHLPADLKHFKQLTTGHIVVMGRRTFDSIGKPLPDRTNVVLSRQHVLDVPGIITAHSIQEVLDHFANDDRQIFVIGGAELYRQTLPLCQRLYLTEIQEDFEGDTFFPEYDHDDWQEISREIHHETGGSGLEYHFVMLDHK YP_001023231.1 dihydrofolate reductase [Methylibium petroleiphilum PM1] Length: 259. Score: 490. Identity: 40%. E-value: 2E-47. Query: 46 SMISLIAALAVDRVIGMENAMPWNLPADLAWFKRNTLNKPVVMGRHTWESIG---RPLPGRKNIVISSKPGT--DDRVQWVKSVDEAIAACGDEPEIMVIGGGRVYEQFLPKAQKLYLTHIDAEVEGDTHFPDYEPDDWESVFSEFHDADAQNSHSYCFEILERR Sbjct: 1 MDLAIIAACARNGVIGRNNDLPWRLPEDLAHFRSTTGGWPVIMGRLTWESLPARFRPLPGRRNIIVSRGGVRGVPKGVDVVASLEAALELVQAERRAFVIGGARLYEAALPLADELFLTEIDEDFEGDVYFPEFDRSAFVEHHRMRRQAEAPNTFTYSFAHYRRK ZP_02478257.1 dihydrofolate reductase [Haemophilus parasuis 29755] Length: 192. Score: 486. Identity: 44%. E-value: 4E-47. Query: 43 GKHSMISLIAALAVDRVIGMENAMPWNLPADLAWFKRNTLNKPVVMGRHTWESIGRPLPGRKNIVISSKPGTDDRVQWVKSVDEAIAACG---DEPEIMVIGGGRVYEQFLPKAQKLYLTHIDAEVEGDTHFPDYEPDDWESVFSEFHDADAQNSHSYCFEILER Sbjct: 25 GNRMKISVIVARTLNKVIGKDNAMPWHLPVDLAWFRENTLGKPVIMGRKTYESIGRLLPKRPNIILSRSGFAIDGAYSAISLEQAVELAKNFANSDEIMIIGGGELFKQTMPFADKLYLTEIQANIEGDTFF-EFDETQWQQIAEKWSEIDEQNSYRCRFMILDK YP_128633.1 putative dihydrofolate reductase [Photobacterium profundum SS9] Length: 220. Score: 485. Identity: 54%. E-value: 6E-47. Query: 40 FVSGKHSMISLIAALAVDRVIGMENAMPWNLPADLAWFKRNTLNKPVVMGRHTWESIGRPLPGRKNIVISSKPGTD-DRVQWVKSVDEAIAACGDEPEIMVIGGGRVYEQFLPKAQKLYLTHIDAEVEGDTHFPDYEPDDWESVFSEFHDADAQNSHSYCFEILER Sbjct: 51 YLRRYEVKISMIAAMAKDRVIGKDNAMPWHLPADFAWFKKSTLGKPIVMGRKTFESIGRPLPGRLNIVISRNPEFSVEGVTVVADIEAAKHAAGDIGELMVIGGGSIYEACLPSADRLYLTFIDLDVDGDTCFPDWGEG-WIKSYTEHYSADEKNAHDMQFVILER ZP_02160204.1 dihydrofolate reductase type I; trimethoprim resistance [Kordia algicida OT-1] Length: 310. Score: 485. Identity: 36%. E-value: 6E-47. Query: 48 ISLIAALAVDRVIGMENAMPWNLPADLAWFKRNTLNKPVVMGRHTWESIGRPLPGRKNIVISSKPGT--DDRVQWVKSVDEAIAACG-DEPEIMVIGGGRVYEQFLPKAQKLYLTHIDAEVEGDTHFPDYEPDDWESVFSEFHDADAQNSHSYCFEILER Sbjct: 150 LVIIVAAAENNVIGKDNQLIWHLSDDLKRFKKLTSGHHIIMGRKTFESFPKPLPNRTHIVITRQKDYKAPKGVIVVHTMKEAVSVATLSDAEPYVIGGGEIYKQALPFATKIELTRVHHEFEGDAYFPEIDKKDWKETNNVFHTKDDKHEYEFSFLTYER YP_442211.1 dihydrofolate reductase [Burkholderia thailandensis E264] Length: 219. Score: 480. Identity: 42%. E-value: 2E-46. Query: 55 AVDRVIGMENAMPWNLPADLAWFKRNTLNKPVVMGRHTWESIGRPLPGRKNIVISSKPGTD-DRVQWVKSVDEAIAACGDEP--EIMVIGGGRVYEQFLPKAQKLYLTHIDAEVEGDTHFPDYEPDDWESVFSEFHDADAQNSHSYCFEILERR Sbjct: 63 ARNGVIGRDNRLPWKLPEDLAFFKRTTMGAPIVMGRKTHESIGRPLPGRRNIVVTRDAARRFDGCDTATSLGDALALAERDGAAEAFLIGGAQLYAEGLRHADKLIVTEIDQDFEGDASFPAPDPAQWEAVSRDAHRAAPPNDFAYAFVVYRRK YP_574617.1 dihydrofolate reductase [Chromohalobacter salexigens DSM 3043] Length: 195. Score: 478. Identity: 40%. E-value: 4E-46. Query: 48 ISLIAALAVDRVIGMENAMPWNLPADLAWFKRNTLNKPVVMGRHTWESIGRPLPGRKNIVISSKPGT---DDRVQWVKSVDEAIAACGDE------PEIMVIGGGRVYEQFLPKAQKLYLTHIDAEVEGDTHFPDYEPDDWESVFSEFHDADAQNSHSYCFEILERR Sbjct: 19 IALVAAMSRNRVIGVDNKLPWHLPEDLKFFKAVTMSKPLVMGRKTFESIGRPLPGRLNIVVTRDRGYAQDHDGIRVCHDLASALDMADGQAIIDGVEDICVIGGGEIFAEALPCATRLYLTEVDIEVEGDAWFPAFDAREWQETQRVP-GQGGEGKPEYAFVHYTRR NP_296351.1 dihydrofolate reductase [Deinococcus radiodurans R1] Length: 180. Score: 477. Identity: 39%. E-value: 6E-46. Query: 48 ISLIAALAVDRVIGMENAMPWNLPADLAWFKRNTLNKPVVMGRHTWESIGR-PLPGRKNIVISSKPGTD-DRVQWVKSVDEAIAACGDEPEIMVIGGGRVYEQFLPKAQKLYLTHIDAEVEGDTHFPDYEPDDWESVFSEFHDADAQNSHSYCFEILERR Sbjct: 17 IVAIAAQTENRVIGRDGGMPWHLPADFAHFRALSVGKPNIMGRKVFDTLRRKPLPERVNIVLTRNENLKFDGCLIAHSPEEALQLAGDAPEIAIIGGEEIYRLYWDRLTRLEMTLIHAELDGDTFFPEIGP-EWELAQETFRPADEKNRYDLTFQTWRRR Q39687 Dihydrofolate reductase-thymidylate synthetase - Daucus carota Length: 577. Score: 475. Identity: 29%. E-value: 8E-46. Query: 24 WLVDERLRFPYSGDNFFVSGKHSMISLIAALAVDRVIGMENAMPWNLPADLAWFKRNTL-------NKPVVMGRHTWESIG---RPLPGRKNIVISSKPGTD----DRVQWVKSVDEAIAACGDEP------EIMVIGGGRVYEQFL--PKAQKLYLTHIDAEVEGDTHFPDYEPDDWESVFSEFHDADAQNSHSYCFEILER Sbjct: 49 YMASERLANPTNGSGITRPDPQRTYQVVVAATQNMGIGKDGKLPWRLPSDMKFFKDVTMTTSDPLKRNAVIMGRKTWESIPIQHRPLPGRLNVVLTRSGSFDIATVENVVICGSMISALELLAGSPYCVSVEKVFVIGGGQIYREALNAPGCDAVHITEIEEHIECDTFIPLLDESVFQPWYSSFPLV--ENKIRYCFTTYVR ZP_05671924.1 dihydrofolate reductase [Enterococcus faecium 1,231,408] Length: 175. Score: 475. Identity: 35%. E-value: 9E-46. Query: 47 MISLIAALAVDRVIGMENAMPWNLPADLAWFKRNTLNKPVVMGRHTWESIG-RPLPGRKNIVISSKPGTD-DRVQWVKSVDEAIAACGDEPEIMVI-GGGRVYEQFLPKAQKLYLTHIDAEVEGDTHFPDYEPDDWESVFSEFHDADAQNSHSYCFEILER Sbjct: 1 MLAAIWAQDENGLIGKEDRLPWRLPNDLKFFKQMTEANTLVMGRKTFEGMGSRPLPNRQTIVLTRDSSYKAEGVHVMHSVEDVLALEKETDGIFFIAGGSAVYQEFLPFCTILYRTVIHHVFDGDAYFPPVDWSDWSLINTSQGEMDEKNRYPHQFETYQR YP_001101808.1 dihydrofolate reductase [Yersinia ruckeri] Length: 191. Score: 475. Identity: 44%. E-value: 1E-45. Query: 48 ISLIAALAVDRVIGMENAMPWNLPADLAWFKRNTLNKPVVMGRHTWESIGRPLPGRKNIVISSKPGTD--DRVQWVKSVDEAIAACGDEP---EIMVIGGGRVYEQFLPKAQKLYLTHIDAEVEGDTHFPDYEPDDWESVFSEFHDADAQNSHSYCFEILERR Sbjct: 28 ISLILAMADNGTIGDKNALPWHLPNDLQFLKKSTMGKPIVMGRKTYQSIGRPLPGRTNVVISRSLEKEALPGCLIYSDLSVAIAALKKEPEVEEIMIMGGAQIYRAALPMMDRLYLTHVHANIEGDTQMPPFDFSHATLIFEEKHFKDEKNRYDYTFEIWDFK YP_001580403.1 dihydrofolate reductase [Burkholderia multivorans ATCC 17616] Length: 209. Score: 473. Identity: 37%. E-value: 1E-45. Query: 13 AEQKIFLHIFLWLVDERLRFPYSGDNFFVSGKHSMISLIAALAVDRVIGMENAMPWNLPADLAWFKRNTLNKPVVMGRHTWESIGRPLPGRKNIVISSKPGTD-DRVQWVKSVDEAIAACGDEP--EIMVIGGGRVYEQFLPKAQKLYLTHIDAEVEGDTHFPDYEPDDWESVFSEFHDADAQNSHSYCFEILERR Sbjct: 16 ARRRSTPRGGAPVPVESAPFRFFLSPTFMTT----LTLIVARARNGIIGRDNQLPWKLPEDLAFFKRTTMGAPIVMGRKTHESIGRPLPGRRNIVVTRDASRRFDGCDTVTSLADALALAARDGAAEAFLIGGAQLYAEGLAQADKLIVTEIDADFEGDASFPAPDPAQWQEVSRDAHQAATPNTFGYAFVVYARK ZP_02906323.1 Dihydrofolate reductase [Burkholderia ambifaria MEX-5] Length: 215. Score: 473. Identity: 40%. E-value: 2E-45. Query: 28 ERLRFPYSGDNFFVSGKHSMISLIAALAVDRVIGMENAMPWNLPADLAWFKRNTLNKPVVMGRHTWESIGRPLPGRKNIVISSKPGTD-DRVQWVKSVDEAIAACGDEP--EIMVIGGGRVYEQFLPKAQKLYLTHIDAEVEGDTHFPDYEPDDWESVFSEFHDADAQNSHSYCFEILERR Sbjct: 37 ESAPFRFSSSPIFMTT----LTLIVARARNGIIGRDNQLPWKLPEDLAFFKRTTMGAPIVMGRKTHESIGRPLPGRRNIVVTRDAARRFDGCDTVTSLADALALAARDGAAEAFLIGGAQLYAEGRALADKLIVTEIDADFDGDASFPAPDPAHWHEVSREPHQAAAPNTFGYAFVVYARK YP_810587.1 dihydrofolate reductase [Oenococcus oeni PSU-1] Length: 170. Score: 473. Identity: 38%. E-value: 2E-45. Query: 47 MISLIAALAVDRVIGMENAMPWNLPADLAWFKRNTLNKPVVMGRHTWESIG-RPLPGRKNIVISSKPGT---DDRVQWVKSVDEAIAACGDEP-EIMVIGGGRVYEQFLPKAQKLYLTHIDAEVEGDTHFPDYEPDDWESVFSEFHDADAQNSHSYCFEILERR Sbjct: 1 MITSIWAQSKNNVIGRNNHLPWSLPDDLKFFRQETKNKAVVMGRKTYESFGSKALPKRLNIILTSNMDFKSNDPEVKIVHSPIEAVNTAKEQHLPLYVIGGASVYESFMNMADRLLITLVDANIKGDTFAPNFSEKSFSLVSQCHHAQDKKHAYSFDFLTYERK YP_001174482.1 dihydrofolate reductase [Pseudomonas stutzeri A1501] Length: 246. Score: 468. Identity: 42%. E-value: 7E-45. Query: 40 FVSGKHSMISLIAALAVDRVIGMENAMPWNLPADLAWFKRNTLNKPVVMGRHTWESIGRPLPGRKNIVISSKPGTD-DRVQWVKSVDEAIAACGDE------PEIMVIGGGRVYEQFLPKAQKLYLTHIDAEVEGDTHFPDYEPDDWESVFSEFHDADAQNSHSYCFEILERR Sbjct: 75 AMNQTRLPLAMIAALAERHVIGRDNIMPWHLPADLRHFKAMTLGKPIIMGRKTWDSLGRPLPGRLNLVVSRQADLQLDGAETFTDLDAALVRAEQWAREQGVDELMLIGGAQLYAQALGQAQRLYLTRIDAQPEGDAFFPVFDEHEWQCIDSQPHPAEGE-APAYRFETWQRR YP_001599935.1 dihydrofolate reductase [Neisseria meningitidis 053442] Length: 196. Score: 465. Identity: 37%. E-value: 1E-44. Query: 37 DNFFVSGKHSMISLIAALAVDRVIGMENAMPWNLPADLAWFKRNTLNKPVVMGRHTWESIG-RPLPGRKNIVISSKPGT-DDRVQWVKSVDEAIAACGDEPEIMVIGGGRVYEQFLPKAQKLYLTHIDAEVEGDTHFPDYEPDDWESVFSEFHDADAQNSHSYCFEILER Sbjct: 27 RRHFCGGNMLKITLIAACAENLCIGAGNAMPWHIPEDFAFFKAYTLGKPVIMGRKTWESLPVKPLPGRRNIVISRQADYCAAGAETAASLEAALALCAGAEEAVIMGGAQIYGQAMPLATDLRITEVDLSVEGDAFFPEIDRTHWKEAGRTERRVSSK-GTRYAFVHYLR YP_003089177.1 Dihydrofolate reductase [Dyadobacter fermentans DSM 18053] Length: 183. Score: 465. Identity: 37%. E-value: 1E-44. Query: 44 KHSMISLIAALAVDRVIGMENAMPWNLPADLAWFKRNTLNKPVVMGRHTWESIGRPLPGRKNIVISSKPGTD-DRVQWVKSVDEAIAACGDEP--EIMVIGGGRVYEQFLPKAQKLYLTHIDAEVEGDTHFPDYEPDDWESVFSEFHDADAQNSHSYCFEILERR Sbjct: 16 TQMKISIIVAAAENGAIGRDNQLLWRLSDDLKRFKQLTLGHPMIMGRKTFESIGKPLPGRTSIVITRNANFAFDGVVVVHSLDEALEKAKEIDSQEVCIVGGGEIYEQSQAIATHIYLTKVHTSVVGDTFFSIREPEAWTETERISHEPDERHIFPFEFINYIKK ZP_01863662.1 phosphoribosylaminoimidazole carboxylase ATPase subunit [Erythrobacter sp. SD-21] Length: 528. Score: 466. Identity: 35%. E-value: 1E-44. Query: 28 ERLRFPYSGDNFFVSGKHSMISLIAALAVDRVIGMENAMPWNLPADLAWFKRNTLNKPVVMGRHTWESIGRPLPGRKNIVISSKPGTD-DRVQWVKSVDEAIAACGDEPEIMVIGGGRVYEQFLPKAQKLYLTHIDAEVEGDTHFPDYEPDDWESVFSEFHDADAQNSHSYCFEILER Sbjct: 347 ERGPQDGPHHPDLPRHPRMSLFLIYARAANGAIGKQGRLPWHLPADLKRFKALTMGKPMIMGRKTFESLPGLLPGRRHIVLTRKERWDSTGAEVVRSVGEAVAKA-GEGDIAVIGGAAIFDVFMPLAKKVELTEIHRDFDGDVFMPPLGP-EWDLAGTEDFEADGDT-PAYSFHTYRR ZP_04983084.1 dihydrofolate reductase type I [Francisella tularensis subsp. holarctica 257] Length: 180. Score: 446. Identity: 34%. E-value: 2E-42. Query: 30 LRFPYSGDNFFVSGKHSMISLIAALAVDRVIGMENAMPWNLPADLAWFKRNTLNKPVVMGRHTWESIGRPLPGRKNIVISSKPGTDDR-VQWVKSVDEAIAACGDEP--EIMVIGGGRVYEQFLPKAQKLYLTHIDAEV-EGDTHFPDYEPDDWESVFSEFHDADAQNSHSYCFEILER Sbjct: 2 LKYIKMTKNRFLK----MISLIVAYDKNFGIGKENTLAWKLSEDLKNFKKITENNYIVMGRKTFESIGRPLPNRKNIILTRNKDYKQDKCLIINSTQDILNFAESKPHYEIFIIGGAQIYKEFLKYADRLYITEVDAEMTDLDAFFPQWDKSKYKRIGHKQFKKNDKNEFDFTFSIFEK B9H4E7 Dihydrofolate reductase-thymidylate synthase - Populus trichocarpa Length: 283. Score: 446. Identity: 27%. E-value: 2E-42. Query: 44 KHSMISLIAALAVDRVIGMENAMPWNLPADLAWFKRNT-------LNKPVVMGRHTWESIG---RPLPGRKNIVISSK--PGTDDRVQWVKSVDEAIAACGDEP------EIMVIGGGRVYEQFL--PKAQKLYLTHIDAEVEGDTHFPDYEPDDWESVFSEFHDADAQNSHSYCFEIL Sbjct: 51 PMRSYQVVVAATRDMGIGKDGKLPWRLPSDLKFFKEVTLATSDPGKQNAILMGRKTWESIPIKYRPLPDRLNVVLTRSFEIEDEENVITCGSISSALELLAETPYCFSIDKVFVIGGGQILRETLNGPGCDAIHVTEIESSVECDTFIPSIDFSKFQPWYSSPPLV--ENGFRYSFVTY B9H4E4 Dihydrofolate reductase-thymidylate synthase - Populus trichocarpa Length: 252. Score: 445. Identity: 27%. E-value: 3E-42. Query: 32 FPYSGDNFFVSG--KHSMISLIAALAVDRVIGMENAMPWNLPADLAWFKRNT-------LNKPVVMGRHTWESIG---RPLPGRKNIVISSK--PGTDDRVQWVKSVDEAIAACGDEP------EIMVIGGGRVYEQFL--PKAQKLYLTHIDAEVEGDTHFPDYEPDDWESVFSEFHDADAQNSHSYCFEIL Sbjct: 2 QPWFRRFTAIAGEIPMRSYQVVVAATRDMGIGKDGKLPWRLPCDLKFFKEITLATSDPGKQNAILMGRKTWESIPIKYRPLPGRLNVVLTRSFEIEDEENVITCGSISSALELLAEAPYCFSIDKVFVIGGGQILRETLNGPGCDAIHVTEIETSVECDTFIPSIDFSKFQPWYSSPPLV--ENGIRYSFVTY C1YEX4 Dihydrofolate reductase - Nakamurella multipartita DSM 44233 Length: 312. Score: 441. Identity: 41%. E-value: 8E-42. Query: 46 SMISLIAALAVDRVIGMENAMPWNLPADLAWFKRNTLNKPVVMGRHTWESIGRPLPGRKNIVISSKPGTD-DRVQWVKSVDEAIAA-CGDEPEIMVIGGGRVYEQFLPKAQKLYLTHIDAEVEGDTHFPDYEPDDWESVFSEFHDADAQNSHSYCFEILERR Sbjct: 26 PTVVLVAAVARNGVIGAAGTMPWHIPADLKRFKRLTMGHPMVMGRKTFESMG-LLPGRRSIVITRDPHWRAPGAEVADSLDRAIALGAQTDPVVMVVGGGEIYAQALPRADRLEITHLDLSAPGDTVFPAIDPALWAVTDREEAD-------GYAFVTYRRR YP_002566814.1 dihydrofolate reductase region [Halorubrum lacusprofundi ATCC 49239] Length: 194. Score: 437. Identity: 36%. E-value: 2E-41. Query: 48 ISLIAALAVDRVIGMENAMPWNLPADLAWFKRNTLNKPVVMGRHTWES----IGRPLPGRKNIVI-SSKPGTDDRVQWVKSVDEAIAAC------GDEPEIMVIGGGRVYEQFLPKAQKLYLTHIDAEVEGDTHFPDYEPDDWESVFSEFHDADAQNSHS---YCFEILER Sbjct: 21 LVLVAAVAENRVIGDDGGMPWHYPADLARFKRLTTGHPVIVGRATYESIADRIGGPLPDRTSVVLTTRDLDLPEGAVVANDLDEAVDLAGADAADRGVDDVYVIGGATVYEQFLDRADRMVLTEVPEQPDGDTRFPDWDDEEWVETEREVVGADGERGGEADALAFVTYER YP_001832848.1 dihydrofolate reductase [Beijerinckia indica subsp. indica ATCC 9039] Length: 198. Score: 437. Identity: 33%. E-value: 3E-41. Query: 21 IFLWLVDERLRFPYSGDNFFVSGKHSMISLIAALAVDRVIGMENAMPWNLPADLAWFKRNTLNKPVVMGRHTWESIGRPLPGRKNIVISSKPGT-DDRVQWVKSVDEAIAACGDEPEIM------VIGGGRVYEQFLPKAQKLYLTHIDAEVEGDTHFPDYEPDDWESVFSEFHDADAQNSHSYCFEILERR Sbjct: 4 LFLRSLPNHKLDPALGDNDFP------LTIVAALADNRVIGLNQAMPWDLPGDRRHFRERTWGKPMLMGRKTFESIGRALPGRETIVLTRDETFAAPGVLVAHDLEGALGLAHDWARIMGAKTIILVGGGELFAALLPRVERLELTLVEGNPKGDTFFPPIDWSQWEEEKRSGPLQGPNDTISYQFVDYHRK YP_804567.1 dihydrofolate reductase [Pediococcus pentosaceus ATCC 25745] Length: 161. Score: 434. Identity: 34%. E-value: 5E-41. Query: 47 MISLIAALAVDRVIGMENAMPWNLPADLAWFKRNTLNKPVVMGRHTWESIGRPLPGRKNIVISSKPGTDDRVQW-VKSVDE--AIAACGDEPEIMVIGGGRVYEQFLPKAQKLYLTHIDAEVEGDTHFPDYEPDDWESVFSEFHDADAQNSHSYCFEILER Sbjct: 1 MISMIWAEDLRHGIGKQQSIPWHIPGDMAFFKKTTSGNTVVMGRKTFDSIGKALPNRKNIVLSHHPTSLPDSVVGVGSLSELQAIFETHPNEKFYIIGGSHLYNALLSQADELLITRIQKDYQCEVLAPDITQNEFKLASSVEHESTERN-PAYTFETWIR ZP_02432762.1 hypothetical protein CLOSCI_03017 [Clostridium scindens ATCC 35704] Length: 174. Score: 434. Identity: 34%. E-value: 6E-41. Query: 45 HSMISLIAALAVDRVIGMENAMPWNLPADLAWFKRNTLNKPVVMGRHTWESIGRPLPGRKNIVISSKPGTD-DRVQWVKSVDEAIAACGDEPEIMVIGGGRVYEQFLPKAQKLYLTHIDAEVE-GDTHFPDYEPDDWESVFSEFHDADAQNSHSYCFEILERR Sbjct: 1 MTMIGLIVARSKNNVIGKNGKIPWKIKGEQKQFRELTTNKTVIMGRKSYNEIGHPLANRLNIIVSNTANYTGENLITVHSLNEAIQVA-GNKDIFVIGGYSLYKEALPIVDKMYITEIDIEVSNGDVFFPQFNIDNFELSIGETFG----NDIKYTRTLYTRK YP_818239.1 dihydrofolate reductase [Leuconostoc mesenteroides subsp. mesenteroides ATCC 8293] Length: 165. Score: 429. Identity: 31%. E-value: 2E-40. Query: 45 HSMISLIAALAVDRVIGMENAMPWNLPADLAWFKRNTLNKPVVMGRHTWESIGRPLPGRKNIVISSKPGTD---DRVQWVKSVDEAIAA-CGDEPEIMVIGGGRVYEQFLPKAQKLYLTHIDAEVEGDTHFPDYEPDDWESVFSEFHDADAQNSHSYCFEILER Sbjct: 1 MTKIKMVWAEDRQHAIGKDGGIPWHMPDDLKLFRDETVNTLMIMGRPTWLSIGRPLPKRTTVVMTRQEDWTPSYPEVKVIHSIEEAKNLIAKEERDITIAGGAAVYREFMPYATDLVITRVDGVIDGDTFVDEVDLTQFQLKSSEPHAKDDNHDYAFVVERYER B9R7Y4 Bifunctional dihydrofolate reductase-thymidylate synthase, putative - Ricinus communis Length: 591. Score: 427. Identity: 27%. E-value: 3E-40. Query: 34 YSGDNFFVSGKHSMISLIAALAVDRVIGMENAMPWNLPADLAWFKRNT-------LNKPVVMGRHTWESIG---RPLPGRKNIVISSKP----GTDDRVQWVKSVDEAIAACGDEP------EIMVIGGGRVYEQFL--PKAQKLYLTHIDAEVEGDTHFPDYEPDDWESVFSEFHDADAQNSHSYCFEILER Sbjct: 73 PRGNANMHLDRNRRYQVVVAATRDMGIGKDGKLPWRLPSDLKFFKELTLTTSSPGKRNAVVMGRKTWESIPLKYRPLPGRLNIVLTCSGGCDITTAEDVLTCGSIPSALELLAEAPYSFLIEKVFFIGGGQILRKTINAPGCDAIHITEIETSIECDTFIPVIDFSLFHPWYSSLPIV--ENNVRYSFATYVR ZP_04564410.1 dihydrofolate reductase [Mollicutes bacterium D7] Length: 156. Score: 425. Identity: 37%. E-value: 6E-40. Query: 47 MISLIAALAVDRVIGME---NAMPWNLPADLAWFKRNTLNKPVVMGRHTWESIGRPLPGRKNIVISSKPGTDDRVQWVKSVDEAIAACGDEPE-IMVIGGGRVYEQFLPKAQKLYLTHIDAEVEGDTHFPDYEPDDWESVFSEFHDADAQNSHSYCFEILER Sbjct: 1 MINIIVATDEDLLIGKKDSRNGMPWNVPEDLQHFKATTLNKTILMGLTTYQAIGRPLPNRKTIVVSFEPFEDERVEVRSSLEEVIEEYRSSGEDLFISGGASIYKQCLPIADQLLISRIPGKHEGETYFPNFDEYGYKLVAQKPFET-------FTLETYKR YP_001598129.1 Tri [Salmonella enterica subsp. enterica serovar Choleraesuis] Length: 177. Score: 425. Identity: 33%. E-value: 6E-40. Query: 41 VSGKHSMISLIAALAVDRVIGMENAMPWNLPADLAWFKRNTLNKPVVMGRHTWESIGRPLPGRKNIVISSKPGTD-DRVQWVKSVDEAIAACGD-EPEIMVIGGGRVYEQFLPKAQKLYLTHIDAEVEGDTHFPDYEPDDWESVFSEFHDADAQNSHSYCFEILER Sbjct: 1 MNSESVRIYLVAAMGANRVIGNGPNIPWKIPGEQKIFRRLTEGKVVVMGRKTFESIGKPLPNRHTLVISRQANYRATGCVVVSTLSHAIALASELGNELYVAGGAEIYTLALPHAHGVFLSEVHQTFEGDAFFPMLNETEFELVSTETIQAV----IPYTHSVYAR C2MBL2 Dihydrofolate reductase - Porphyromonas uenonis 60-3 Length: 173. Score: 424. Identity: 36%. E-value: 7E-40. Query: 46 SMISLIAALAVDRVIGMENAMPWNLPADLAWFKRNTLNKPVVMGRHTWESIG-RPLPGRKNIVISSK--PGTDDRVQWVKSVDEAIAAC--GDEPEIMVIGGGRVYEQFLPKAQKLYLTHIDAEV-EGDTHFPDYEPDDWESVFSEFHDADAQNSHSYCFEILER Sbjct: 1 MEIWIIVATARDRAIGRDGTMPWRLKDDLRRLKATTTGHAVIMGRHTWDSIGARPLPNRYNIVVSRTLPEGDAETHYVASTLEQALQHCQQAGYDRVYIMGGGVLYKSGLPYATHLNLTMVDTVVPDADTHFPEINLSEWSKLEEAHYPADERNDYPVTQTLYKR C1X560 Dihydrofolate reductase - Kytococcus sedentarius DSM 20547 Length: 337. Score: 424. Identity: 29%. E-value: 7E-40. Query: 37 DNFFVSGKHSMISLIAALAVDRVIGMENAMPWNLPADLAWFKRNTLNKPVVMGRHTWESIGRPLPGRKNIVISSKPGTDDR----------------VQWVKSVDEAIAACGDEPEIMVIGGGRVYEQFLPKAQKLYLTHIDAEV-EGDTHFP---DYEPDDWESVFSEFHDADAQNSHSYCFEILER Sbjct: 157 PAVMTRGFSQSLTLVVAVARNGAIGRDGDLPWHLPGDLKHFKDTTMGGTMVMGRRTFESFPRPLPGRRHVVMTSDPTWLPGGPAVEGDPASGARFDEVLVARSWAEAL-LMAGDGEVFVVGGAGVFADALPVADRLVLTEVDQSPQDADTFFPITWPVDPTVWHESSRTP-------GEGYAIVEYRR YP_002139599.1 dihydrofolate reductase region [Geobacter bemidjiensis Bem] Length: 306. Score: 423. Identity: 38%. E-value: 1E-39. Query: 46 SMISLIAALAVDRVIGMENAMPWNLPADLAWFKRNTLNKPVVMGRHTWESIGRPLPGRKNIVISSKPGTDDRVQWVKSVDEAIAACGDEPEIMVIGGGRVYEQFLPKAQKLYLTHIDAEVEGDTHFPDYEPDDWESVFSEFHDADAQNSHSYCFEILER Sbjct: 1 MIISTIAALSDNRVIGADGGLPWDIPSDLTRFRSITMGHTVIMGRKTYESIGHPLLGRRNIVLTRKGSQIEGCEIARNVPAAIAAAEGEEEVFICGGGEVFQEALPLCQRLYLTVVHGNYRGDAFLPELPEGFVELHREEFPDTTPPS----SFVVLEK YP_832498.1 dihydrofolate reductase [Arthrobacter sp. FB24] Length: 194. Score: 421. Identity: 34%. E-value: 2E-39. Query: 48 ISLIAALAVDRVIGMENAMPWNLPADLAWFKRNTLNKPVVMGRHTWESIG---RPLPGRKNIVISSKPGTDD-----RVQWVKSVDEAI---AACGDEPEIMVIGGGRVYEQFLPKAQKLYLTHIDAEVEGDTHFPDYEPDDWESVFSEFHD--ADAQNSHSYCFEILER Sbjct: 23 VGLVWAQTTAGVIGKDGDMPWHLPEDMKHFTRLTTGHPVIMGRKTWLSFPDKYRPLPGRTNIVVTRQEGWGDTPDARGAIAVKSLDDALLESQFAPGHETVWVLGGGEIFAQTLDIADVAVVTFIDSETDGDTYAPELGY-EWKLAASEPATGWLTSATGTRYRFTMWRR C1W4R8 Dihydrofolate reductase - Jonesia denitrificans DSM 20603 Length: 191. Score: 419. Identity: 32%. E-value: 3E-39. Query: 43 GKHSMISLIAALAVDRVIGMENAMPWNLPADLAWFKRNTLNKPVVMGRHTWESIG-RPLPGRKNIVISSKPGTD-DRVQWVKSVDEAIAACG-----DEPEIMVIGGGRVYEQFLPKAQKLYLTHIDAEVEGDTHFPDYEPDDWESVFSEFHDADAQNSHSYCFEILER Sbjct: 6 AAKPQLSLIWAQSLNGVIGRSGTIPWHEPTDLAHFQKTTRGGVVIMGRHTWESLPVTPLPQRVNIVLTSDRDYRAPGARVVTTPQQALDLAHWYTQVGHQAIWVIGGRQVYDTFMDYATQLIVTTVGTVIEGDTEAPRIPP---HFVPQEPHQLATHSDYEVTVTTWLR NP_870608.1 dihydrofolate reductase [Rhodopirellula baltica SH 1] Length: 195. Score: 418. Identity: 35%. E-value: 4E-39. Query: 48 ISLIAALAVDRVIGMENAMPWNLPADLAWFKRNTLNKPVVMGRHTWESIGRPLPGRKNIVISSKPGTD-DRVQWVKSVDEAIAACGDEPEIMVIGGGRVYEQFLPKAQKLYLTHIDAEVEGDTHFPDYEPDDWESVFSEFHDADAQNSHSYCFEILERR Sbjct: 31 ITAVVAATPNGVIGDDQDMPWRLSSDLKRFKKATMGGALIMGRKTFESIGRVLPGRQTIVLTRQGHWQFPGTQTASGKSEAIALAAD-RRIFVVGGGQIYQQWFPLCTELWWTRVWANVSGDTRV-DLPLDEFELVSQTSFPVTAKDDYPTDWLRMRRR NP_492364.1 DiHydroFolate Reductase family member (dhfr-1) [Caenorhabditis elegans] Length: 189. Score: 418. Identity: 27%. E-value: 4E-39. Query: 45 HSMISLIAALAVDRVIGMENAMPWNLPADLAWFKRNTLN-------KPVVMGRHTWESIG---RPLPGRKNIVISSK--PGTDDRVQWVKSVDEAIAACGDEP------EIMVIGGGRVYEQFL--PKAQKLYLTHIDAEVEGDTHFPDYEPDDWE-----SVFSEFHDADAQNSHSYCFEILE Sbjct: 1 MRKMNLIVAMDAEGGIGKNGVLPWRIKKDMQYFASVTKNVSDQSKRNAVLMGRKCWESIPVTRRPLAGRLNIVLSRQLPAQKSDDYIVVNSLEAAMKLLSEPPFVDSIETIWNIGGAEIYDLALRENLVDEIHLTRIFKNFEADVHLKSLDFSKMEKVQNAEVSSENSEIFEENGLKFEFCKWK YP_877291.1 dihydrofolate reductase [Clostridium novyi NT] Length: 170. Score: 417. Identity: 34%. E-value: 5E-39. Query: 47 MISLIAALAVDRVIGMENAMPWNLPADLAWFKR--NTLNKPVVMGRHTWESIGRPLPGRKNIVISSKPGT---DDRVQWVKSVDEAIAACGDEPEIMVIGGGRVYEQFLPKAQKLYLTHIDAEVEGDTHFPDYEPDDWESVFSEFHDADAQNSHSYCFEILER Sbjct: 1 MLSIVVAIGKNNVIGKDHSLPWHLPNDLKYFKKVTLTESKTMIMGRKTFQSLKALLPGRKHIILTKNKNFNMKDSNVEIINKIDMLKPIINDKKEYFVIGGGEIFSLLLPYTEKIYMTKIHHNFIGDTFFPNINRYDWNTTKEIQGITDEKNVYNHTFLILNR YP_358159.1 dihydrofolate reductase [Pelobacter carbinolicus DSM 2380] Length: 167. Score: 417. Identity: 34%. E-value: 6E-39. Query: 41 VSGKHSMISLIAALAVDRVIGMENAMPWNLPADLAWFKRNTLNKPVVMGRHTWESIGRPLPGRKNIVISSKPGTDDRVQWVKSVDEAIAAC-GDEPEIMVIGGGRVYEQFLPKAQKLYLTHIDAEVEGDTHFPDYEPDDWESVFSEFHDADAQNSHSYCFEILERR Sbjct: 9 VCTNSKQMTIVVAMTAERIIGRRGQLPWSIPEDLALFRRLTYGHTLVMGRRTFESIGRPLPGRFNIVVSRSMPPVEGLRVCRHFAEALQVADQGNGDIFFIGGCEIYRQALIVAGKLSVSWIRKNYPGDCRFPEYRSDDWLIEQEQDYS-------EFRHIIYRRR ZP_03945215.1 dihydrofolate reductase [Lactobacillus fermentum ATCC 14931] Length: 167. Score: 416. Identity: 31%. E-value: 6E-39. Query: 45 HSMISLIAALAVDRVIGMENAMPWNLPADLAWFKRNTLNKPVVMGRHTWESIGRPLPGRKNIVISSKPGTDDRVQW---VKSVDEAIAACGDEPEIMVIGGGRVYEQFLPKAQKLYLTHIDAEVEGDTHFPDYEPDDWESVFSEFHDADAQNSHSYCFEIL Sbjct: 1 MVKIAFIWAEDEAGWIGKDNDMPWHLSADLKHFKHLTSGHPVIMGKNTYLSLGRPLPKRTNIVVTRQTTPIEGVTLVNGVNALTDLLANYGEDEEVFIIGGAHLFASTMSLATVLYRTVVEGDHHGDVKMAPIDYRTWQKV-AERHLQATESDPACTFEKW ZP_03487511.1 hypothetical protein EUBIFOR_00069 [Eubacterium biforme DSM 3989] Length: 159. Score: 416. Identity: 31%. E-value: 7E-39. Query: 46 SMISLIAALAVDRVIGMENAMPWNLPADLAWFKRNTLNKPVVMGRHTWESIGRPLPGRKNIVISSK-PGTDDRVQWVKSVDEAIAACGD-EPEIMVIGGGRVYEQFLPKAQKLYLTHIDAEVEGDTHFPDYEPDDWESVFSEFHDADAQNSHSYCFEILERR Sbjct: 1 MKLTLIAAIGKNRELGKNNDMIWHLPQDLKFFRQETSGHTIVMGRKTFESLPGKLPKRHHVVISRTCKDLGEDIEMCESVEEFMKRYKDVDEEIYCIGGGMIYSEMLKYASRLVLTQIDADADAEVYFPEFDESLYNK---KILSNIEENGVFYQHVEYTLK ZP_02430941.1 hypothetical protein CLOSCI_01157 [Clostridium scindens ATCC 35704] Length: 173. Score: 414. Identity: 33%. E-value: 1E-38. Query: 42 SGKHSMISLIAALAVDRVIGMENAMPWNLPADLAWFKRNTLNKPVVMGRHTWESIG--RPLPGRKNIVISSKPGTD-DRVQWVKSVDEAIAACGDE--PEIMVIGGGRVYEQFLPKAQKLYLTHIDAEVEGDTHFPDYEPD-DWESVFSEFHDADAQNSHSYCFEILER Sbjct: 5 TGGNSRMNLIVAVDKNWAIGNGNKLLVSIPQDMKFFRETTKGKVVAMGRKTLESFPGGQPLKNRVNVVLTTDQNYKANGAVIVHTIEQMLAELKKYASEDIFVIGGESIYRQLLPYCSKAYVTRIDHAYDADTHFPDLDVDPQWEMT--KISDEQTYFDLEYVFTIYER ZP_00999790.1 Dihydrofolate reductase [Oceanicola batsensis HTCC2597] Length: 178. Score: 413. Identity: 35%. E-value: 2E-38. Query: 47 MISLIAALAVDRVIGMENAMPWNLPADLAWFKRNTLNKPVVMGRHTWESIG-RPLPGRKNIVISSKPGTDDRVQWVKSVDEAIAACGDEP--EIMVIGGGRVYEQFLPKAQKLYLTHIDAEVE-GDTHFPDYEPDDWESVFSEFHDADAQNSHSYCFEILERR Sbjct: 19 MITLVVARDRNGAIGKDGGIPWHLPGDLKMFQRETTGGALIMGRHTWESLPAKPLNRRLNIVVTSRPDTAK--LICETVGEAVRLAEAEGYFRIYGIGGAGIYRDMLPLADRLLVTEVETAVENADTFFPEFDEEEWQETTR----ATAAGDPGYAVRELIRK C2E963 Dihydrofolate reductase - Lactobacillus ruminis ATCC 25644 Length: 173. Score: 410. Identity: 28%. E-value: 3E-38. Query: 41 VSGKHSMISLIAALAVDRVIGMENAMPWNLPADLAWFKRNTLNKPVVMGRHTWESIGRPLPGRKNIVISSKPGTD------DRVQWVKSVDEAIAACGDEPE--IMVIGGGRVYEQFLPKAQKLYLTHIDAEVEGDTHFPDYEPDDWESVFSEFHDADAQNSHSYCFEILERR Sbjct: 1 MTGGTEMLAYIWAEDSAHHIGINGRLPWHLPNDLAYFKRQTSGHPMIMGKKTFDSFPKLLPGRLHVILTHSIEFEKEYADNDQVVVVHNENDLRKWLEEHDSEITFVIGGASLFKMFKDDVDLLYVTKIKEKFDADTTMPDLDMDRFALKYEEKGTTDEKNQYQHTFFVYERK B8BKI9 Putative uncharacterized protein - Oryza sativa subsp. indica Length: 404. Score: 408. Identity: 26%. E-value: 5E-38. Query: 34 YSGDNFFVSGKHSMISLIAALAVDRVIGMENAMPWNLPADLAWFKRNT-------LNKPVVMGRHTWESIG---RPLPGRKNIVISSKPGTD----DRVQWVKSVDEAIAACGDEP------EIMVIGGGRVYEQFL--PKAQKLYLTHIDAEVEGDTHFPDYEPDDWESVFSEFHDADAQNSHSYCFEILER Sbjct: 4 TLSNDVSQNGPQRNYQVVVAATRDMGIGKDGVLPWKLLGDLKFFKELTVTTADPVKKNAVIMGRKTWESLPLKARPLPGRLNIILTRSGSFEFATVENVVICGSMNSALELLSSTPYCLSIEKVFVIGGGQVLRESLNGPSCEAVHLTDIQSSIECDTFIPPIDLSVFQPWYSSLPVV--ESNIRHSFVTYVR NP_001067911.1 Os11g0484400 [Oryza sativa (japonica cultivar-group)] Length: 696. Score: 407. Identity: 26%. E-value: 7E-38. Query: 34 YSGDNFFVSGKHSMISLIAALAVDRVIGMENAMPWNLPADLAWFKRNT-------LNKPVVMGRHTWESIG---RPLPGRKNIVISSKPGTD----DRVQWVKSVDEAIAACGDEP------EIMVIGGGRVYEQFL--PKAQKLYLTHIDAEVEGDTHFPDYEPDDWESVFSEFHDADAQNSHSYCFEILER Sbjct: 184 TLSNGVSQNGPQRNYQVVVAATRDMGIGKDGVLPWKLLGDLKFFKELTVTTADPVKKNAVIMGRKTWESLPLKARPLPGRLNIILTRSGSFEFATVENVVICGSMNSALELLSSTPYCLSIEKVFVIGGGQVLRESLNGPSCEAVHLTDIQSSIECDTFIPPIDLSVFQPWYSSLPVV--ESNIRHSFVTYVR