P0AA37 is a cross-reference for ZP_05439238.1, which is represented by ZP_03440234.1 in NRDB40.
| Set | Shortcuts | Acc.No. | Identifier | Database | Description |
|---|---|---|---|---|---|
| NRDB | IBP | ZP_05439238.1 | 256025373 | RefSeq | 23S rRNA/tRNA pseudouridine synthase A [Escherichia sp. 4_1_40B] |
| NRDB40 | IBP | ZP_03440234.1 | 217324150 | RefSeq | pseudouridine synthase, RluA family [Escherichia coli O157:H7 str. TW14588] |
PSI-BLAST Results for ZP_03440234.1 against NRDB40
Filtering conditions for the hit sequences
- E-value is less than
Matches:
[1-50][51-100] [101-150] [151-200] [201-250] [251-300] [301-350] [351-400] [401-450] [451-500] [501-550] [551-600] [601-650] [651-700] [701-750] [751-800] [801-850] [851-900] [901-950] [951-1000] [1001-1050] [1051-1086]
Match Overview
| Score | E-value | Shortcuts | Acc.No. | Description | ||
|---|---|---|---|---|---|---|---|
  | - | IBP | ZP_03440234.1 | pseudouridine synthase, RluA family [Escherichia coli O157:H7 str. TW14588] | |||
  | 533 | 3E-52 | IBP | ZP_02883511.1 | pseudouridine synthase, RluA family [Burkholderia graminis C4D1M] | ||
| 532 | 4E-52 | IBP | YP_002460468.1 | pseudouridine synthase, RluA family [Desulfitobacterium hafniense DCB-2] | ||
| 531 | 6E-52 | IBP | YP_558676.1 | ribosomal large subunit pseudouridine synthase D [Burkholderia xenovorans LB400] | ||
| 531 | 6E-52 | IBP | ZP_01852455.1 | ribosomal large subunit pseudouridine synthase [Planctomyces maris DSM 8797] | ||
| 530 | 8E-52 | IBP | YP_001035034.1 | ribosomal large subunit pseudouridine synthase D, putative [Streptococcus sanguinis SK36] | ||
| 529 | 9E-52 | IBP | YP_001598812.1 | ribosomal large subunit pseudouridine synthase D [Neisseria meningitidis 053442] | ||
| 525 | 2E-51 | IBP | YP_387941.1 | pseudouridine synthase, RluD [Desulfovibrio desulfuricans subsp. desulfuricans str. G20] | ||
| 523 | 4E-51 | IBP | YP_001280463.1 | RluA family pseudouridine synthase [Psychrobacter sp. PRwf-1] | ||
| 523 | 5E-51 | IBP | ZP_01802060.1 | hypothetical protein CdifQ_04003029 [Clostridium difficile QCD-32g58] | ||
| 522 | 6E-51 | IBP | C5VRN0 | Ribosomal large subunit pseudouridine synthase D - Clostridium botulinum D str. 1873 | ||
| 517 | 2E-50 | IBP | C0BNA6 | Pseudouridine synthase - Flavobacteria bacterium MS024-3C | ||
| 516 | 3E-50 | IBP | YP_002005371.1 | 23S rRNA pseudouridine synthase [Cupriavidus taiwanensis] | ||
| 516 | 3E-50 | IBP | YP_391639.1 | pseudouridine synthase, RluD [Thiomicrospira crunogena XCL-2] | ||
| 512 | 9E-50 | IBP | ZP_01877608.1 | 23S rRNA/tRNA pseudouridine synthase [Lentisphaera araneosa HTCC2155] | ||
| 511 | 1E-49 | IBP | YP_604075.1 | pseudouridine synthase, RluD [Deinococcus geothermalis DSM 11300] | ||
| 511 | 1E-49 | IBP | YP_379918.1 | pseudouridine synthase, RluD [Chlorobium chlorochromatii CaD3] | ||
| 508 | 2E-49 | IBP | B8K915 | Pseudouridine synthase - Vibrio parahaemolyticus 16 | ||
| 508 | 2E-49 | IBP | YP_002297936.1 | ribosomal large subunit pseudouridine synthase D, putative [Rhodospirillum centenum SW] | ||
| 507 | 3E-49 | IBP | YP_422549.1 | pseudouridylate synthase, 23S RNA-specific [Magnetospirillum magneticum AMB-1] | ||
| 505 | 5E-49 | IBP | ZP_01311850.1 | Pseudouridine synthase, RluD [Desulfuromonas acetoxidans DSM 684] | ||
| 504 | 7E-49 | IBP | YP_001087541.1 | putative pseudouridylate synthase [Clostridium difficile 630] | ||
| 502 | 1E-48 | IBP | B9AQ21 | Pseudouridine synthase - Prevotella copri DSM 18205 | ||
| 500 | 2E-48 | IBP | C4WHT4 | Pseudouridine synthase, RluA family - Ochrobactrum intermedium LMG 3301 | ||
| 500 | 2E-48 | IBP | ZP_04791326.1 | pseudouridine synthase, RluA family [Desulfovibrio vulgaris RCH1] | ||
| 499 | 2E-48 | IBP | YP_247357.1 | ribosomal large subunit pseudouridine synthase D [Rickettsia felis URRWXCal2] | ||
| 500 | 2E-48 | IBP | YP_001741511.1 | Pseudouridylate synthase, 23S RNA-specific [Candidatus Cloacamonas acidaminovorans] | ||
| 497 | 4E-48 | IBP | C5AFL0 | Pseudouridine synthase RluD - Burkholderia glumae BGR1 | ||
| 494 | 9E-48 | IBP | C0QV86 | Pseudouridine synthase - Brachyspira hyodysenteriae (strain ATCC 49526 / WA1) | ||
| 494 | 1E-47 | IBP | C1SCP2 | Pseudouridine synthase - Cryptobacterium curtum DSM 15641 | ||
| 491 | 2E-47 | IBP | ZP_05069084.1 | pseudouridylate synthase [Candidatus Pelagibacter sp. HTCC7211] | ||
| 491 | 3E-47 | IBP | YP_595188.1 | pseudouridylate synthases, 23S RNA-specific [Lawsonia intracellularis PHE/MN1-00] | ||
| 489 | 4E-47 | IBP | YP_003048314.1 | pseudouridine synthase, RluA family [Methylotenera mobilis JLW8] | ||
| 488 | 5E-47 | IBP | YP_616788.1 | pseudouridine synthase, RluD [Sphingopyxis alaskensis RB2256] | ||
| 488 | 6E-47 | IBP | YP_001413435.1 | RluA family pseudouridine synthase [Parvibaculum lavamentivorans DS-1] | ||
| 487 | 7E-47 | IBP | YP_264541.1 | ribosomal large subunit pseudouridine synthase D [Psychrobacter arcticus 273-4] | ||
| 486 | 8E-47 | IBP | YP_277698.1 | pseudouridine synthase [Candidatus Blochmannia pennsylvanicus str. BPEN] | ||
| 486 | 9E-47 | IBP | YP_001550096.1 | putative pseudouridylate synthase specific to ribosomal large subunit [Prochlorococcus marinus str. MIT 9211] | ||
| 485 | 1E-46 | IBP | A8YDR1 | Pseudouridine synthase - Microcystis aeruginosa PCC 7806 | ||
| 483 | 2E-46 | IBP | YP_003051480.1 | pseudouridine synthase, RluA family [Methylovorus sp. SIP3-4] | ||
| 484 | 2E-46 | IBP | YP_001939799.1 | Pseudouridylate synthase, 23S RNA-specific [Methylacidiphilum infernorum V4] | ||
| 483 | 2E-46 | IBP | C1SUB8 | Dephospho-CoA kinase - Desulfohalobium retbaense DSM 5692 | ||
| 482 | 3E-46 | IBP | ZP_03010365.1 | hypothetical protein BACCOP_02239 [Bacteroides coprocola DSM 17136] | ||
| 481 | 3E-46 | IBP | ZP_04759077.1 | pseudouridine synthase, RluA family [Zymomonas mobilis subsp. mobilis ATCC 10988] | ||
| 481 | 3E-46 | IBP | YP_002508581.1 | pseudouridine synthase, RluA family [Halothermothrix orenii H 168] | ||
| 482 | 3E-46 | IBP | YP_001512713.1 | RluA family pseudouridine synthase [Alkaliphilus oremlandii OhILAs] | ||
| 479 | 6E-46 | IBP | NP_692143.1 | pseudouridine synthase [Oceanobacillus iheyensis HTE831] | ||
| 478 | 7E-46 | IBP | ZP_03642828.1 | hypothetical protein BACCOPRO_01187 [Bacteroides coprophilus DSM 18228] | ||
| 478 | 8E-46 | IBP | ZP_01612711.1 | ribosomal large subunit pseudouridine synthase A [Alteromonadales bacterium TW-7] | ||
| 478 | 8E-46 | IBP | ZP_02211204.1 | hypothetical protein CLOBAR_00817 [Clostridium bartlettii DSM 16795] |
Stacked Multiple Aligment
1 1 1 1 1 1 1 1 1 1 2 2 2 2 2 2 2 2
1 2 3 4 5 6 7 8 9 0 1 2 3 4 5 6 7 8 9 0 1 2 3 4 5 6 7
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The representative sequence for the query: MGMENYNPPQEPWLVILYQDDHIMVVNKPSGLLSVPGRLEEHKDSVMTRIQRDYPQAESVHRLDMATSGVIVVALTKAAERELKRQFRERVPKKQYVTRVWGHPSPAEGLVDLPLICDWPNRPKQKVCYETGKPAQTEYEVVEYAADNTARVVLKPITGRSHQLRVHMLALGHPILGDRFYASPEARAMAPRLLLHAEMLTITHPAYGNSMTFKAPAVFLTFPVRLYPHPKGCLLYINPRVRGFFVSAKLLSVVACGYAFHSVIPFLLHSEFLNFFFTR
ZP_03440234.1 pseudouridine synthase, Rl MGMENYNPPQEPWLVILYQDDHIMVVNKPSGLLSVPGRLEEHKDSVMTRIQRDYPQAESVHRLDMATSGVIVVALTKAAERELKRQFRERVPKKQYVTRVWGHPSPAEGLVDLPLICDWPNRPKQKVCYETGKPAQTEYEVVEYAADNTARVVLKPITGRSHQLRVHMLALGHPILGDRFYASPEARAMAPRLLLHAEMLTITHPAYGNSMTFKAPAVFLTFPVRLYPHPKGCLLYINPRVRGFFVSAKLLSVVACGYAFHSVIPFLLHSEFLNFFFTR
ZP_02883511.1 pseudouridine synthase, Rl -------TPEPVPLEIVYEDDTLVVINKPAGMVVHPAAGNWSGTVLNGLLYRYLPRAGIVHRLDKETSGLMVVARTLEAQTDLVRQLQARTVKRRYLALVWGNMP-EEGTIDAPIGRDPRERTRMVVTGASGKPARTHFRRVDWQRQPVTAIHCDLETGRTHQIRVHCAHIGHPLLGDPVYGRARLPGEFARQALHAWRLGLIHPKTGRTMQWRAPADIAALSAALGLGRDDA----------------------------------------------
YP_002460468.1 pseudouridine synthase, Rl --------AENIPLEILYEDEDVLVVNKSQGMVVHPAPGAWTKTLVNALLYHCRNRPGIVHRIDKDTSGLLVVAKNDLAHQGLAEQIKAHSMARRYLAIVHGVVFEPSGTVEAPIGRDPADRKKMAVVFQNAKEAVTHYEVLERFRD-FTLLEARLETGRTHQIRVHMAYLKHPVLGDPLYGPRKNPFGLQGQMLHAQLLGFQHPRSGEYMEFSAPASFQKVLEEIRRDD-------------------------------------------------
YP_558676.1 ribosomal large subunit ps -------TPEPVPLEIIYEDDTLVVINKPAGMVVHPAAGNWSGTLLNGLLYRYLPRAGIVHRLDKETSGLMVVARTLEAQTDLVRQLQARTVKRRYLALVWGNMP-EEGTIDAPIGRDPRERTRMVVTSAAGKPARTHFRRVDWERQPVTAIHCDLETGRTHQIRVHCAHIGHPLLGDPVYGRARLPGGFARQALHAWRLGLIHPKTGRTMQWRAPEDMEALSAALGLGRDDA----------------------------------------------
ZP_01852455.1 ribosomal large subunit ps ----NRLPPEDIPIDIVYEDDWIAIINKPSDMIVHPGKGNYAGTLAGALQYHFDQRPGIVHRLDRNTSGIMVVAKDNQVHAKLSAQFEKRDVQKEYRAIVWGRMEFDTDYIDTFMCVHPRAREKMIVCDEGGNAAFTYYEVIER-YQAFTYVRLKPRTGRTHQLRVHMQHIGHSIVADRVYGGLESDVLIERQALHAYCLEFFHPQSGKPMKFEAPLPMQNTLAALDQYQKEV----------------------------------------------
YP_001035034.1 ribosomal large subunit ps -----EYVAEDIPLEIVYQDEDVAVINKPQGMVVHPSAGHTSGTLVNALMYHIQDRPGIVHRIDKDTSGLLMIAKNDQAHVALADELKDKKSLRKYWAIVHGNLPNDRGVIEAPIGRSEKDRKKQAVTAK-GKPALTRFQVLER-FGDYSLVELQLETGRTHQIRVHMAYIGHPVAGDEVYGPRKTLKGH-GQFLHARTLGFTHPRTGEVLEFTAEVPFQETLEKLRQ---------------------------------------------------
YP_001598812.1 ribosomal large subunit ps -------VPEPMALDIVYEDDTVIVVNKPAGLVVHPAAGNWTGTLLNGLLAHQVPRAGIVHRLDKETSGLMVVAKTLPAQNSLVQQLQERTVKRIYRAVANGIVPFD-GKIETQIGRDPHNRLKMAVVKFGGKPAVTHVKVLERYL-AHSYIECSLETGRTHQIRVHMREANHPLAADPVYGNPRHKSLGARQALHAYRLSFTHPKTGETRSFEAPIP-------------------------------------------------------------
YP_387941.1 pseudouridine synthase, Rl --------PEEGELEVLYRDAHMLVINKPAGLTVHPAPSCPEGTLVHRLLHHFPERPGIVHRIDKDTSGLLLIALTEKARLALSDAFAGRRIHKEYLALVKGIPEGDSGEIDAPVGRHPTHKTRMAVVR-GGREALSTWRVLGGGGTGWTLVAVRIHTGRTHQIRVHMQHTGHPLWGDALYGGMPGREELQRQMLHAWKISFDHPVTGAPMQFTLPPPFGTLIRDLGSRCQRVVITGMP---GCGKSAVL-----------------------------
YP_001280463.1 RluA family pseudouridine LEQHGSDQPEDIKLDIIYEDDSVIVINKPVGMVVHPGAGNWSGTLVNGLLYHHLPRAGLVHRIDKNTSGLLVIGKTKAAQLELQEQLKDKSVYRHYQCVVAGDAPSRQRTIDAPIGRHRTQRTKMTVTST-GKTAITHIMKITPLSDTYSLLDVRLETGRTHQIRVHLSHIGHPIIGDDIYGNRQQLRAFPRQALHAYKLGFIHPETGESIELTAPLP-------------------------------------------------------------
ZP_01802060.1 hypothetical protein CdifQ --------PQDIPIDIVYEDDDVLIINKPQDMVVHPAPGNYENTLVNGILYHCKDRPGIVHRIDKDTSGLLMIAKNNYAHNFLAEQLKEHTITREYEFICYGVVKEDKITVDKPIGRNPKDRLKMAV-VKDGKNAITHFEVVERF-DKFTHMRARLETGRTHQIRVHALSINHPLLGDFVYGPKETKFKLKGQTLHAKKLGFIHPTTKEYIEFELPEYFKEAIKKIK----------------------------------------------------
C5VRN0 Ribosomal large subunit ps --EEQDIIPEKMDLDIIYEDNDIIVVNKPKGIVVHPTKRHLNGTLSNGVLYYFNDKVRLVNRLDMDTSGLVLIAKNAYSHMALSRDMQKDDFVKKYLAIVHGNFNEDSGVIDKPIYRVGEGTLKRII-DERGQRSITLFKVIE-QYKNASLVELTLETGRTHQIRVHLSSIGHPIYGDSLYG-EEEPQYIDRQALHAYKLQIPHPKDGKILKLESPEDMKNLIRKLSE---------------------------------------------------
C0BNA6 Pseudouridine synthase - F ------LTPEDIPLDVVYEDSDLMVVNKPPGMVVHPGHGNYSGTLINALLFHVKERPGLVHRIDKDTSGLLVVAKTAKAMTHLAKQFFDKTSEREYVAIVWGNVEEEQGTVRGHIGRHPKNRLQMAVFPDGGKEAVTHYKVMER-LGYVTLVSCVLETGRTHQIRAHMKHIGHTLFNDERYGGEKILKGLPRQALHAKTLGFVHPSSGELMRFNTPIP-------------------------------------------------------------
YP_002005371.1 23S rRNA pseudouridine syn --------PEDVPLDVVYEDDTLLVINKPAGLVVHPAAGNWSGTVLNGLLHRDLPRAGIVHRLDKETSGLMVVARTLTAQTDLVRQLQARTVKRTYIALVWGR-TYDEGTIDAPIGRDPRERTRMIVQTASGKPSRTHFRTLATVPGFVSMVMCKLETGRTHQIRVHFESIGHPLVGDPVYFRATQRGQRPRQALHAYKLGLVHPATGKHMSWTAPEDLQALIDAL-----------------------------------------------------
YP_391639.1 pseudouridine synthase, Rl IEDEVSYQAQDIPIEVVYEDEDILVLNKPAGLVVHPGAGNPDGTLLNALLFHYEPRAGIVHRLDKETSGLMVVAKNVPAQTHLVEQLQQHDVERVYDAIVVGKMISG-GTISKPIGRHPTDRKRMAVLTVGGKPATSHYRVLERFRE-HTHVRVKLETGRTHQIRVHMAYLGFPLVGDPVYAGRDYLRGFKRQALHAGQLSLTHPRTGKTMKWKVPDDMLELIDILRDDMED-----------------------------------------------
ZP_01877608.1 23S rRNA/tRNA pseudouridin ---ESTLLPEDIELDIIYEDDDILVVNKPAGMVVHPGAGNYTGTLVNALLGRDLDRPGIVHRLDKETSGVIIVAKSAKNLDKLSRSFARRDVEKYYVALCRGTIRVGRDTITSHIGRSRSNRQKMTNDSNRGKEAISHYKVLADNNGA-TLVKLKIDTGRTHQIRVHMSGINHPVVGDKLYGVRRLDEKPDRHILHAWRTRIIHPGTQEIMTFTAPLDFKSVCDKFG----------------------------------------------------
YP_604075.1 pseudouridine synthase, Rl --------PEAVPLDVLYEDEHLIAVNKPPGMVTHPAPGVTSGTLVNALLGRDGYRPGIVHRLDKDTSGVIVVAKTVEAHARLAAAFKDRSTHKTYLAIAAGMWKQGPVSVNAPVGRHPTARQRMTVGGVGPREAQTLFTPLATHPDGHALVRAQPHTGRTHQIRVHLAHLGSPILGDAVYGRASA--VMPRHALHAQFLTLPHPVTGETLHLHAPVP-DDLLRAWVALGGAVPAELEAPSRG------------------------------------
YP_379918.1 pseudouridine synthase, Rl -----ELAPEAIPIAIMYEDDDLMVINKEPGMVVHPAFGNWTGTLANAILHHLGNRPGIVHRLDKDTSGLIIIAKNPIALHKLARQFAERKVGKIYKALTWGVPKQASGTITTNIGRSHKNRKVMANFPFEGLEGKTAITCVEENLEWFSVMSLRLHTGRTHQIRVHLQHLGLPIVGDVTYGGATPRELLPRQALHAETLTFHHPTTGEEITLSAPLP-EDMLQALEKIRGICKL--------------------------------------------
B8K915 Pseudouridine synthase - V MAMTEYNPPREPWVDIVFEDEHILVANKPSGLLSVPGRLEEHYDSLWSRLVAIYPDIQVVHRLDMDTSGLMLLAKHKEAERSLKKQFQYRLTHKVYYARVWGHPTNDNGEIDLPLICDWPNRPRQIVCFDDGKPSKTLYQVVKR-EERTSIVRLLPITGRSHQLRVHMQALGHPIVGDEFYSEGEAFEFSDRLELHAAELSFYHPHSEALQCAFVPCDF------------------------------------------------------------
YP_002297936.1 ribosomal large subunit ps --------PQAIPLAIVHEDEDLLVIDKAAEMVVHPAAGNPDGTLVNALLAHCGDRPGIVHRLDKGTSGLLVAAKTDRAHQGLTAQFADRSLSRTYLAVVWGVPAAREGVIEGNIGRHPGDRKRMAVLSRGGKPAVTRYRVVRSFGLLASLVECKLLTGRTHQIRVHMAHVGHPLVGDPLYGRLRPPRGFPRQALHAAALEFRHPASDLKLGFTAPEDLAGLIQGLETL--------------------------------------------------
YP_422549.1 pseudouridylate synthase, -DAPAQPEPQDIALTVVYEDEDLIVIDKPAGMVVHPAPGNPDETLVNALLAHCGERPGIVHRIDKDTSGLLVAAKTDAAHRGLATQFAAHTLERAYWALVWGTPSPRQGEIEGNIGRNPNDRKKMAVVKSGGKPALTRYRVLKSFGGAVSLVECRLATGRTHQIRVHMTTQGHPLVGDPVYGRIRGHKGFPRQALHAYLLGFSHPTKGYDVRFESPLDINALMQILEVL--------------------------------------------------
ZP_01311850.1 Pseudouridine synthase, Rl --------PEDLPLTVLYEDSDLIVINKAAGMVVHPAAGHSSGTLVNALLYHCHDRPGIVHRLDKDTSGVMVATKNDVTHNHLAAQFKDHSIQRRYVALVHGQVQNARGTIDAPIGRHPTHRKKMTSKGRGGRRAVTHWKVLRRYDDRLSLLEMRLETGRTHQIRVHLSEMNLPLVGDPLYGNRTRANGLHRQALHARLLGFIHPRTGDYLEFTSDLP-------------------------------------------------------------
YP_001087541.1 putative pseudouridylate s -EEKANFEPQDLNLQIIYDDFDIIMVNKPPFMVVHPTKSHYDKTIANGISQKENVKIRFVNRLDMNTSGLVIVAKNAYAHHTLSTAMSENKVEKKYITVVDGIIKENEGTIDEPIYRPTEDSIKRII-DERGQSSVTHYKVIER-LENATVLEVSLETGRTHQIRVHMAHIGHGIIGDELYGYVDEE-LINRQALHAYKLEFEQPRTKEKLKFKAPEDMKELISKLR----------------------------------------------------
B9AQ21 Pseudouridine synthase - P LDRPRHETPEEIAINVVYEDDQLMVVNKEAGMVVHPGAGNFHGTLIQAVAWHLRPEVGLVHRIDKDTSGLLVVAKTPTAKNALGKQFFNKTTHRSYNALVWGNIVEDEGRIEGNIGRDPKNRLRMKVFDPDGKTAVTHYKVLER-FGYTTLVQCVLETGRTHQIRAHMKHIGHPLFMDETYGGTEILRLCPRQALHAKTLGFVHPTTKQQMDFDSPNDFRQLIEK------------------------------------------------------
C4WHT4 Pseudouridine synthase, Rl VVLPEPEPAEPIPLDILYEDDDLIVINKPAGLVVHPGNGNWTGTLVNALIYHCGDRPGIVHRLDKDTSGVMVVAKNDLSHRHLSEQFADHGLERAYLALVWGMTERPQGYIDAHLGRSHRDRTKQAVVNEDARHAITHYATVEKFGPRESLVECRLETGRTHQIRVHMAHIGHPLVGDMDYGSKEAVRGFHRQALHAFLLAFTHPSSGELMRFEAPVPMKHLLENFRKHS-------------------------------------------------
ZP_04791326.1 pseudouridine synthase, Rl --------PEEGDLTIIHRDEHLLVIDKPAGLTVHPCPSCPEGTLVHRLVHHEGFRPGIVHRIDKDTSGLLLVALSEGVRLKLSEAFAERTVEKEYLALVHGVPP-ATGEVDAPIGRHPTHKVRMAV-VKGGKPARSEWRVLHAPEGHYALVAVRIHSGRTHQIRVHMAHAGFPLWGDQLYGPGTPARLRERQMLHAWHLAFTHPVTGERLRFTCPPPFPDLAIALARRMTRVVITGSP---GCGKSALL-----------------------------
YP_247357.1 ribosomal large subunit ps --EELKIAAANIALDIIYEDDDLIVINKAAGMTVHPGAGHHDDTLVNALLYHTKERPGIVHRLDKDTTGLMVVAKNNKAHMLLANQIEQRQVIRKYKALVWGVINPLEGVIKNNIGRSRVDRQKMTILKYGGKEAVTHYKTLEFHKGTISMVECKLSTGRTHQIRVQLSHLKHSVVGDQTYGNNDRKIDFKRQALHSWYLSFTHPTSNEIMKFSCELP-------------------------------------------------------------
YP_001741511.1 Pseudouridylate synthase, INLPEPEPPQDIPLDVVYEDEYLAIINKKAGMIVHPGFGNPEGTLVNAILYKEFNRPGIVHRLDRGTSGLIIIAKNDLTHAKLSDMFARREIKKTYFAITTGIPEPEKGEIETYLAR-SNKNPRTICVTNEGRYALTHYKTIKTWH-YFALVEINPATGRMHQIRVHFAHIRYPILGDLLYNSRRLVNHLRRQALHSWKLEFFHPITGYPISVSAPIP-------------------------------------------------------------
C5AFL0 Pseudouridine synthase Rlu -------TPEPVPLAIVYEDEALVVIDKPAGLVVHPAAGNWNGTLLNGLLHRYLPRAGIVHRLDKETSGLMVVARTLAAQTDLVRQLQARTVKRRYFALVWGRTP-ASGTIDAPIGRDPRERTRMVVTGASGKPARTHFRTVDWQNQPVSAIQCDLETGRTHQIRVHCAHLGHPLLGDPVYGRARLPDGFARQALHAWRLGLVHPVTGRSMQWRCAVP-------------------------------------------------------------
C0QV86 Pseudouridine synthase - B -------IPENIDLDILYEDKYLLVINKPAGMSVHCSPSEMSGTLVNALLYKNKERAGIIHRLDKDTSGLMIIGKNANIVSSIQEQFKNRTIKKIYHAIVVGVLKDNYIEINLPIGRHHVYRKKMTV-REDGKEALTHIKVLKR-FNSHTLIEINLKTGRTHQIRVHSSYKGFPVAGDKIYSKSFSK--YSGLMLVAKKIEFMHPITKELLDFEIPDYFTNFL--------------------------------------------------------
C1SCP2 Pseudouridine synthase - C ---------EPIPLDVRFEDRWMMAISKQAGLCVHPAPGHEGGTLVNALIYAYGDRPGIVHRLDMDTSGLMMCAKDDTCGMALQDLVRDHKVDRRYLTLVHGNIAFDTGQIDEPIGRVGDDRLRMKIYRPTARNALTTFTVLERFDNGYTLLECRLYTGRTHQIRVHMEFIGHCCVGDPLYGNEQVNLELSRQFLHSYSLSFNHPMTGDDIALVDGLP-PDLFGALRSLEDRSMGRTEAGKRIFATLATAPRQSEELQAHYF-----------------
ZP_05069084.1 pseudouridylate synthase [ --EEASLKPYKFKLDIIYEDEDLLVINKPAGIIMHPGAGNYDKTIVNALMNYDKDRPGIVHRIDKNTSGLVVVAKNNETHESLSKQFSDHSITRVYQLLIWGKLRPSSGKIDTFITRSSKNRQLMEVSRSKGKRAITNYKTIKIFESNKTLIECKLETGRTHQIRVHMTYMGNSIVGDDKVGLENLISKLKRQFLHAKTLGFVHPKTDKEMIFSSNLPLNNLLKMLKNTD-------------------------------------------------
YP_595188.1 pseudouridylate synthases, --------PEEGFLEILFSDEHLAIINKPPGLTVHPAPSCQESTLVHRLLKYFPKRPGIVHRIDKDTSGLLCIALTEDTRLKLSKIFLDRKINKEYLALVHGVPSM-EGYIAVPLGRDPKTKVKVAVN-PKGKPAHTEWRVLHRGKNDYSILALTIQTGRTHQIRVHMKHIGHPLVGDKLYAGGHVNKTFNRQMLHAWKLSFEHPITGKKMNFLCPPPFLDTVSLLEQEPIRIVIT-------------------------------------------
YP_003048314.1 pseudouridine synthase, Rl --ESRAFIAQDIPLDIVYEDDHILVVNKPAGMVVHPAAGNWDGTLLNALLFHDVPRAGIVHRLDKETSGLLVVAKTLNAQTHLVRQLQARTVKREYRAIVWGQL-WRNGVVDQPLGRDPRSRTKMAINRM-GKPAITRYEILERFSV-QTYLRCNLETGRTHQIRVHMQHLKAPLVGDPVYGFRDAVSQFHRQALHAIKLGLVHPATNEFMEWQIELDMKVLLEAMRH---------------------------------------------------
YP_616788.1 pseudouridine synthase, Rl --LPAHNAAQDLDLVIAYEDAHLIVIDKPAGMVVHPAAGNLDGTMVNALLHHCAGRPGIVHRIDKDTSGLIVAAKHDKAHEGLAKQFAAHSIDRRYLAIATGRPMPANGTVDAALGRSATNRKKMAVVAAGGKHALTHYRTVEPLQGA-TLIECRLETGRTHQVRVHMAHIGHPLVGDPVYGRARKPRNFARQALHAAHLGFIHPVTGNRIALELPADMRELIDELR----------------------------------------------------
YP_001413435.1 RluA family pseudouridine ---------QAIPLEIVYEDADLIVVMKPAGLVVHPAPGNPDMTLVNALVAHCGERPGIVHRLDKETSGLMVVAKTDRAHQGLSAQFRDGKLTRAYTALTWGVPQTRKGTVDANIARSSHNRSKMATVRDGGRIAITHYTVTDYADGLVAEVECRLETGRTHQIRVHMTALGHPLLGDATYGAQAALERLNRQALHAHHLGFEHPVAGEKMSFDAPLPMQELVRALEGVRDG-----------------------------------------------
YP_264541.1 ribosomal large subunit ps LEQHSADQPEDIAIDVVYEDDEVLVINKPVGMVVHPGAGNQAGTLVNALLHHHLPRAGLVHRIDKDTSGLLLIGKTKPAQLALMEQLKDKSVYRHYQCVVAGDAASRHRRIDAPIGRHRNQRTKMTVMTA-GREAVTHLLNVTALNGNYCLLDVGLETGRTHQIRVHLSHITYPIVGDRVYGGRRQLRNFPRQALHAYILGFVHPTTGEDIEVTTPMPMQQLMAVL-----------------------------------------------------
YP_277698.1 pseudouridine synthase [Ca ----NNIVPQDIPLDIVYEDDDIVVINKAKNMVVHPGAGNHSGTILNALLYKYPARSGIVQRLDKDTTGLMVVAKNMIAYHSLLRLFKKRKIIREYEAVVLGNFLHNEGTINQPIRRHAVHRTRMTVNPM-GKSAITHYSIIES-FGMYTRIRVRLETGRTHQIRVHMAYINHPLLGDHKYGKNDCLHVLNRQALHAATLQLCHPITRIKMKWDVPLP-KDIIKLINILRKNE----------------------------------------------
YP_001550096.1 putative pseudouridylate s ---------EKISLDILYEDKYLIVINKQAGIAVHPAPGNKFGTLVNGLLHHCNDRPGIVHRLDKDTTGCIVVAKTQEALVNLQKQIQTRVASRIYLAIVHGVPKGDKGTIIGAIGRHPVDRKKYAVVTNEMARYACTHWELKERLGDYSLLSFKLDTGRTHQIRVHCAHFGHPILGDQTYSRKKLPNGVSSQVLHAVKLGLKHPHNNETMLFEAPLPFKNVLTRLQKR--------------------------------------------------
A8YDR1 Pseudouridine synthase - M -------------LEIIYEDEGIIAINKPAGLLSVAGRYQDSQDAVVNRFRRQGKNLIPVHRLDRETSGILLLAKSLDIYRCLSQQFQRREVEKIYEAILSEIIERESGIIDLPLWGNPQNRPYQTVDWQRGKASQTYFKVVG-KEGNYSRLEFIPYTGRTHQIRVHQQGLGIGILGDFLYNGKQSD----RLYLHAKQLSFRHPQTENKLDLIIPTPF------------------------------------------------------------
YP_003051480.1 pseudouridine synthase, Rl ---EHAFEAEDIPLDVQYEDEHILVINKPAGLVVHPAAGNWSGTLLNALLHHDLPRAGIVHRLDKDTSGLLVVAKTLTAQTSLVRQLQARTVKREYRAIVWGQV-WQNGRIDQPIGRHPHARTKMAINR-NGKPAVTRYEVLERFAV-HTYLRCNLETGRTHQIRVHMQHLKAPLVGDPVYGLGGIVPLFGRQALHAVKLGLIHPASGEFMEVELPADMKSLLEAMRLVP-------------------------------------------------
YP_001939799.1 Pseudouridylate synthase, --------AEEIALEILYEDEEILIVNKQRGMVVHPSCGHWSGTLVNSLLFHYGERPGIVHRLDKDTSGVMVIAKTERSLKSLLLQFSQRTVQKVYLCLCKNRFPYLRYSFEANIHRHASDRKKMAVHRLKGKTAETRFTLLFASSQA-SFLKCEPVSGRTHQIRVHLSHLGFPIIGDPLYG-KGVRKYPFPLLLHAYALKIEHPRSGKKIEFMAPLPFKEALD-------------------------------------------------------
C1SUB8 Dephospho-CoA kinase - Des ------IKPEVGPVEVVYSDPDVVVVNKAAGVTVHPGTGCESGTLVHHLARFDGERPGVVHRLDKDTSGLLTVALNESARLALTRSFARREVDKEYLTLVHGRPE-AEGTVDHPLGRDPQSKIRMAVVPRGGKEALTRFKRVWSPDGRVSLLRVRILTGRTHQIRVHMAYLGFPLVGDALYGPQALARLAKHHMLHAWRLAFPHPRSGRMVCCEQAMP-KAMWRLVLGCGRRVQRVGLTGMPGCGKSALLSELSDRGV---------------------
ZP_03010365.1 hypothetical protein BACCO -----ENIHQDTKPEIVYEDDWLVVVNKPAGMLSV--PGKEALNSVYQFLHERYPEPMLVHRLDMATSGLLLAAKDKDTHQKLQALFCGREIKKRYTAVLSSIVNADEGTISLPLCLNFHDRPRQMVSFEYGKPAITRYKVLERKNGK-TLIAFYPLTGRTHQLRVHAAHLACPIVGDELYG-----KRADRLYLHAAELSFIHPVNGEDITICCEADFS-----------------------------------------------------------
ZP_04759077.1 pseudouridine synthase, Rl ---------------VIHRDKAAIVVNKPAGLATQGTKTHYHLDGLLDALQFEAPRPKLVHRLDKDTSGVLLLARSANNAGYFSKAFSGRTAHKVYWALVVGVPSITEGLIDLPLARQPGSGGKMHVDEENGATAKTLYRVIERAGNAACWLELQPLTGRTHQLRAHLSAIGFPIVGDGKYGGKETGGVSRKMHLHARRLVIPHP-DGSNLDVHADLP-EHFLESMSLLGFDLENGYDRPLGGEKVIDKEAEKIAEG----------------------
YP_002508581.1 pseudouridine synthase, Rl --------PAPLDLDIIYEDRHLLVINKPANMLVHPTPVEKSNTIVNGVLYHMRNQVRPIHRLDRNTTGLLLIAKNQYAHNYITHQFQNNNIHREYLAFVHGNVEFKKESINAPIGKTRDSLIKRKVDHTLGKRAVTHIKVVK-PGGLISLIRVKLETGRTHQIRVHLSHLGHPLLGDTLYGG--EDILIKRPALHSYKVTCCLPFKHKEVTFKAPLPMEKLKKQL-----------------------------------------------------
YP_001512713.1 RluA family pseudouridine -DEPNHFTLQDVPFEAVYEDVDLILVNKEPGIVTHPTKSHPNGAALYLKSKGIDCKVRFVNRLDMDTSGLLIIAKNAYAHHVLSEQMQEDRIEKKYIAFVWGVIKEDEGRIEAPIYRTTMDSIKRVV-DERGQESITEFKVLER-YKNATMVEVKLLTGRTHQIRVHMEHLGHPLIGDTLYGKEDAE-LIDRQALHAEYLRFWQPRFKRAIEVKADLP-ADLLSLRDKLKE------------------------------------------------
NP_692143.1 pseudouridine synthase [Oc ------ITPEKLPLDIIYEDAYCLVVNKPAGQACLPSMNHRH-NTLANGLTYYYQKVHIVTRLDVNTSGLVLVAKNQYVHSLFSRMQQEGNINRVYEAIVHGEVSPTSGIVDAPIARKEGSIIERTVDMRNGKYAKTNYRVL-YADSIASWVEIKLETGRTHQIRVHFQYLGHSLYGDNLYGG--SKDIMLRQALHCKQITMMHPIKNQPIQLEAPEDMGILLKRL-----------------------------------------------------
ZP_03642828.1 hypothetical protein BACCO ----------DTPLEIIYEDPWIVVVNKPAGMLSVPGKNG--LDSVLQRLQELYPEPLLVHRLDMDTSGLLLAAKDKNIHQCLQALFETRQIRKRYTALLQGNPRQDEGTIDLPLCPDFSDRPRQQVNWELGKKAVTRFRVEER-SGGTTRVSFWPLTGRTHQLRVHAAHLDSPILGDPLYGNQ-----ADRLYLHAAELEFTHPVTGETIRLCKEAPF------------------------------------------------------------
ZP_01612711.1 ribosomal large subunit ps ------NPAQGKELTVVYQDDDLVIVNKPAEFLSVPGITID--DSVFLRMKTQFPEPLIVHRLDMSTSGLLIIALNKRAHKAIQKQFIERTIEKRYVALVDGNIEQESGTIELPLTPDFDDKPRQKVCYQKGKPALTTWQVLER-KNNTTRLQLYPKTGRTHQLRVHCAHLNTPIIGDTHYGKK-----ADRLHLHAEYLAFTHPINHERLEFKIDADF------------------------------------------------------------
ZP_02211204.1 hypothetical protein CLOBA ---------QDLNLNIIYDDFDLIMVDKPPFMVVHPTKSHFENTTDYIIKKGEDVKIRFVNRLDMNTSGLVIVAKNPFAQHVLSSEMKDDDFEKKYITVVKGIIEEDEGTINQPIYRPTDDSVKRVV-DERGQESITHYKVIERLNDA-TIVEVKLETGRTHQIRVHMEHIGHPIIGDELYG-FVDENLIKRQALHAYSLKFRQPRTKELLEFKAPEDMKILIQKLK----------------------------------------------------
Pairwise Alignments
ZP_03440234.1 pseudouridine synthase, RluA family [Escherichia coli O157:H7 str. TW14588] Length: 279. Score: 716. Identity: 100%. E-value: 2E-73. Query: 1 MGMENYNPPQEPWLVILYQDDHIMVVNKPSGLLSVPGRLEEHKDSVMTRIQRDYPQAESVHRLDMATSGVIVVALTKAAERELKRQFRERVPKKQYVTRVWGHPSPAEGLVDLPLICDWPNRPKQKVCYETGKPAQTEYEVVEYAADNTARVVLKPITGRSHQLRVHMLALGHPILGDRFYASPEARAMAPRLLLHAEMLTITHPAYGNSMTFKAPAVFLTFPVRLYPHPKGCLLYINPRVRGFFVSAKLLSVVACGYAFHSVIPFLLHSEFLNFFFTR Sbjct: 1 MGMENYNPPQEPWLVILYQDDHIMVVNKPSGLLSVPGRLEEHKDSVMTRIQRDYPQAESVHRLDMATSGVIVVALTKAAERELKRQFRERVPKKQYVTRVWGHPSPAEGLVDLPLICDWPNRPKQKVCYETGKPAQTEYEVVEYAADNTARVVLKPITGRSHQLRVHMLALGHPILGDRFYASPEARAMAPRLLLHAEMLTITHPAYGNSMTFKAPAVFLTFPVRLYPHPKGCLLYINPRVRGFFVSAKLLSVVACGYAFHSVIPFLLHSEFLNFFFTR ZP_02883511.1 pseudouridine synthase, RluA family [Burkholderia graminis C4D1M] Length: 450. Score: 533. Identity: 31%. E-value: 3E-52. Query: 8 PPQEPWLVILYQDDHIMVVNKPSGLLSVPGRLEEHKDSVMTRIQRD------YPQAESVHRLDMATSGVIVVALTKAAERELKRQFRERVPKKQYVTRVWGHPSPAEGLVDLPLICDWPNRPKQ-KVCYETGKPAQTEYEVVE---YAADNTARVVLKPITGRSHQLRVHMLALGHPILGDRFYASPE-------ARAMAPRLLLHAEMLTITHPAYGNSMTFKA--PAVFLTFPVRLYPHPKGC Sbjct: 137 TPEPVPLEIVYEDDTLVVINKPAGMVVHPAAGNWSGTVLNGLLYRYGDAAAGLPRAGIVHRLDKETSGLMVVARTLEAQTDLVRQLQARTVKRRYLALVWGNMP-EEGTIDAPIGRDPRERTRMAVVTGASGKPARTHFRRVDTAIWQRQPVTAIHCDLETGRTHQIRVHCAHIGHPLLGDPVYGRARGKRSVTPLPGEFARQALHAWRLGLIHPKTGRTMQWRADVPADIAALSAALGLGRDDA YP_002460468.1 pseudouridine synthase, RluA family [Desulfitobacterium hafniense DCB-2] Length: 334. Score: 532. Identity: 31%. E-value: 4E-52. Query: 9 PQEPWLVILYQDDHIMVVNKPSGLLSVPGRLEEHKDSVMTRIQRDYP--------QAESVHRLDMATSGVIVVALTKAAERELKRQFRERVPKKQYVTRVWGHPSPAEGLVDLPLICDWPNRPKQKVCYETGKPAQTEYEVVEYAADNTARVVLKPITGRSHQLRVHMLALGHPILGDRFYASPEARAMAPRLLLHAEMLTITHPAYGNSMTFKAPAV--FLTFPVRLYPHP Sbjct: 102 AENIPLEILYEDEDVLVVNKSQGMVVHPAPGAWTKTLVNALLYHCRNLSGINGVLRPGIVHRIDKDTSGLLVVAKNDLAHQGLAEQIKAHSMARRYLAIVHGVVFEPSGTVEAPIGRDPADRKKMAVVFQNAKEAVTHYEVLERFRD-FTLLEARLETGRTHQIRVHMAYLKHPVLGDPLYGPRKNPFGLQGQMLHAQLLGFQHPRSGEYMEFSAPASGMFQKVLEEIRRDD YP_558676.1 ribosomal large subunit pseudouridine synthase D [Burkholderia xenovorans LB400] Length: 438. Score: 531. Identity: 31%. E-value: 6E-52. Query: 8 PPQEPWLVILYQDDHIMVVNKPSGLLSVPGRLEEHKDSVMTRIQRD------YPQAESVHRLDMATSGVIVVALTKAAERELKRQFRERVPKKQYVTRVWGHPSPAEGLVDLPLICDWPNRPKQ-KVCYETGKPAQTEYEVVE---YAADNTARVVLKPITGRSHQLRVHMLALGHPILGDRFYASPE-------ARAMAPRLLLHAEMLTITHPAYGNSMTFKA--PAVFLTFPVRLYPHPKGC Sbjct: 137 TPEPVPLEIIYEDDTLVVINKPAGMVVHPAAGNWSGTLLNGLLYRYGDAAAGLPRAGIVHRLDKETSGLMVVARTLEAQTDLVRQLQARTVKRRYLALVWGNMP-EEGTIDAPIGRDPRERTRMAVVTSAAGKPARTHFRRVDSAIWERQPVTAIHCDLETGRTHQIRVHCAHIGHPLLGDPVYGRARGKRSVTPLPGGFARQALHAWRLGLIHPKTGRTMQWRADVPEDMEALSAALGLGRDDA ZP_01852455.1 ribosomal large subunit pseudouridine synthase [Planctomyces maris DSM 8797] Length: 342. Score: 531. Identity: 31%. E-value: 6E-52. Query: 5 NYNPPQEPWLVILYQDDHIMVVNKPSGLLSVPGRLEEHKDSVMTRIQRDYP--------QAESVHRLDMATSGVIVVALTKAAERELKRQFRERVPKKQYVTRVWGHPSPAEGLVDLPLICDWPNRPKQKVCYETGKP--AQTEYEVVEYAADNTARVVLKPITGRSHQLRVHMLALGHPILGDRFYAS-------------------PEARAMAPRLLLHAEMLTITHPAYGNSMTFKAPAV--FLTFPVRLYPHPKGC Sbjct: 84 NRLPPEDIPIDIVYEDDWIAIINKPSDMIVHPGKGNYAGTLAGALQYHFDQLSDVAGQYRPGIVHRLDRNTSGIMVVAKDNQVHAKLSAQFEKRDVQKEYRAIVWGRMEFDTDYIDTFMCVHPRAREKMIVCDEGGNARNAFTYYEVIER-YQAFTYVRLKPRTGRTHQLRVHMQHIGHSIVADRVYGGHKSLKMKSLGIQAEADAAELESDVLIERQALHAYCLEFFHPQSGKPMKFEAPLPEDMQNTLAALDQYQKEV YP_001035034.1 ribosomal large subunit pseudouridine synthase D, putative [Streptococcus sanguinis SK36] Length: 298. Score: 530. Identity: 28%. E-value: 8E-52. Query: 6 YNPPQEPWLVILYQDDHIMVVNKPSGLLSVPGRLEEHKDSVMTRIQRDYP--------QAESVHRLDMATSGVIVVALTKAAERELKRQFRERVPKKQYVTRVWGHPSPAEGLVDLPLICDWPNRPKQKVCYETGKPAQTEYEVVEYAADNTARVVLKPITGRSHQLRVHMLALGHPILGDRFYASPEARAMAPRLLLHAEMLTITHPAYGNSMTFKAPAV--FLTFPVRLYP Sbjct: 68 EYVAEDIPLEIVYQDEDVAVINKPQGMVVHPSAGHTSGTLVNALMYHIQDLSGINGVLRPGIVHRIDKDTSGLLMIAKNDQAHVALADELKDKKSLRKYWAIVHGNLPNDRGVIEAPIGRSEKDRKKQAVTAK-GKPALTRFQVLER-FGDYSLVELQLETGRTHQIRVHMAYIGHPVAGDEVYGPRKTLKGH-GQFLHARTLGFTHPRTGEVLEFTAEVPAIFQETLEKLRQ YP_001598812.1 ribosomal large subunit pseudouridine synthase D [Neisseria meningitidis 053442] Length: 392. Score: 529. Identity: 33%. E-value: 9E-52. Query: 8 PPQEPWLVILYQDDHIMVVNKPSGLLSVPGRLEEHKDSVMTRIQR-----DYPQAESVHRLDMATSGVIVVALTKAAERELKRQFRERVPKKQYVTRVWGHPSPAEGLVDLPLICDWPNRPKQKVCYETGKPAQTEYEVVEYAADNTARVVLKPITGRSHQLRVHMLALGHPILGDRFYASPEA----------RAMAPRLLLHAEMLTITHPAYGNSMTFKAPAV Sbjct: 117 VPEPMALDIVYEDDTVIVVNKPAGLVVHPAAGNWTGTLLNGLLAHCPELSQVPRAGIVHRLDKETSGLMVVAKTLPAQNSLVQQLQERTVKRIYRAVANGIVPFD-GKIETQIGRDPHNRLKMAVVKFGGKPAVTHVKVLERYL-AHSYIECSLETGRTHQIRVHMREANHPLAADPVYGNPRHPCGDTVKEAVKSLGARQALHAYRLSFTHPKTGETRSFEAPIP YP_387941.1 pseudouridine synthase, RluD [Desulfovibrio desulfuricans subsp. desulfuricans str. G20] Length: 578. Score: 525. Identity: 28%. E-value: 2E-51. Query: 9 PQEPWLVILYQDDHIMVVNKPSGLLSVPGRLEEHKDSVMTRIQRDYP-------QAESVHRLDMATSGVIVVALTKAAERELKRQFRERVPKKQYVTRVWGHPSPAEGLVDLPLICDWPNRPKQKVCYETGKPAQTEYEVV-----EYAADNTARVVLKPITGRSHQLRVHMLALGHPILGDRFYASPEARAMAP----------RLLLHAEMLTITHPAYGNSMTFKAPAV--FLTFPVRLYPHPKGCLLYINPRVRGFFVSAKL Sbjct: 114 PEEGELEVLYRDAHMLVINKPAGLTVHPAPSCPEGTLVHRLLHHFPELEAQEGFRPGIVHRIDKDTSGLLLIALTEKARLALSDAFAGRRIHKEYLALVKGIPEGDSGEIDAPVGRHPTHKTRMAVVR-GGREALSTWRVLLADPHGGGGTGWTLVAVRIHTGRTHQIRVHMQHTGHPLWGDALYGGMPGREELQTTPALAQTATRQMLHAWKISFDHPVTGAPMQFTLPPPADFGTLIRDLGSRCQRVVITGMP---GCGKSAVL YP_001280463.1 RluA family pseudouridine synthase [Psychrobacter sp. PRwf-1] Length: 420. Score: 523. Identity: 29%. E-value: 4E-51. Query: 1 MGMENYNPPQEPWLVILYQDDHIMVVNKPSGLLSVPGRLEEHKDSVMTRIQR-----DYPQAESVHRLDMATSGVIVVALTKAAERELKRQFRERVPKKQYVTRVWGHPSP--AEGLVDLPLICDWPNRPKQKVCYETGKPAQTEYEVVEYAADNTARVVLKPITGRSHQLRVHMLALGHPILGDRFYASPEARAM------------APRLLLHAEMLTITHPAYGNSMTFKAPAV Sbjct: 168 LEQHGSDQPEDIKLDIIYEDDSVIVINKPVGMVVHPGAGNWSGTLVNGLLYHYPNQAHLPRAGLVHRIDKNTSGLLVIGKTKAAQLELQEQLKDKSVYRHYQCVVAGDAPSLARQRTIDAPIGRHRTQRTKMTVTST-GKTAITHIMKITPLSDTYSLLDVRLETGRTHQIRVHLSHIGHPIIGDDIYGNRQQLRAGLTPEQRQAIQSFPRQALHAYKLGFIHPETGESIELTAPLP ZP_01802060.1 hypothetical protein CdifQ_04003029 [Clostridium difficile QCD-32g58] Length: 429. Score: 523. Identity: 28%. E-value: 5E-51. Query: 9 PQEPWLVILYQDDHIMVVNKPSGLLSVPGRLEEHKDSVMTRIQRDYP---------QAESVHRLDMATSGVIVVALTKAAERELKRQFRERVPKKQYVTRVWGHPSPAEGLVDLPLICDWPNRPKQKVCYETGKPAQTEYEVVEYAADNTARVVLKPITGRSHQLRVHMLALGHPILGDRFYASPEARAMAPRLLLHAEMLTITHPAYGNSMTF--KAPAVFLTFPVRLY Sbjct: 202 PQDIPIDIVYEDDDVLIINKPQDMVVHPAPGNYENTLVNGILYHCKDKLSSINGVIRPGIVHRIDKDTSGLLMIAKNNYAHNFLAEQLKEHTITREYEFICYGVVKEDKITVDKPIGRNPKDRLKMAV-VKDGKNAITHFEVVERF-DKFTHMRARLETGRTHQIRVHALSINHPLLGDFVYGPKETKFKLKGQTLHAKKLGFIHPTTKEYIEFNSELPEYFKEAIKKIK C5VRN0 Ribosomal large subunit pseudouridine synthase D - Clostridium botulinum D str. 1873 Length: 302. Score: 522. Identity: 29%. E-value: 6E-51. Query: 3 MENYNPPQEPWLVILYQDDHIMVVNKPSGLLSVPGRLEEHKDSVMTRIQRDYPQ-----AESVHRLDMATSGVIVVALTKAAERELKRQFRERVPKKQYVTRVWGHPSPAEGLVDLPLICDWPNRPKQKVCYETGKPAQTEYEVVEYAADNTARVVLKPITGRSHQLRVHMLALGHPILGDRFYASPEARAMAPRLLLHAEMLTITHPAYGNSMTFKA--PAVFLTFPVRLYP Sbjct: 72 EEQDIIPEKMDLDIIYEDNDIIVVNKPKGIVVHPTKRHLNGTLSNGVLYYFNDKNENSIVRLVNRLDMDTSGLVLIAKNAYSHMALSRDMQKDDFVKKYLAIVHGNFNEDSGVIDKPIYRVGEGTLKRII-DERGQRSITLFKVIE-QYKNASLVELTLETGRTHQIRVHLSSIGHPIYGDSLYG-EEEPQYIDRQALHAYKLQIPHPKDGKILKLESSLPEDMKNLIRKLSE C0BNA6 Pseudouridine synthase - Flavobacteria bacterium MS024-3C Length: 379. Score: 517. Identity: 29%. E-value: 2E-50. Query: 7 NPPQEPWLVILYQDDHIMVVNKPSGLLSVPGRLEEHKDSVMTRIQRDY-------PQAESVHRLDMATSGVIVVALTKAAERELKRQFRERVPKKQYVTRVWGHPSPAEGLVDLPLICDWPNRPKQKVCYET--GKPAQTEYEVVEYAADNTARVVLKPITGRSHQLRVHMLALGHPILGDRFYASPEARAM----------------APRLLLHAEMLTITHPAYGNSMTFKAPAV Sbjct: 125 LTPEDIPLDVVYEDSDLMVVNKPPGMVVHPGHGNYSGTLINALLFHVKDLPLNADERPGLVHRIDKDTSGLLVVAKTAKAMTHLAKQFFDKTSEREYVAIVWGNVEEEQGTVRGHIGRHPKNRLQMAVFPDGDQGKEAVTHYKVMER-LGYVTLVSCVLETGRTHQIRAHMKHIGHTLFNDERYGGEKILKGTTFTKYKQFVDNAFKALPRQALHAKTLGFVHPSSGELMRFNTPIP YP_002005371.1 23S rRNA pseudouridine synthase [Cupriavidus taiwanensis] Length: 418. Score: 516. Identity: 33%. E-value: 3E-50. Query: 9 PQEPWLVILYQDDHIMVVNKPSGLLSVPGRLEEHKDSVMTRIQRD-----YPQAESVHRLDMATSGVIVVALTKAAERELKRQFRERVPKKQYVTRVWGHPSPAEGLVDLPLICDWPNRPKQ-KVCYETGKPAQTEYEVVEYAA---DNTARVVLKPITGRSHQLRVHMLALGHPILGDRFYASPEARAMAP-----------RLLLHAEMLTITHPAYGNSMTFKA--PAVFLTFPVRL Sbjct: 136 PEDVPLDVVYEDDTLLVINKPAGLVVHPAAGNWSGTVLNGLLHRDPGAASLPRAGIVHRLDKETSGLMVVARTLTAQTDLVRQLQARTVKRTYIALVWGR-TYDEGTIDAPIGRDPRERTRMAIVQTASGKPSRTHFRTLATVPLGRGFVSMVMCKLETGRTHQIRVHFESIGHPLVGDPVYFRATQRGQRPAIRVPLPVPYERQALHAYKLGLVHPATGKHMSWTAQPPEDLQALIDAL YP_391639.1 pseudouridine synthase, RluD [Thiomicrospira crunogena XCL-2] Length: 352. Score: 516. Identity: 29%. E-value: 3E-50. Query: 1 MGMENYNPPQEPWLVILYQDDHIMVVNKPSGLLSVPGRLEEHKDSVMTRIQRDY-----PQAESVHRLDMATSGVIVVALTKAAERELKRQFRERVPKKQYVTRVWGHPSPAEGLVDLPLICDWPNRPKQKVCYETGKPAQTEYEVVEYAADNTARVVLKPITGRSHQLRVHMLALGHPILGDRFYASP------------EARAMAPRLLLHAEMLTITHPAYGNSMTFKA--PAVFLTFPVRLYPHPKG Sbjct: 70 IEDEVSYQAQDIPIEVVYEDEDILVLNKPAGLVVHPGAGNPDGTLLNALLFHYETIREVPRAGIVHRLDKETSGLMVVAKNVPAQTHLVEQLQQHDVERVYDAIVVGKMISG-GTISKPIGRHPTDRKRMAVLTVGGKPATSHYRVLERFRE-HTHVRVKLETGRTHQIRVHMAYLGFPLVGDPVYAGRLRIPQQMMPEFADYLRGFKRQALHAGQLSLTHPRTGKTMKWKVSMPDDMLELIDILRDDMED ZP_01877608.1 23S rRNA/tRNA pseudouridine synthase [Lentisphaera araneosa HTCC2155] Length: 323. Score: 512. Identity: 32%. E-value: 9E-50. Query: 4 ENYNPPQEPWLVILYQDDHIMVVNKPSGLLSVPGRLEEHKDSVMTRIQRDYP----------QAESVHRLDMATSGVIVVALTKAAERELKRQFRERVPKKQYVTRVWGHPSPAEGLVDLPLICDWPNRPKQ--KVCYETGKPAQTEYEVVEYAADNTARVVLKPITGRSHQLRVHMLALGHPILGDRFYASPEARAM--APRLLLHAEMLTITHPAYGNSMTFKAPA--VFLTFPVRLY Sbjct: 80 ESTLLPEDIELDIIYEDDDILVVNKPAGMVVHPGAGNYTGTLVNALLGRDLDTFSAMDDGSSRPGIVHRLDKETSGVIIVAKSAKNLDKLSRSFARRDVEKYYVALCRGTIRVGRDTITSHIGRSRSNRQKMENTNDSNRGKEAISHYKVLADNNGA-TLVKLKIDTGRTHQIRVHMSGINHPVVGDKLYGVRRLDEKESPDRHILHAWRTRIIHPGTQEIMTFTAPLHDDFKSVCDKFG YP_604075.1 pseudouridine synthase, RluD [Deinococcus geothermalis DSM 11300] Length: 341. Score: 511. Identity: 30%. E-value: 1E-49. Query: 9 PQEPWLVILYQDDHIMVVNKPSGLLSVPGRLEEHKDSVMTRIQR------------DYPQAESVHRLDMATSGVIVVALTKAAERELKRQFRERVPKKQYVTRVWGHPS-PAEGLVDLPLICDWPNRPKQKVCYETGKPAQTEYEVVEYAADNT----ARVVLKPITGRSHQLRVHMLALGHPILGDRFYASPEARAMAPRLLLHAEMLTITHPAYGNSMTFKAPAVFLTFPVRLYPHPKGCLLYINPRVRG Sbjct: 92 PEAVPLDVLYEDEHLIAVNKPPGMVTHPAPGVTSGTLVNALLGRLTLPEQPGAVGPDGYRPGIVHRLDKDTSGVIVVAKTVEAHARLAAAFKDRSTHKTYLAIAAGMWKAQGPVSVNAPVGRHPTARQRMTVGGVGPREAQTLFTPLATHPDGHGRTLALVRAQPHTGRTHQIRVHLAHLGSPILGDAVYGRASA--VMPRHALHAQFLTLPHPVTGETLHLHAPVP-DDLLRAWVALGGAVPAELEAPSRG YP_379918.1 pseudouridine synthase, RluD [Chlorobium chlorochromatii CaD3] Length: 363. Score: 511. Identity: 29%. E-value: 1E-49. Query: 6 YNPPQEPWLVILYQDDHIMVVNKPSGLLSVPGRLEEHKDSVMTRIQRDYP----------QAESVHRLDMATSGVIVVALTKAAERELKRQFRERVPKKQYVTRVWGHPSPAEGLVDLPLICDWPNRPKQKVCYETGKPAQTEYE--VVEYAADNTARVVLKPITGRSHQLRVHMLALGHPILGDRFYASPEAR---------------AMAPRLLLHAEMLTITHPAYGNSMTFKAPAVFLTFPVRLYPHPKGCLL Sbjct: 105 ELAPEAIPIAIMYEDDDLMVINKEPGMVVHPAFGNWTGTLANAILHHLGNSAEALDASEMRPGIVHRLDKDTSGLIIIAKNPIALHKLARQFAERKVGKIYKALTWGVPKQASGTITTNIGRSHKNRKVMANFPFEGLEGKTAITDYCVEENLEWFSVMSLRLHTGRTHQIRVHLQHLGLPIVGDVTYGGATPRALPFSKSEHFVKNLLELLPRQALHAETLTFHHPTTGEEITLSAPLP-EDMLQALEKIRGICKL B8K915 Pseudouridine synthase - Vibrio parahaemolyticus 16 Length: 254. Score: 508. Identity: 56%. E-value: 2E-49. Query: 1 MGMENYNPPQEPWLVILYQDDHIMVVNKPSGLLSVPGRLEEHKDSVMTRIQRDYPQAESVHRLDMATSGVIVVALTKAAERELKRQFRERVPKKQYVTRVWGHPSPAEGLVDLPLICDWPNRPKQKVCYETGKPAQTEYEVVEYAADNTARVVLKPITGRSHQLRVHMLALGHPILGDRFYASPEARAMAPRLLLHAEMLTITHPAYGNSMTFKAPAVF Sbjct: 10 MAMTEYNPPREPWVDIVFEDEHILVANKPSGLLSVPGRLEEHYDSLWSRLVAIYPDIQVVHRLDMDTSGLMLLAKHKEAERSLKKQFQYRLTHKVYYARVWGHPTNDNGEIDLPLICDWPNRPRQIVCFDDGKPSKTLYQVVKR-EERTSIVRLLPITGRSHQLRVHMQALGHPIVGDEFYSEGEAFEFSDRLELHAAELSFYHPHSEALQCAFVPCDF YP_002297936.1 ribosomal large subunit pseudouridine synthase D, putative [Rhodospirillum centenum SW] Length: 364. Score: 508. Identity: 29%. E-value: 2E-49. Query: 9 PQEPWLVILYQDDHIMVVNKPSGLLSVPGRLEEHKDSVMTRIQRDYPQ---------AESVHRLDMATSGVIVVALTKAAERELKRQFRERVPKKQYVTRVWGHPSPAEGLVDLPLICDWPNRPKQKVCYETGKPAQTEYEVVEYAADNTARVVLKPITGRSHQLRVHMLALGHPILGDRFYASPEARA-------------MAPRLLLHAEMLTITHPAYGNSMTFKA--PAVFLTFPVRLYPH Sbjct: 120 PQAIPLAIVHEDEDLLVIDKAAEMVVHPAAGNPDGTLVNALLAHCGDRLSGIGGVRRPGIVHRLDKGTSGLLVAAKTDRAHQGLTAQFADRSLSRTYLAVVWGVPAAREGVIEGNIGRHPGDRKRMAVLSRGGKPAVTRYRVVRSFGLLASLVECKLLTGRTHQIRVHMAHVGHPLVGDPLYGRLRPPRKGTAPEPVLRALAGFPRQALHAAALEFRHPASDLKLGFTAALPEDLAGLIQGLETL YP_422549.1 pseudouridylate synthase, 23S RNA-specific [Magnetospirillum magneticum AMB-1] Length: 505. Score: 507. Identity: 28%. E-value: 3E-49. Query: 2 GMENYNPPQEPWLVILYQDDHIMVVNKPSGLLSVPGRLEEHKDSVMTRIQRDYP---------QAESVHRLDMATSGVIVVALTKAAERELKRQFRERVPKKQYVTRVWGHPSPAEGLVDLPLICDWPNRPKQKVCYETGKPAQTEYEVVEYA-ADNTARVVLKPITGRSHQLRVHMLALGHPILGDRFYASPEARAM-------------APRLLLHAEMLTITHPAYGNSMTFKA--PAVFLTFPVRLYPH Sbjct: 253 DAPAQPEPQDIALTVVYEDEDLIVIDKPAGMVVHPAPGNPDETLVNALLAHCGESLAGIGGVKRPGIVHRIDKDTSGLLVAAKTDAAHRGLATQFAAHTLERAYWALVWGTPSPRQGEIEGNIGRNPNDRKKMAVVKSGGKPALTRYRVLKSFAGGAVSLVECRLATGRTHQIRVHMTTQGHPLVGDPVYGRIRGHKGVVLPPEVKTALIQFPRQALHAYLLGFSHPTKGYDVRFESGMPLDINALMQILEVL ZP_01311850.1 Pseudouridine synthase, RluD [Desulfuromonas acetoxidans DSM 684] Length: 350. Score: 505. Identity: 25%. E-value: 5E-49. Query: 9 PQEPWLVILYQDDHIMVVNKPSGLLSVPGRLEEHKDSVMTRIQRDYP--------QAESVHRLDMATSGVIVVALTKAAERELKRQFRERVPKKQYVTRVWGHPSPAEGLVDLPLICDWPNRPKQKVCYETGKPAQTEYEVVEYAA-DNTARVVLKPITGRSHQLRVHMLALGHPILGDRFYASPEARAM------------APRLLLHAEMLTITHPAYGNSMTFKAPAV Sbjct: 76 PEDLPLTVLYEDSDLIVINKAAGMVVHPAAGHSSGTLVNALLYHCHDLSGVGGELRPGIVHRLDKDTSGVMVATKNDVTHNHLAAQFKDHSIQRRYVALVHGQVQNARGTIDAPIGRHPTHRKKMTSKGRGGRRAVTHWKVLRRYDADRLSLLEMRLETGRTHQIRVHLSEMNLPLVGDPLYGNRTRANGINDLEVRNRVHALHRQALHARLLGFIHPRTGDYLEFTSDLP YP_001087541.1 putative pseudouridylate synthase [Clostridium difficile 630] Length: 300. Score: 504. Identity: 30%. E-value: 7E-49. Query: 2 GMENYNPPQEPWLVILYQDDHIMVVNKPSGLLSVPGRLEEHKDSVMTRI-----QRDYPQAESVHRLDMATSGVIVVALTKAAERELKRQFRERVPKKQYVTRVWGHPSPAEGLVDLPLICDWPNRPKQKVCYETGKPAQTEYEVVEYAADNTARVVLKPITGRSHQLRVHMLALGHPILGDRFYASPEARAMAPRLLLHAEMLTITHPAYGNSMTFKA--PAVFLTFPVRLY Sbjct: 71 EEKANFEPQDLNLQIIYDDFDIIMVNKPPFMVVHPTKSHYDKTIANGISYYIDNQKENVKIRFVNRLDMNTSGLVIVAKNAYAHHTLSTAMSENKVEKKYITVVDGIIKENEGTIDEPIYRPTEDSIKRII-DERGQSSVTHYKVIER-LENATVLEVSLETGRTHQIRVHMAHIGHGIIGDELYGYVDEE-LINRQALHAYKLEFEQPRTKEKLKFKADIPEDMKELISKLR B9AQ21 Pseudouridine synthase - Prevotella copri DSM 18205 Length: 387. Score: 502. Identity: 29%. E-value: 1E-48. Query: 1 MGMENYNP---PQEPWLVILYQDDHIMVVNKPSGLLSVPGRLEEHKDSVMTRIQRDY---------PQAESVHRLDMATSGVIVVALTKAAERELKRQFRERVPKKQYVTRVWGHPSPAEGLVDLPLICDWPNRPKQKVCYET---GKPAQTEYEVVEYAADNTARVVLKPITGRSHQLRVHMLALGHPILGDRFYASPEARA----------------MAPRLLLHAEMLTITHPAYGNSMTFKA--PAVFLTFPVR Sbjct: 115 LDRPRHETSIKPEEIAINVVYEDDQLMVVNKEAGMVVHPGAGNFHGTLIQAVAWHLRDMPEFDANDPEVGLVHRIDKDTSGLLVVAKTPTAKNALGKQFFNKTTHRSYNALVWGNIVEDEGRIEGNIGRDPKNRLRMKVFDPDSGIGKTAVTHYKVLER-FGYTTLVQCVLETGRTHQIRAHMKHIGHPLFMDETYGGTEILRGQRSSSYKAFIQNCFKLCPRQALHAKTLGFVHPTTKQQMDFDSEWPNDFRQLIEK C4WHT4 Pseudouridine synthase, RluA family - Ochrobactrum intermedium LMG 3301 Length: 402. Score: 500. Identity: 30%. E-value: 2E-48. Query: 1 MGMENYNPPQEP----WLVILYQDDHIMVVNKPSGLLSVPGRLEEHKDSVMTRIQRDYP---------QAESVHRLDMATSGVIVVALTKAAERELKRQFRERV----PKKQYVTRVWGHPSPAEGLVDLPLICDWPNRPKQKVCYE---TGKPAQTEYEVVEYAADNT------ARVVLKPITGRSHQLRVHMLALGHPILGDRFYAS-------------PEARAMAPRLLLHAEMLTITHPAYGNSMTFKAPAV--FLTFPVRLYPHP Sbjct: 131 VVLPEPEPAEPIAENIPLDILYEDDDLIVINKPAGLVVHPGNGNWTGTLVNALIYHCGDSLSGIGGIRRPGIVHRLDKDTSGVMVVAKNDLSHRHLSEQFADHGRTGDLERAYLALVWGMTERPQGYIDAHLGRSHRDRTKQAVVNEERDDARHAITHYATVEKFGPREDATALASLVECRLETGRTHQIRVHMAHIGHPLVGDMDYGSAYKTKANKLPEPLKEAVRGFHRQALHAFLLAFTHPSSGELMRFEAPVPEDMKHLLENFRKHS ZP_04791326.1 pseudouridine synthase, RluA family [Desulfovibrio vulgaris RCH1] Length: 541. Score: 500. Identity: 29%. E-value: 2E-48. Query: 9 PQEPWLVILYQDDHIMVVNKPSGLLSVPGRLEEHKDSVMTRIQR-------DYPQAESVHRLDMATSGVIVVALTKAAERELKRQFRERVPKKQYVTRVWGHPSPAEGLVDLPLICDWPNRPKQKVCYETGKPAQTEYEVVEY-AADNTARVVLKPITGRSHQLRVHMLALGHPILGDRFYASPEARAMAP-----RLLLHAEMLTITHPAYGNSMTFKAPAV--FLTFPVRLYPHPKGCLLYINPRVRGFFVSAKL Sbjct: 88 PEEGDLTIIHRDEHLLVIDKPAGLTVHPCPSCPEGTLVHRLVHHFDALRAQEGFRPGIVHRIDKDTSGLLLVALSEGVRLKLSEAFAERTVEKEYLALVHGVPP-ATGEVDAPIGRHPTHKVRMAV-VKGGKPARSEWRVLHAAPEGHYALVAVRIHSGRTHQIRVHMAHAGFPLWGDQLYGPGTPARLREQGYGARQMLHAWHLAFTHPVTGERLRFTCPPPQDFPDLAIALARRMTRVVITGSP---GCGKSALL YP_247357.1 ribosomal large subunit pseudouridine synthase D [Rickettsia felis URRWXCal2] Length: 385. Score: 499. Identity: 27%. E-value: 2E-48. Query: 3 MENYNPPQEPWLVILYQDDHIMVVNKPSGLLSVPGRLEEHKDSVMTRIQRDY--------PQAESVHRLDMATSGVIVVALTKAAERELKRQFRERVPKKQYVTRVWGHPSPAEGLVDLPLICDWPNRPKQKVCYETGKPAQTEYEVVE-YAADNTARVVLKPITGRSHQLRVHMLALGHPILGDRFYASPEAR------------AMAPRLLLHAEMLTITHPAYGNSMTFKAPAV Sbjct: 110 EELKIAAANIALDIIYEDDDLIVINKAAGMTVHPGAGHHDDTLVNALLYHTKNLSDIGSAERPGIVHRLDKDTTGLMVVAKNNKAHMLLANQIEQRQVIRKYKALVWGVINPLEGVIKNNIGRSRVDRQKMTILKYGGKEAVTHYKTLELFHKGTISMVECKLSTGRTHQIRVQLSHLKHSVVGDQTYGNNDRKIAHSLPELKAKLIDFKRQALHSWYLSFTHPTSNEIMKFSCELP YP_001741511.1 Pseudouridylate synthase, 23S RNA-specific [Candidatus Cloacamonas acidaminovorans] Length: 351. Score: 500. Identity: 26%. E-value: 2E-48. Query: 1 MGMENYNP----PQEPWLVILYQDDHIMVVNKPSGLLSVPGRLEEHKDSVMTRIQ---------RDYPQAESVHRLDMATSGVIVVALTKAAERELKRQFRERVPKKQYVTRVWGHPSPAEGLVDLPLICDWPNRPKQKVCYETGKPAQTEYEVVEYAADNTARVVLKPITGRSHQLRVHMLALGHPILGDRFYASPE-----------------ARAMAPRLLLHAEMLTITHPAYGNSMTFKAPAV Sbjct: 72 INLPEPEPMNVLPQDIPLDVVYEDEYLAIINKKAGMIVHPGFGNPEGTLVNAILYRFGENLSSGKEFNRPGIVHRLDRGTSGLIIIAKNDLTHAKLSDMFARREIKKTYFAITTGIPEPEKGEIETYLAR-SNKNPRTICVTNEGRYALTHYKTIKTWH-YFALVEINPATGRMHQIRVHFAHIRYPILGDLLYNSRRYVQSLVPQNMKKKVTELLVNHLRRQALHSWKLEFFHPITGYPISVSAPIP C5AFL0 Pseudouridine synthase RluD - Burkholderia glumae BGR1 Length: 400. Score: 497. Identity: 33%. E-value: 4E-48. Query: 8 PPQEPWLVILYQDDHIMVVNKPSGLLSVPGRLEEHKDSVMTRIQRD------YPQAESVHRLDMATSGVIVVALTKAAERELKRQFRERVPKKQYVTRVWGHPSPAEGLVDLPLICDWPNRPKQ-KVCYETGKPAQTEYEVVE---YAADNTARVVLKPITGRSHQLRVHMLALGHPILGDRFYASPE-------ARAMAPRLLLHAEMLTITHPAYGNSMTFKAPAV Sbjct: 128 TPEPVPLAIVYEDEALVVIDKPAGLVVHPAAGNWNGTLLNGLLHRYGEAAAGLPRAGIVHRLDKETSGLMVVARTLAAQTDLVRQLQARTVKRRYFALVWGRTP-ASGTIDAPIGRDPRERTRMAVVTGASGKPARTHFRTVDSVLWQNQPVSAIQCDLETGRTHQIRVHCAHLGHPLLGDPVYGRARGKRSVAALPDGFARQALHAWRLGLVHPVTGRSMQWRCAVP C0QV86 Pseudouridine synthase - Brachyspira hyodysenteriae (strain ATCC 49526 / WA1) Length: 329. Score: 494. Identity: 27%. E-value: 9E-48. Query: 8 PPQEPWLVILYQDDHIMVVNKPSGLLSVPGRLEEHKDSVMTRIQR--------DYPQAESVHRLDMATSGVIVVALTKAAERELKRQFRERVPKKQYVTRVWGHPSPAEGLVDLPLICDWPNRPKQKVCYETGKPAQTEYEVVEYAADNTARVVLKPITGRSHQLRVHMLALGHPILGDRFYASPEARAMAPRLLLHAEMLTITHPAYGNSMTFKA--PAVFLTFP Sbjct: 103 IPENIDLDILYEDKYLLVINKPAGMSVHCSPSEMSGTLVNALLYKIKDFDFVGNKERAGIIHRLDKDTSGLMIIGKNANIVSSIQEQFKNRTIKKIYHAIVVGVLKDNYIEINLPIGRHHVYRKKMTV-REDGKEALTHIKVLKR-FNSHTLIEINLKTGRTHQIRVHSSYKGFPVAGDKIYSKSFSK--YSGLMLVAKKIEFMHPITKELLDFEIDYPDYFTNFL C1SCP2 Pseudouridine synthase - Cryptobacterium curtum DSM 15641 Length: 347. Score: 494. Identity: 22%. E-value: 1E-47. Query: 10 QEPWLVILYQDDHIMVVNKPSGLLSVPGRLEEHKDSVMTRIQRDY----------PQAESVHRLDMATSGVIVVALTKAAERELKRQFRERVPKKQYVTRVWGHPSPAEGLVDLPLICDWPNRPKQKV-CYETGKPAQTEYEVVEYA-----ADNTARVVLKPITGRSHQLRVHMLALGHPILGDRFY--ASPEARAMAPRLLLHAEMLTITHPAYGNSMTFKAPAVFLTFPVRLYPHPKGCLLYINPRVRGFFVSAKLLSVVACGYAFHS Sbjct: 78 EPIPLDVRFEDRWMMAISKQAGLCVHPAPGHEGGTLVNALIYAYGRDSLAHVQGDDRPGIVHRLDMDTSGLMMCAKDDTCGMALQDLVRDHKVDRRYLTLVHGNIAFDTGQIDEPIGRVGDDRLRMKISYRPTARNALTTFTVLERFEAGRADNGYTLLECRLYTGRTHQIRVHMEFIGHCCVGDPLYRWGNEQVNLELSRQFLHSYSLSFNHPMTGDDIALVDGLP-PDLFGALRSLEDRSMGRTEAGKRIFATLATAPRQSEELQAHYF ZP_05069084.1 pseudouridylate synthase [Candidatus Pelagibacter sp. HTCC7211] Length: 325. Score: 491. Identity: 26%. E-value: 2E-47. Query: 3 MENYNPPQEPWLVILYQDDHIMVVNKPSGLLSVPGRLEEHKDSVMTRIQRDYP---------QAESVHRLDMATSGVIVVALTKAAERELKRQFRERVPKKQYVTRVWGHPSPAEGLVDLPLICDWPNRPKQKVCYETGKPAQTEYEVVEYAADNTA----RVVLKPITGRSHQLRVHMLALGHPILGDRF------------YASPEARAMAPRLLLHAEMLTITHPAYGNSMTFKAPAV--FLTFPVRLYPHP Sbjct: 71 EEASLKPYKFKLDIIYEDEDLLVINKPAGIIMHPGAGNYDKTIVNALMNYDKDSLSNIGDELRPGIVHRIDKNTSGLVVVAKNNETHESLSKQFSDHSITRVYQLLIWGKLRPSSGKIDTFITRSSKNRQLMEVSRSKGKRAITNYKTIKIFESNKTPTLSLIECKLETGRTHQIRVHMTYMGNSIVGDDKYKKKYKKLKNVDVGLENLISKLKRQFLHAKTLGFVHPKTDKEMIFSSNLPKELNNLLKMLKNTD YP_595188.1 pseudouridylate synthases, 23S RNA-specific [Lawsonia intracellularis PHE/MN1-00] Length: 541. Score: 491. Identity: 32%. E-value: 3E-47. Query: 9 PQEPWLVILYQDDHIMVVNKPSGLLSVPGRLEEHKDSVMTRIQRDYP-------QAESVHRLDMATSGVIVVALTKAAERELKRQFRERVPKKQYVTRVWGHPSPAEGLVDLPLICDWPNRPKQKVCYETGKPAQTEYEVVEYAADN-TARVVLKPITGRSHQLRVHMLALGHPILGDRFYASPEARAMA--PRLLLHAEMLTITHPAYGNSMTFKAPAV--FLTFPVRLYPHPKGCLLY Sbjct: 78 PEEGFLEILFSDEHLAIINKPPGLTVHPAPSCQESTLVHRLLKYFPKLIEQGGLRPGIVHRIDKDTSGLLCIALTEDTRLKLSKIFLDRKINKEYLALVHGVPSM-EGYIAVPLGRDPKTKVKVAVN-PKGKPAHTEWRVLHRGKNDVYSILALTIQTGRTHQIRVHMKHIGHPLVGDKLYAGGHVNKTFQCNRQMLHAWKLSFEHPITGKKMNFLCPPPKDFLDTVSLLEQEPIRIVIT YP_003048314.1 pseudouridine synthase, RluA family [Methylotenera mobilis JLW8] Length: 368. Score: 489. Identity: 32%. E-value: 4E-47. Query: 3 MENYNPPQEPWLVILYQDDHIMVVNKPSGLLSVPGRLEEHKDSVMTRIQR-----DYPQAESVHRLDMATSGVIVVALTKAAERELKRQFRERVPKKQYVTRVWGHPSPAEGLVDLPLICDWPNRPKQKVCYETGKPAQTEYEVVEYAADNTARVVLKPITGRSHQLRVHMLALGHPILGDRFYAS-------------PEARAMAPRLLLHAEMLTITHPAYGNSMTFKAPA--VFLTFPVRLYP Sbjct: 79 ESRAFIAQDIPLDIVYEDDHILVVNKPAGMVVHPAAGNWDGTLLNALLFHAPQLHDVPRAGIVHRLDKETSGLLVVAKTLNAQTHLVRQLQARTVKREYRAIVWGQL-WRNGVVDQPLGRDPRSRTKMAINRM-GKPAITRYEILERFSV-QTYLRCNLETGRTHQIRVHMQHLKAPLVGDPVYGFRGIVPIRAMTQTLRDAVSQFHRQALHAIKLGLVHPATNEFMEWQIELADDMKVLLEAMRH YP_616788.1 pseudouridine synthase, RluD [Sphingopyxis alaskensis RB2256] Length: 376. Score: 488. Identity: 30%. E-value: 5E-47. Query: 3 MENYNPPQEPWLVILYQDDHIMVVNKPSGLLSVPGRLEEHKDSVMTRIQRDYP---------QAESVHRLDMATSGVIVVALTKAAERELKRQFRERVPKKQYVTRVWGHPSPAEGLVDLPLICDWPNRPKQKVCYET-GKPAQTEYEVVEYAADNTARVVLKPITGRSHQLRVHMLALGHPILGDRFYASPEAR-------AMAPRLLLHAEMLTITHPAYGNSMTF--KAPAVFLTFPVRLY Sbjct: 133 LPAHNAAQDLDLVIAYEDAHLIVIDKPAGMVVHPAAGNLDGTMVNALLHHCAGQLSGIGGVARPGIVHRIDKDTSGLIVAAKHDKAHEGLAKQFAAHSIDRRYLAIATGRPMPANGTVDAALGRSATNRKKMAVVAAGRGKHALTHYRTVEPLQGA-TLIECRLETGRTHQVRVHMAHIGHPLVGDPVYGRARKPLSDVLKARNFARQALHAAHLGFIHPVTGNRIALDSELPADMRELIDELR YP_001413435.1 RluA family pseudouridine synthase [Parvibaculum lavamentivorans DS-1] Length: 482. Score: 488. Identity: 31%. E-value: 6E-47. Query: 10 QEPWLVILYQDDHIMVVNKPSGLLSVPGRLEEHKDSVMTRIQRDYP---------QAESVHRLDMATSGVIVVALTKAAERELKRQF----RERVPKKQYVTRVWGHPSPAEGLVDLPLICDWPNRPKQKVCYE-----TGKPAQTEYEV-VEYAADNTARVVLKPITGRSHQLRVHMLALGHPILGDRFYA-------------SPEARAMAPRLLLHAEMLTITHPAYGNSMTFKAPAV--FLTFPVRLYPHPKG Sbjct: 222 QAIPLEIVYEDADLIVVMKPAGLVVHPAPGNPDMTLVNALVAHCGETLSGIGGEKRPGIVHRLDKETSGLMVVAKTDRAHQGLSAQFAAHGRDGKLTRAYTALTWGVPQTRKGTVDANIARSSHNRSKMATVRDRGEETGGRIAITHYTVKTDYADGLVAEVECRLETGRTHQIRVHMTALGHPLLGDATYGTGMKSRKSKLSPEAQAALERLNRQALHAHHLGFEHPVAGEKMSFDAPLPEDMQELVRALEGVRDG YP_264541.1 ribosomal large subunit pseudouridine synthase D [Psychrobacter arcticus 273-4] Length: 400. Score: 487. Identity: 25%. E-value: 7E-47. Query: 1 MGMENYNPPQEPWLVILYQDDHIMVVNKPSGLLSVPGRLEEHKDSVMTRI-----QRDYPQAESVHRLDMATSGVIVVALTKAAERELKRQFRERVPKKQYVTRVWGHPSP--AEGLVDLPLICDWPNRPKQKVCYETGKPAQTEYEVVEYAADNTARVVLKPITGRSHQLRVHMLALGHPILGDRFYASPEARA------------MAPRLLLHAEMLTITHPAYGNSMTFKAPAV--FLTFPVRL Sbjct: 148 LEQHSADQPEDIAIDVVYEDDEVLVINKPVGMVVHPGAGNQAGTLVNALLYHYPQHHHLPRAGLVHRIDKDTSGLLLIGKTKPAQLALMEQLKDKSVYRHYQCVVAGDAASLLRHRRIDAPIGRHRNQRTKMTVMTA-GREAVTHLLNVTALNGNYCLLDVGLETGRTHQIRVHLSHITYPIVGDRVYGGRRQLRAGLTEAQRQAINNFPRQALHAYILGFVHPTTGEDIEVTTPMPEDMQQLMAVL YP_277698.1 pseudouridine synthase [Candidatus Blochmannia pennsylvanicus str. BPEN] Length: 343. Score: 486. Identity: 27%. E-value: 8E-47. Query: 5 NYNPPQEPWLVILYQDDHIMVVNKPSGLLSVPGRLEEHKDSVMTRIQRDYP-----QAESVHRLDMATSGVIVVALTKAAERELKRQFRERVPKKQYVTRVWGHPSPAEGLVDLPLICDWPNRPKQKVCYETGKPAQTEYEVVEYAADNTARVVLKPITGRSHQLRVHMLALGHPILGDRFYAS------------PEARAMAPRLLLHAEMLTITHPAYGNSMTFKAPAVFLTFPVRLYPHPKGC Sbjct: 97 NNIVPQDIPLDIVYEDDDIVVINKAKNMVVHPGAGNHSGTILNALLYKYPAITEVFRSGIVQRLDKDTTGLMVVAKNMIAYHSLLRLFKKRKIIREYEAVVLGNFLHNEGTINQPIRRHAVHRTRMTVNPM-GKSAITHYSIIES-FGMYTRIRVRLETGRTHQIRVHMAYINHPLLGDHKYGKSTYFIKGISDTVNDCLHVLNRQALHAATLQLCHPITRIKMKWDVPLP-KDIIKLINILRKNE YP_001550096.1 putative pseudouridylate synthase specific to ribosomal large subunit [Prochlorococcus marinus str. MIT 9211] Length: 327. Score: 486. Identity: 28%. E-value: 9E-47. Query: 10 QEPWLVILYQDDHIMVVNKPSGLLSVPGRLEEHKDSVMTRIQRDYP--------QAESVHRLDMATSGVIVVALTKAAERELKRQFRERVPKKQYVTRVWGHPSPAEGLVDLPLICDWPNRPKQKVCYETGKPAQTEYEVVEYAADNTARVVLKPITGRSHQLRVHMLALGHPILGDRFYAS-PEARAMAPRLLLHAEMLTITHPAYGNSMTFKAPAV--FLTFPVRLYPH Sbjct: 89 EKISLDILYEDKYLIVINKQAGIAVHPAPGNKFGTLVNGLLHHCNDLPGISGKLRPGIVHRLDKDTTGCIVVAKTQEALVNLQKQIQTRVASRIYLAIVHGVPKGDKGTIIGAIGRHPVDRKKYAVVTNEMARYACTHWELKERLGDYSLLSFKLDTGR